Publications by authors named "David Lockhart"

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Lipid nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models.
Amanda J Smith, Patrick R Sears, Mirko Hennig, Rumpa B Bhattacharjee, Weining Yin, David J Lockhart

J Cell Sci· October 2025

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Quicker team launch times for urgent priority neonatal retrievals: A Quality Improvement Initiative study.
Saumil Desai, Kevin George, Kylie McDonald, Alysha Timoney, Dahna Kelland, David Lockhart

J Perinatol· July 2025

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Dual SORT LNPs for multi-organ base editing.
Minjeong Kim, Eunice S Song, Joseph C Chen, Sumanta Chatterjee, Yehui Sun, David J Lockhart

Nat Biotechnol· June 2025

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Inhaled mRNA therapy for treatment of primary ciliary dyskinesia.
Mirko Hennig, Rumpa B Bhattacharjee, Ishita Agarwal, Ali Alfaifi, Jade E Casillas, David J Lockhart

Proc Natl Acad Sci U S A· May 2025

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In vivo editing of lung stem cells for durable gene correction in mice.
Yehui Sun, Sumanta Chatterjee, Xizhen Lian, Zachary Traylor, Sandhya R Sattiraju, David J Lockhart

Science· June 2024

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Duvoglustat HCl Increases Systemic and Tissue Exposure of Active Acid α-Glucosidase in Pompe Patients Co-administered with Alglucosidase α.
Priya Kishnani, Mark Tarnopolsky, Mark Roberts, Kumarswamy Sivakumar, Majed Dasouki, David J Lockhart

Mol Ther· May 2017

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The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat.
Elfrida R Benjamin, Maria Cecilia Della Valle, Xiaoyang Wu, Evan Katz, Farhana Pruthi, David J Lockhart

Genet Med· April 2017

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Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study.
Derralynn A Hughes, Kathleen Nicholls, Suma P Shankar, Gere Sunder-Plassmann, David Koeller, David J Lockhart

J Med Genet· April 2017

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Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.
Dominique P Germain, Derralynn A Hughes, Kathleen Nicholls, Daniel G Bichet, Roberto Giugliani, David J Lockhart

N Engl J Med· August 2016

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Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase.
David G Warnock, Daniel G Bichet, Myrl Holida, Ozlem Goker-Alpan, Kathy Nicholls, David J Lockhart

PLoS One· May 2016

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The Impact of Obesity on the 30-day Morbidity and Mortality After Surgery for Ovarian Cancer.
Haider Mahdi, Ahmed A Alhassani, David Lockhart, Hussain Al-Fatlawi, Andrew Wiechert

Int J Gynecol Cancer· February 2016

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Impact of Age on 30-Day Mortality and Morbidity in Patients Undergoing Surgery for Ovarian Cancer.
Haider Mahdi, Andrew Wiechert, David Lockhart, Peter G Rose

Int J Gynecol Cancer· September 2015

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Coformulation of a Novel Human α-Galactosidase A With the Pharmacological Chaperone AT1001 Leads to Improved Substrate Reduction in Fabry Mice.
Su Xu, Yi Lun, Nastry Brignol, Rick Hamler, Adriane Schilling, David J Lockhart

Mol Ther· July 2015

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Predictors of surgical site infection in women undergoing hysterectomy for benign gynecologic disease: a multicenter analysis using the national surgical quality improvement program data.
Haider Mahdi, Sarah Goodrich, David Lockhart, Robert DeBernardo, Mehdi Moslemi-Kebria

J Minim Invasive Gynecol· June 2015

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Impact of age on 30-day mortality and morbidity in patients undergoing surgery for endometrial cancer.
Haider Mahdi, David Lockhart, Kathryn A Maurer

Gynecol Oncol· April 2015

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Prognostic impact of lymphadenectomy in uterine clear cell carcinoma.
Haider Mahdi, David Lockhart, Mehdi Moselmi-Kebria

J Gynecol Oncol· April 2015

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The pharmacological chaperone AT2220 increases the specific activity and lysosomal delivery of mutant acid alpha-glucosidase, and promotes glycogen reduction in a transgenic mouse model of Pompe disease.
Richie Khanna, Allan C Powe, Yi Lun, Rebecca Soska, Jessie Feng, David J Lockhart

PLoS One· March 2015

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The impact of obesity on the 30-day morbidity and mortality after surgery for endometrial cancer.
Haider Mahdi, Amelia M Jernigan, Qataralnada Aljebori, David Lockhart, Mehdi Moslemi-Kebria

J Minim Invasive Gynecol· January 2015

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Racial disparity in 30-day morbidity and mortality after surgery for ovarian cancer.
Haider Mahdi, Amelia Jernigan, David Lockhart, Mehdi Moslemi-Kebria, Peter G Rose

Int J Gynecol Cancer· January 2015

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A GCase chaperone improves motor function in a mouse model of synucleinopathy.
Franziska Richter, Sheila M Fleming, Melanie Watson, Vincent Lemesre, Lee Pellegrino, David J Lockhart

Neurotherapeutics· October 2014

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Racial disparity in the 30-day morbidity and mortality after surgery for endometrial cancer.
Haider Mahdi, David Lockhart, Mehdi Moslemi-Kebria, Peter G Rose

Gynecol Oncol· September 2014

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Surgical site infection in women undergoing surgery for gynecologic cancer.
Haider Mahdi, Anar Gojayev, Megan Buechel, Jason Knight, Janice SanMarco, David Lockhart

Int J Gynecol Cancer· May 2014

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Computerized counseling reduces HIV-1 viral load and sexual transmission risk: findings from a randomized controlled trial.
Ann E Kurth, Freya Spielberg, Charles M Cleland, Barrot Lambdin, David R Bangsberg, David Lockhart

J Acquir Immune Defic Syndr· April 2014

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Risk of death in heart disease is associated with elevated urinary globotriaosylceramide.
Raphael Schiffmann, Sabrina Forni, Caren Swift, Nastry Brignol, Xiaoyang Wu, David J Lockhart

J Am Heart Assoc· February 2014

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Prevalence and prognostic impact of lymphadenectomy and lymph node metastasis in clinically early-stage ovarian clear cell carcinoma.
Haider Mahdi, Mehdi Moslemi-Kebria, Kimberly L Levinson, Anar Gojayev, David Lockhart

Int J Gynecol Cancer· September 2013

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