Publications by authors named "David Litchfield"

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Covalent Inhibition of the Peptidyl-Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2-OS Cells.
Scott E Roffey, Owen Hovey, Kristina Jurcic, Kun Ping Lu, Xiao Zhen Zhou, David W Litchfield

Proteomics· July 2025

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Novel Pannexin 1 isoform is increased in cancer.
Brooke L O'Donnell, Dan Stefan, Yu-Hsin Chiu, Michael J Zeitz, Justin Tang, David W Litchfield

bioRxiv· January 2025

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Body weight control via protein kinase CK2: diet-induced obesity counteracted by pharmacological targeting.
Laura M Buchwald, Ditte Neess, Daniel Hansen, Thomas K Doktor, Vignesh Ramesh, David W Litchfield

Metabolism· January 2025

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Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells.
Barbara Guerra, Kristina Jurcic, Rachelle van der Poel, Samantha Lynn Cousineau, Thomas K Doktor, David W Litchfield

Cancer Cell Int· December 2024

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Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Maria Reinecke, Paul Brear, Larsen Vornholz, Benedict-Tilmann Berger, Florian Seefried, David William Litchfield

Nat Chem Biol· May 2024

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Towards the CSNK2 phosphoproteome - With lessons from the COVID-19 pandemic to revealing the secrets of CSNK2 and its promise as a therapeutic target.
David W Litchfield, Laszlo Gyenis, Daniel Menyhart, Scott E Roffey

Biochim Biophys Acta Gen Subj· October 2023

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Involvement of the AKT Pathway in Resistance to Erlotinib and Cabozantinib in Triple-Negative Breast Cancer Cell Lines.
Cory Lefebvre, Sierra Pellizzari, Vasudeva Bhat, Kristina Jurcic, David W Litchfield

Biomedicines· August 2023

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Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics.
Laszlo Gyenis, Daniel Menyhart, Edward S Cruise, Kristina Jurcic, Scott E Roffey, David W Litchfield

Front Mol Biosci· June 2022

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CSNK2 in cancer: pathophysiology and translational applications.
Scott W Strum, Laszlo Gyenis, David W Litchfield

Br J Cancer· April 2022

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Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes.
Rafael E Sanchez-Pupo, Brooke L O'Donnell, Danielle Johnston, Laszlo Gyenis, David W Litchfield

Mol Biol Cell· March 2022

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CK2 Regulation: Perspectives in 2021.
Scott E Roffey, David W Litchfield

Biomedicines· September 2021

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Correction for St-Denis et al., "Evidence for Regulation of Mitotic Progression through Temporal Phosphorylation and Dephosphorylation of CK2α".
Nicole A St-Denis, D Richard Derksen, David W Litchfield

Mol Cell Biol· July 2021

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Development of a potent and selective chemical probe for the pleiotropic kinase CK2.
Carrow I Wells, David H Drewry, Julie E Pickett, Amelie Tjaden, Andreas Krämer, David W Litchfield

Cell Chem Biol· April 2021

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Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein.
Daniel Nouri-Nejad, Brooke L O'Donnell, Chetan S Patil, Rafael E Sanchez-Pupo, Danielle Johnston, David W Litchfield

Mol Biol Cell· March 2021

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In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy.
Bojana Kravic, Angelika B Harbauer, Vanina Romanello, Luca Simeone, F-Nora Vögtle, David Litchfield

Autophagy· February 2019

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N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation.
Laura E Bowie, Tamara Maiuri, Melanie Alpaugh, Michelle Gabriel, Nicolas Arbez, David W Litchfield

Proc Natl Acad Sci U S A· July 2018

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CK2β regulates thrombopoiesis and Ca-triggered platelet activation in arterial thrombosis.
Patrick Münzer, Britta Walker-Allgaier, Sascha Geue, Friederike Langhauser, Eva Geuss, David W Litchfield

Blood· December 2017

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BIRC6 mediates imatinib resistance independently of Mcl-1.
Denis O Okumu, Michael P East, Merlin Levine, Laura E Herring, Raymond Zhang, David W Litchfield

PLoS One· September 2017

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Protein Kinase CK2: Intricate Relationships within Regulatory Cellular Networks.
Teresa Nuñez de Villavicencio-Diaz, Adam J Rabalski, David W Litchfield

Pharmaceuticals (Basel)· March 2017

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Cellular interaction influenced by surface modification strategies of gelatin-based nanoparticles.
Wai Hei Tse, Laszlo Gyenis, David W Litchfield, Jin Zhang

J Biomater Appl· February 2017

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Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder.
Yangyang Bian, Lei Li, Mingming Dong, Xuguang Liu, Tomonori Kaneko, David Litchfield

Nat Chem Biol· November 2016

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Molecular Pathways: Emergence of Protein Kinase CK2 (CSNK2) as a Potential Target to Inhibit Survival and DNA Damage Response and Repair Pathways in Cancer Cells.
Adam J Rabalski, Laszlo Gyenis, David W Litchfield

Clin Cancer Res· June 2016

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mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.
Valentina Gandin, Laia Masvidal, Marie Cargnello, Laszlo Gyenis, Shannon McLaughlan, David Litchfield

Nat Commun· April 2016

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GAR22β regulates cell migration, sperm motility, and axoneme structure.
Ivonne Gamper, David Fleck, Meltem Barlin, Marc Spehr, Sara El Sayad, David W Litchfield

Mol Biol Cell· January 2016

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Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells.
Sarah A Dick, Natasha C Chang, Nicolas A Dumont, Ryan A V Bell, Charis Putinski, David W Litchfield

Proc Natl Acad Sci U S A· September 2015

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