Publications by authors named "David Liberg"

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HPV16-Expressing Tumors Release Multiple IL1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine.
Morgane Lecointre, Jérémy Guillot, Rachel Marcone, Dilara Ozdoganlar, Marjorie Cayatte, David Liberg

Cancer Discov· July 2025

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IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion.
Madelene Lindkvist, Anna Göthlin Eremo, Geena Varghese Paramel, Sheikh Anisul Haque, Camilla Rydberg Millrud, David Liberg

J Am Heart Assoc· May 2025

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IL1RAP Blockade With a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis.
Diego A Lema, Gabriel Jakobsson, Abdel Daoud, David Elias, Monica V Talor, David Liberg

Circ Heart Fail· December 2024

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Blocking IL1RAP on cancer-associated fibroblasts in pancreatic ductal adenocarcinoma suppresses IL-1-induced neutrophil recruitment.
Nils Hansen, Pablo Peña-Martínez, Petter Skoog, Katrin Reinbach, Finja C Hansen, David Liberg

J Immunother Cancer· December 2024

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Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Caitríona Grönberg, Sara Rattik, Cuong Tran-Manh, Xiang Zhou, Aleix Rius Rigau, David Liberg

Ann Rheum Dis· August 2024

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Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.
Megan Mulholland, Marie A C Depuydt, Gabriel Jakobsson, Irena Ljungcrantz, Andrietta Grentzmann, David Liberg

Cardiovasc Res· May 2024

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Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.
James K Fields, Elin Jaensson Gyllenbäck, Marek Bogacz, Juliet Obi, Gabriel Svensson Birkedal, David Liberg

Cell Rep· May 2024

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Blockade of IL-1α and IL-1β signaling by the anti-IL1RAP antibody nadunolimab (CAN04) mediates synergistic anti-tumor efficacy with chemotherapy.
Camilla Rydberg Millrud, Adnan Deronic, Caitríona Grönberg, Elin Jaensson Gyllenbäck, Karin von Wachenfeldt, David Liberg

Cancer Immunol Immunother· March 2023

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First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours.
Debbie Robbrecht, Christiane Jungels, Morten Mau Sorensen, Iben Spanggaard, Ferry Eskens, David Liberg

Br J Cancer· April 2022

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Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor.
James K Fields, Kyle Kihn, Gabriel S Birkedal, Erik H Klontz, Kjell Sjöström, David Liberg

Front Immunol· February 2022

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Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells.
Paramita Chakraborty, Per Bjork, Eva Källberg, Anders Olsson, Matteo Riva, David Liberg

PLoS One· July 2016

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Paquinimod reduces skin fibrosis in tight skin 1 mice, an experimental model of systemic sclerosis.
Martin Stenström, Helén Carlsson Nyhlén, Marie Törngren, David Liberg, Birgitta Sparre

J Dermatol Sci· July 2016

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S100A9 as a Pharmacological Target Molecule in Inflammation and Cancer.
Tomas Leanderson, David Liberg, Fredrik Ivars

Endocr Metab Immune Disord Drug Targets· February 2016

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Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.
Anders Olsson, Jessica Nakhlé, Anette Sundstedt, Pascale Plas, Anne-Laure Bauchet, David Liberg

J Immunother Cancer· December 2015

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Common interactions between S100A4 and S100A9 defined by a novel chemical probe.
Per Björk, Eva Källberg, Ulf Wellmar, Matteo Riva, Anders Olsson, David Liberg

PLoS One· December 2013

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CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden.
Eva Källberg, Martin Stenström, David Liberg, Fredrik Ivars, Tomas Leanderson

BMC Immunol· December 2012

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S100A9 interaction with TLR4 promotes tumor growth.
Eva Källberg, Thomas Vogl, David Liberg, Anders Olsson, Per Björk

PLoS One· August 2012

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Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.
Per Björk, Anders Björk, Thomas Vogl, Martin Stenström, David Liberg

PLoS Biol· April 2009

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Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.
Elizabeth C Thompson, Bradley S Cobb, Pierangela Sabbattini, Sonja Meixlsperger, Vania Parelho, David Liberg

Immunity· March 2007

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CArG box-binding factor-A interacts with multiple motifs in immunoglobulin promoters and has a regulated subcellular distribution.
Alaitz Aranburu, David Liberg, Bent Honoré, Tomas Leanderson

Eur J Immunol· August 2006

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SPI-C and STAT6 can cooperate to stimulate IgE germline transcription.
Robert Carlsson, Kaisa Thorell, David Liberg, Tomas Leanderson

Biochem Biophys Res Commun· June 2006

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Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics.
Peter Akerblad, Robert Månsson, Anna Lagergren, Simonetta Westerlund, Barbro Basta, David Liberg

Physiol Genomics· October 2005

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Upstream of Ikaros.
David Liberg, Stephen T Smale, Matthias Merkenschlager

Trends Immunol· November 2003

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RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development.
Panagiotis Tsapogas, Thomas Breslin, Sven Bilke, Anna Lagergren, Robert Månsson, David Liberg

J Leukoc Biol· July 2003

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Genomic structure of mouse SPI-C and genomic structure and expression pattern of human SPI-C.
Robert Carlsson, Anna Hjalmarsson, David Liberg, Christine Persson, Tomas Leanderson

Gene· October 2002

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