Publications by authors named "David M Engman"

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Efficacy of benznidazole delivery during Chagas disease nanotherapy is dependent on the nanocarrier morphology.
Debora B Scariot, Austeja Staneviciute, Rayanne R B Machado, Simseok A Yuk, Yu-Gang Liu, David M Engman

Biomaterials· November 2025

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Dual Treatment of Chronic Chagasic Cardiomyopathy and Parasitic Burden via Combination Nanotherapy.
Austeja Staneviciute, Debora B Scariot, Yu-Gang Liu, Yuan Qian, Swagat Sharma, David M Engman

ACS Nano· May 2025

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Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?
Debora B Scariot, Austeja Staneviciute, Jennifer Zhu, Xiaomo Li, Evan A Scott, David M Engman

Front Cell Infect Microbiol· October 2022

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Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity.
Robert W B Brown, Aabha I Sharma, Miguel Rey Villanueva, Xiaomo Li, Ouma Onguka, David M Engman

Pathogens· October 2022

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Repurposing Carvedilol as a Novel Inhibitor of the Autophagy Flux That Affects Parasite Replication and Survival.
Cynthia Vanesa Rivero, Santiago José Martínez, Paul Novick, Juan Agustín Cueto, Betiana Nebaí Salassa, David M Engman

Front Cell Infect Microbiol· October 2021

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Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy.
Santiago J Martinez, Patricia S Romano, David M Engman

Front Cell Infect Microbiol· June 2021

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Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection.
Xiaomo Li, Sijia Yi, Débora B Scariot, Santiago J Martinez, Ben A Falk, David M Engman

JCI Insight· May 2021

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TMPRSS2 activity may mediate sex differences in COVID-19 severity.
Derick Okwan-Duodu, Eun-Cheon Lim, Sungyong You, David M Engman

Signal Transduct Target Ther· March 2021

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Comparison of Large, Medium, and Small Solid Tumor Gene Panels for Detection of Clinically Actionable Mutations in Cancer.
Eric Vail, Jianbo Song, Jing Xu, Joseph S Frye, Jong Taek Kim, David M Engman

Target Oncol· August 2020

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Protein Composition Reflects Extracellular Vesicle Heterogeneity.
Tatyana Vagner, Andrew Chin, Javier Mariscal, Serguei Bannykh, David M Engman

Proteomics· April 2019

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Carcinoid tumors of the thymus and Cushing's syndrome: Clinicopathologic features and current best evidence regarding the cell of origin of these unusual neoplasms.
Ann E Walts, Joseph Frye, David M Engman, Alberto M Marchevsky

Ann Diagn Pathol· February 2019

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Pathology and Pathogenesis of Chagas Heart Disease.
Kevin M Bonney, Daniel J Luthringer, Stacey A Kim, Nisha J Garg, David M Engman

Annu Rev Pathol· January 2019

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Cell Cycle Inhibition To Treat Sleeping Sickness.
Conrad L Epting, Brian T Emmer, Nga Y Du, Joann M Taylor, Ming Y Makanji, David M Engman

mBio· September 2017

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Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts.
Aabha I Sharma, Cheryl L Olson, João I Mamede, Felipe Gazos-Lopes, Conrad L Epting, David M Engman

Sci Rep· August 2017

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The Lipid Raft Proteome of African Trypanosomes Contains Many Flagellar Proteins.
Aabha I Sharma, Cheryl L Olson, David M Engman

Pathogens· August 2017

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Dynamic protein S-palmitoylation mediates parasite life cycle progression and diverse mechanisms of virulence.
Robert W B Brown, Aabha I Sharma, David M Engman

Crit Rev Biochem Mol Biol· April 2017

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Sphingosine Kinase Regulates Microtubule Dynamics and Organelle Positioning Necessary for Proper G1/S Cell Cycle Transition in Trypanosoma brucei.
Deborah A Pasternack, Aabha I Sharma, Cheryl L Olson, Conrad L Epting, David M Engman

mBio· October 2015

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Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead.
Kevin M Bonney, David M Engman

Am J Pathol· June 2015

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Calcium-dependent membrane association of a flagellar calcium sensor does not require calcium binding.
Danijela Maric, Cheryl L Olson, Xianzhong Xu, James B Ames, David M Engman

Mol Biochem Parasitol· May 2015

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Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease.
Kevin M Bonney, Joann M Taylor, Edward B Thorp, Conrad L Epting, David M Engman

Parasitol Res· March 2015

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Endothelial transmigration by Trypanosoma cruzi.
Bria M Coates, David P Sullivan, Ming Y Makanji, Nga Y Du, Cheryl L Olson, David M Engman

PLoS One· August 2014

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Acylation in trypanosomatids: an essential process and potential drug target.
Amanda M Goldston, Aabha I Sharma, Kimberly S Paul, David M Engman

Trends Parasitol· July 2014

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Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction.
Elaine Wan, Xin Yi Yeap, Shirley Dehn, Rachael Terry, Margaret Novak, David M Engman

Circ Res· September 2013

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(1)H, (15)N, and (13)C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
Xianzhong Xu, Cheryl L Olson, David M Engman, James B Ames

Biomol NMR Assign· April 2013

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NMR structure of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei.
Xianzhong Xu, Cheryl L Olson, David M Engman, James B Ames

Protein Sci· December 2012

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