Publications by authors named "David Lleres"

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Redefining enhancer action: Insights from structural, genomic, and single-molecule perspectives.
David Llères, Andres Cardozo Gizzi, Marcelo Nollmann

Curr Opin Cell Biol· August 2025

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Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8.
Yannick Perez, Fatima Alhourani, Julie Patouillard, Cyril Ribeyre, Marion Larroque, David Lleres

Cell Cycle· August 2025

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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions.
Cyril Esnault, Talha Magat, Amal Zine El Aabidine, Encar Garcia-Oliver, Anne Cucchiarini, David Lleres

Nat Genet· August 2023

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Evidence for low nanocompaction of heterochromatin in living embryonic stem cells.
Claire Dupont, Dhanvantri Chahar, Antonio Trullo, Thierry Gostan, Caroline Surcis

EMBO J· June 2023

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Exploring chromatin structural roles of non-coding RNAs at imprinted domains.
David Llères, Yui Imaizumi, Robert Feil

Biochem Soc Trans· August 2021

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The 20S proteasome activator PA28γ controls the compaction of chromatin.
Didier Fesquet, David Llères, Charlotte Grimaud, Cristina Viganò, Francisca Méchali

J Cell Sci· February 2021

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A Role for COMPASS in Germline Chromatin Organization.
Marion Herbette, Valérie Robert, Aymeric Bailly, Loïc Gely, Robert Feil

Cells· September 2020

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CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains.
David Llères, Benoît Moindrot, Rakesh Pathak, Vincent Piras, Mélody Matelot

Genome Biol· December 2019

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Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing.
Muhammad Shoaib, David Walter, Peter J Gillespie, Fanny Izard, Birthe Fahrenkrog, David Lleres

Nat Commun· September 2018

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Meg3 Non-coding RNA Expression Controls Imprinting by Preventing Transcriptional Upregulation in cis.
Ildem Sanli, Sébastien Lalevée, Marco Cammisa, Aurélien Perrin, Florence Rage

Cell Rep· April 2018

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Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations.
Ashwat Visvanathan, Kashif Ahmed, Liron Even-Faitelson, David Lleres, David P Bazett-Jones

PLoS One· October 2017

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KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients.
Luisa Quinti, Sharadha Dayalan Naidu, Ulrike Träger, Xiqun Chen, Kimberly Kegel-Gleason

Proc Natl Acad Sci U S A· June 2017

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Quantitative FLIM-FRET Microscopy to Monitor Nanoscale Chromatin Compaction In Vivo Reveals Structural Roles of Condensin Complexes.
David Llères, Aymeric P Bailly, Aurélien Perrin, David G Norman, Dimitris P Xirodimas

Cell Rep· February 2017

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The cell proliferation antigen Ki-67 organises heterochromatin.
Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas

Elife· March 2016

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Monitoring Keap1-Nrf2 interactions in single live cells.
Liam Baird, Sam Swift, David Llères, Albena T Dinkova-Kostova

Biotechnol Adv· November 2014

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ICR noncoding RNA expression controls imprinting and DNA replication at the Dlk1-Dio3 domain.
Satya K Kota, David Llères, Tristan Bouschet, Ryutaro Hirasawa, Alice Marchand

Dev Cell· October 2014

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Epigenetic deregulation of genomic imprinting in humans: causal mechanisms and clinical implications.
Michael Girardot, Robert Feil, David Llères

Epigenomics· December 2013

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Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex.
Liam Baird, David Llères, Sam Swift, Albena T Dinkova-Kostova

Proc Natl Acad Sci U S A· September 2013

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Perturbation of chromatin structure globally affects localization and recruitment of splicing factors.
Ignacio E Schor, David Llères, Guillermo J Risso, Andrea Pawellek, Jernej Ule

PLoS One· May 2013

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Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.
David Llères, Marco Denegri, Marco Biggiogera, Paul Ajuh, Angus I Lamond

EMBO Rep· June 2010

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Quantitative analysis of chromatin compaction in living cells using FLIM-FRET.
David Llères, John James, Sam Swift, David G Norman, Angus I Lamond

J Cell Biol· November 2009

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Spatial mapping of splicing factor complexes involved in exon and intron definition.
Jonathan D Ellis, David Llères, Marco Denegri, Angus I Lamond, Javier F Cáceres

J Cell Biol· June 2008

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Detecting protein-protein interactions in vivo with FRET using multiphoton fluorescence lifetime imaging microscopy (FLIM).
David Llères, Samuel Swift, Angus I Lamond

Curr Protoc Cytom· October 2007

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Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells.
Anthony Kar Lun Leung, Daniel Gerlich, Gail Miller, Carol Lyon, Yun Wah Lam, David Lleres

J Cell Biol· September 2004

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Dependence of the cellular internalization and transfection efficiency on the structure and physicochemical properties of cationic detergent/DNA/liposomes.
David Llères, Jean-Marc Weibel, Denis Heissler, Guy Zuber, Guy Duportail

J Gene Med· April 2004

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