Publications by authors named "David Lambright"

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Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.
Holger Hengel, Shabab B Hannan, Selina Reich, Danique Beijer, Johanna Roller, David Lambright

Brain· August 2025

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Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling.
YouJin Lee, Qing Ouyang, Hasib Aamir Riaz, Li Ma, Morgan Fleishman, David G Lambright

bioRxiv· December 2024

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High-Throughput Assay for Profiling the Substrate Specificity of Rab GTPase-Activating Proteins.
Ashwini K Mishra, David G Lambright

Methods Mol Biol· January 2022

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Systems-level effects of allosteric perturbations to a model molecular switch.
Tina Perica, Christopher J P Mathy, Jiewei Xu, Gwendolyn Μ Jang, Yang Zhang, David G Lambright

Nature· November 2021

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Propelling COPII vesicle biogenesis at the endoplasmic reticulum.
Jianjun Duan, David G Lambright

Structure· August 2021

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Coordination of Grp1 recruitment mechanisms by its phosphorylation.
Jian Li, David G Lambright, Victor W Hsu

Mol Biol Cell· December 2020

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X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.
Michael W Struck, Gregory J Pazour, David G Lambright

Structure· April 2020

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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
Sanchaita Das, Andrew W Malaby, Agata Nawrotek, Wenhua Zhang, Mahel Zeghouf, David G Lambright

Structure· December 2019

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ARF GTPases and their GEFs and GAPs: concepts and challenges.
Elizabeth Sztul, Pei-Wen Chen, James E Casanova, Jacqueline Cherfils, Joel B Dacks, David G Lambright

Mol Biol Cell· May 2019

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TRAPPing a Rab GTPase by the Tail.
Jianjun Duan, David G Lambright

Dev Cell· January 2019

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Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.
Andrew W Malaby, Sanchaita Das, Srinivas Chakravarthy, Thomas C Irving, Osman Bilsel, David G Lambright

Structure· January 2018

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Membrane Trafficking: An Endosome Tether Meets a Rab and Collapses.
Sanchaita Das, David G Lambright

Curr Biol· October 2016

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Special Issue: GTPases in trafficking, autophagy, and disease (FASEB SRC).
Richard A Kahn, David Lambright, Antonella De Matteis

Small GTPases· October 2016

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Invited review: Small GTPases and their GAPs.
Ashwini K Mishra, David G Lambright

Biopolymers· August 2016

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High-throughput assay for profiling the substrate specificity of Rab GTPase-activating proteins.
Ashwini K Mishra, David G Lambright

Methods Mol Biol· March 2016

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A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.
Richard A Kahn, David G Lambright

Structure· November 2015

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Methods for analysis of size-exclusion chromatography-small-angle X-ray scattering and reconstruction of protein scattering.
Andrew W Malaby, Srinivas Chakravarthy, Thomas C Irving, Sagar V Kathuria, Osman Bilsel, David G Lambright

J Appl Crystallogr· August 2015

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Molecular insights into Rab7-mediated endosomal recruitment of core retromer: deciphering the role of Vps26 and Vps35.
Amulya Priya, Inna V Kalaidzidis, Yannis Kalaidzidis, David Lambright, Sunando Datta

Traffic· January 2015

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Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking.
Sylvia Stockler, Silvia Corvera, David Lambright, Kevin Fogarty, Ekaterina Nosova

Orphanet J Rare Dis· September 2014

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The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.
Andree Hubber, Kohei Arasaki, Fubito Nakatsu, Camille Hardiman, David Lambright

PLoS Pathog· July 2014

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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity.
Motiur Rahman, Niraj K Nirala, Alka Singh, Lihua Julie Zhu, Kaori Taguchi, David G Lambright

J Cell Biol· July 2014

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Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.
Claudia M Del Campo, Ashwini K Mishra, Yu-Hsiu Wang, Craig R Roy, Paul A Janmey, David G Lambright

Structure· March 2014

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The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism.
Ashwini K Mishra, Claudia M Del Campo, Robert E Collins, Craig R Roy, David G Lambright

J Biol Chem· August 2013

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Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors.
Andrew W Malaby, Bert van den Berg, David G Lambright

Proc Natl Acad Sci U S A· August 2013

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Germline mutations affecting Gα11 in hypoparathyroidism.
Michael Mannstadt, Mark Harris, Bert Bravenboer, Sridhar Chitturi, Koen M A Dreijerink, David G Lambright

N Engl J Med· June 2013

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