Publications by authors named "David Lubkowicz"

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Rational Engineering of Nissle 1917 as Live Biotherapeutic to Degrade Uremic Toxin Precursors.
David Lubkowicz, David L Hava, Kim Lewis, Vincent M Isabella

ACS Synth Biol· April 2024

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The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers.
Mylène Perreault, Jillian Means, Erik Gerson, Michael James, Sean Cotton, David Lubkowicz

Cell Host Microbe· March 2024

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An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria.
David Lubkowicz, Nicholas G Horvath, Michael J James, Pasquale Cantarella, Lauren Renaud

Mol Syst Biol· March 2022

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Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chip.
M Tyler Nelson, Mark R Charbonneau, Heidi G Coia, Mary J Castillo, Corey Holt, David Lubkowicz

Nat Commun· May 2021

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Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria.
Vincent M Isabella, Binh N Ha, Mary Joan Castillo, David J Lubkowicz, Sarah E Rowe

Nat Biotechnol· October 2018

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Reprogramming Probiotic Lactobacillus reuteri as a Biosensor for Staphylococcus aureus Derived AIP-I Detection.
David Lubkowicz, Chun Loong Ho, In Young Hwang, Wen Shan Yew, Yung Seng Lee

ACS Synth Biol· May 2018

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Transplantability of a circadian clock to a noncircadian organism.
Anna H Chen, David Lubkowicz, Vivian Yeong, Roger L Chang, Pamela A Silver

Sci Adv· January 2015

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