Publications by authors named "David J Matson"

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The discovery of benzoxazine sulfonamide inhibitors of Na1.7: Tools that bridge efficacy and target engagement.
Daniel S La, Emily A Peterson, Christiane Bode, Alessandro A Boezio, Howard Bregman, David J Matson

Bioorg Med Chem Lett· August 2017

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Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.
Xin Huang, Paul L Shaffer, Shawn Ayube, Howard Bregman, Hao Chen, David J Matson

Nat Struct Mol Biol· February 2017

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Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund's Adjuvant Models of Pain.
David J Matson, Darryl T Hamamoto, Howard Bregman, Melanie Cooke, Erin F DiMauro

PLoS One· June 2016

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Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain.
Jacinthe Gingras, Sarah Smith, David J Matson, Danielle Johnson, Kim Nye

PLoS One· April 2015

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Discovery and optimization of aminopyrimidinones as potent and state-dependent Nav1.7 antagonists.
Hanh Nho Nguyen, Howie Bregman, John L Buchanan, Bingfan Du, Elma Feric, David J Matson

Bioorg Med Chem Lett· January 2012

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Locomotor activity in a novel environment as a test of inflammatory pain in rats.
David J Matson, Daniel C Broom, Daniel N Cortright

Methods Mol Biol· June 2010

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Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.
Daniel C Broom, David J Matson, Elizabeth Bradshaw, Marianne E Buck, Robin Meade

J Pharmacol Exp Ther· December 2008

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New frontiers in assessing pain and analgesia in laboratory animals.
Daniel N Cortright, David J Matson, Daniel C Broom

Expert Opin Drug Discov· September 2008

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Inflammation-induced reduction of spontaneous activity by adjuvant: A novel model to study the effect of analgesics in rats.
David J Matson, Daniel C Broom, Susan R Carson, James Baldassari, John Kehne

J Pharmacol Exp Ther· January 2007

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