Publications by authors named "David M Ryba"

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Signaling pathway alterations in hearts of a porcine model harboring a β-myosin heavy chain (MYH7-R403Q) gene variant.
Chad M Warren, David M Ryba, Gail E Geist, Aileen Castro Coronado, Beata M Wolska

J Mol Cell Cardiol Plus· December 2025

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A Laing distal myopathy-associated proline substitution in the β-myosin rod perturbs myosin cross-bridging activity.
Massimo Buvoli, Genevieve Ck Wilson, Ada Buvoli, Jack F Gugel, Abbi Hau, David M Ryba

J Clin Invest· May 2024

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A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.
Tomoya Sakamoto, Timothy R Matsuura, Shibiao Wan, David M Ryba, J Unil Kim

Circ Res· June 2020

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Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response.
Shamim A K Chowdhury, Chad M Warren, Jillian N Simon, David M Ryba, Ashley Batra

Front Physiol· March 2020

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Sphingosine-1-Phosphate Receptor Modulator, FTY720, Improves Diastolic Dysfunction and Partially Reverses Atrial Remodeling in a Tm-E180G Mouse Model Linked to Hypertrophic Cardiomyopathy.
David M Ryba, Chad M Warren, Chehade N Karam, Robert T Davis, Shamim A K Chowdhury

Circ Heart Fail· November 2019

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Long-Term Biased β-Arrestin Signaling Improves Cardiac Structure and Function in Dilated Cardiomyopathy.
David M Ryba, Jieli Li, Conrad L Cowan, Brenda Russell, Beata M Wolska

Circulation· March 2017

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N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy.
Tanganyika Wilder, David M Ryba, David F Wieczorek, Beata M Wolska, R John Solaro

Am J Physiol Heart Circ Physiol· November 2015

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Omecamtiv Mecarbil, a Cardiac Myosin Activator, Increases Ca2+ Sensitivity in Myofilaments With a Dilated Cardiomyopathy Mutant Tropomyosin E54K.
Megan S Utter, David M Ryba, Betty H Li, Beata M Wolska, R John Solaro

J Cardiovasc Pharmacol· October 2015

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Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model.
Madhusudhan Tarigopula, Robert T Davis, Paul T Mungai, David M Ryba, David F Wieczorek

Cardiovasc Res· July 2015

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