Publications by authors named "David Kelsen"

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Pembrolizumab and Olaparib (POLAR) Maintenance Therapy in Metastatic Pancreatic Cancer With or Without Homologous Repair Deficiency: A Biomarker Selected Phase II Trial.
Wungki Park, Catherine O'Connor, Joanne Chou, Marc Hilmi, Zeynep Tarcan, David Kelsen

Res Sq· September 2025

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Docetaxel as part of first-line chemotherapy for gastric cancer.
David Kelsen

Lancet Oncol· June 2025

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Sarcoid-like reactions in patients treated with checkpoint inhibitors for advanced solid tumors.
Ian Nykaza, Yonina R Murciano-Goroff, Antoine Desilets, Guilherme Harada, Michael A Postow, David Paul Kelsen

Oncologist· May 2025

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Adjuvant modified FOLFIRINOX for resected pancreatic adenocarcinoma: clinical insights and genomic features from a large contemporary cohort.
Fergus Keane, Catherine O'Connor, Drew Moss, Joanne F Chou, Maria A Perry, David Kelsen

J Natl Cancer Inst· March 2025

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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2.
Serena Lucotti, Yusuke Ogitani, Candia M Kenific, Jacob Geri, Young Hun Kim, David Kelsen

Cell· March 2025

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Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival.
Anna M Varghese, Maria A Perry, Joanne F Chou, Subhiksha Nandakumar, Daniel Muldoon, David P Kelsen

Nat Med· February 2025

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Multimodal Treatment in Locally Advanced Esophageal Adenocarcinoma - Two Interventions Better Than Three?
David P Kelsen

N Engl J Med· January 2025

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Assessment of the Feasibility of Hyperpolarized [1-C]pyruvate Whole-Abdomen MRI using DO Solvation in Humans.
Guannan Zhang, Kofi Deh, Hijin Park, Charles H Cunningham, Nadia D Bragagnolo, David Kelsen

J Magn Reson Imaging· December 2024

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Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer.
Catherine A O'Connor, Emily Harrold, David Lin, Henry Walch, Andrea Gazzo, David Kelsen

JAMA Oncol· November 2024

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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Linda Bojmar, Constantinos P Zambirinis, Jonathan M Hernandez, Jayasree Chakraborty, Lee Shaashua, David Kelsen

Nat Med· August 2024

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Optimization of ultracentrifugation-based method to enhance the purity and proteomic profiling depth of plasma-derived extracellular vesicles and particles.
Zurong Wan, Jinghua Gu, Uthra Balaji, Linda Bojmar, Henrik Molina, David P Kelsen

J Extracell Biol· July 2024

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Mapping the tumor stress network reveals dynamic shifts in the stromal oxidative stress response.
Chen Lior, Debra Barki, Coral Halperin, Christine A Iacobuzio-Donahue, David Kelsen

Cell Rep· May 2024

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Pharmaceutical Agents as Potential Drivers in the Development of Early-Onset Colorectal Cancer: Case-Control Study.
Irit Ben-Aharon, Ran Rotem, Cheli Melzer-Cohen, Gilad Twig, Andrea Cercek, David Kelsen

JMIR Public Health Surveill· December 2023

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Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Gang Wang, Jianlong Li, Linda Bojmar, Haiyan Chen, Zhong Li, David Kelsen

Nature· June 2023

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Perioperative versus total neoadjuvant chemotherapy in gastric cancer.
Jessica Yang, Megan Greally, Vivian E Strong, Daniel G Coit, Joanne F Chou, David P Kelsen

J Gastrointest Oncol· June 2023

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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
Walid K Chatila, Henry Walch, Jaclyn F Hechtman, Sydney M Moyer, Valeria Sgambati, David Kelsen

Nat Commun· January 2023

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Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice.
Wungki Park, Catherine A O'Connor, Chaitanya Bandlamudi, Daniella Forman, Joanne F Chou, David P Kelsen

Clin Cancer Res· November 2022

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BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.
Lee Shaashua, Aviad Ben-Shmuel, Meirav Pevsner-Fischer, Gil Friedman, Oshrat Levi-Galibov, David Kelsen

Nat Commun· October 2022

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Attitudes toward preimplantation genetic testing and quality of life among individuals with hereditary diffuse gastric cancer syndrome.
Ibrahim H Shah, Erin E Salo-Mullen, Kimberly A Amoroso, David Kelsen, Zsofia K Stadler

Hered Cancer Clin Pract· September 2022

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Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.
Kenneth H Yu, Jennifer Park, Avni Mittal, Ghassan K Abou-Alfa, Imane El Dika, David P Kelsen

Cancer· August 2022

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PD-L1 expression and overall survival in Asian and western patients with gastric cancer.
Sun Young Rha, Geoffrey Y Ku, Hyo Song Kim, Hyun Cheol Chung, Fatemeh Ghazanfari Amlashi, David P Kelsen

Future Oncol· July 2022

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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.
Ori Hassin, Nishanth Belugali Nataraj, Michal Shreberk-Shaked, Yael Aylon, Rona Yaeger, David Kelsen

Nat Commun· May 2022

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Phase I/Ib study of crenolanib with ramucirumab and paclitaxel as second-line therapy for advanced esophagogastric adenocarcinoma.
Ryan H Moy, Megan Greally, Joanne F Chou, Jia Li, Avni M Desai, David P Kelsen

Cancer Chemother Pharmacol· February 2022

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Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.
Parisa Momtaz, Catherine A O'Connor, Joanne F Chou, Marinela Capanu, Wungki Park, David P Kelsen

Cancer· December 2021

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Prognostic significance of T-cell-inflamed gene expression profile and PD-L1 expression in patients with esophageal cancer.
Torben Steiniche, Sun Young Rha, Hyun Cheol Chung, Jeanette Baehr Georgsen, Morten Ladekarl, David P Kelsen

Cancer Med· December 2021

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