Publications by authors named "David M Tellers"

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Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships.
Michael A Plotkin, Marc Labroli, Jeffrey Schubert, Anthony Shaw, Kelly-Ann S Schlegel, David M Tellers

ACS Med Chem Lett· August 2024

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Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na1.7 for the Treatment of Pain.
Gregory L Adams, Parul S Pall, Steven M Grauer, Xiaoping Zhou, Jeanine E Ballard, David M Tellers

J Med Chem· January 2022

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The PET tracer [C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Wenping Li, Yuchuan Wang, Talakad G Lohith, Zhizhen Zeng, Ling Tong, David M Tellers

Sci Transl Med· January 2022

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Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.
Robert P Hayes, Mee Ra Heo, Mark Mason, John Reid, Christine Burlein, David M Tellers

Nat Commun· May 2021

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Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
Marina Bukhtiyarova, Erica M Cook, Paula J Hancock, Alan W Hruza, Anthony W Shaw, David M Tellers

ACS Med Chem Lett· January 2021

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Novel pH Selective, Highly Lytic Peptides Based on a Chimeric Influenza Hemagglutinin Peptide/Cell Penetrating Peptide Motif.
Bethany Algayer, Ann O'Brien, Aaron Momose, Dennis J Murphy, William Procopio, David M Tellers

Molecules· May 2019

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Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions.
Daniel Zewge, Gabor Butora, Edward C Sherer, David M Tellers, Daniel R Sidler

Bioconjug Chem· June 2018

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Computational design and experimental characterization of peptides intended for pH-dependent membrane insertion and pore formation.
Yao Zhang, René Bartz, Gevorg Grigoryan, Michael Bryant, Jeff Aaronson, David M Tellers

ACS Chem Biol· April 2015

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High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation.
Daniel Zewge, Francis Gosselin, Denise M Kenski, Jenny Li, Vasant Jadhav, David M Tellers

Bioconjug Chem· December 2014

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Molecular umbrella conjugate for the ocular delivery of siRNA.
Vaclav Janout, Lauren L Cline, Bradley P Feuston, Lee Klein, Ann O'Brien, David M Tellers

Bioconjug Chem· February 2014

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Synthesis of vaniprevir (MK-7009): lactamization to prepare a 20-membered [corrected] macrocycle.
Zhiguo J Song, David M Tellers, Michel Journet, Jeffrey T Kuethe, David Lieberman

J Org Chem· October 2011

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Rapid HATU-mediated solution phase siRNA conjugation.
Jeffrey G Aaronson, Lee J Klein, Aaron A Momose, Ann M O'Brien, Anthony W Shaw, David M Tellers

Bioconjug Chem· August 2011

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Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape.
René Bartz, Haihong Fan, Jingtao Zhang, Nathalie Innocent, Craig Cherrin, David M Tellers

Biochem J· April 2011

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On the mechanism of an asymmetric alpha,beta-unsaturated carboxylic acid hydrogenation: application to the synthesis of a PGD2 receptor antagonist.
David M Tellers, J Christopher McWilliams, Guy Humphrey, Michel Journet, Lisa DiMichele

J Am Chem Soc· December 2006

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Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives.
Norihiro Ikemoto, David M Tellers, Spencer D Dreher, Jinchu Liu, Angie Huang

J Am Chem Soc· March 2004

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A [2 + 2] cycloaddition route to dimethylaminomethylene vinamidinium salts.
Ian W Davies, David M Tellers, C Scott Shultz, Fred J Fleitz, Dongwei Cai

Org Lett· August 2002

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Electronic and medium effects on the rate of arene C [bond] H activation by cationic Ir(III) complexes.
David M Tellers, Cathleen M Yung, Bruce A Arndtsen, Dan R Adamson, Robert G Bergman

J Am Chem Soc· February 2002

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Synthesis of Iridium(III) Carboxamides via the Bimetallic Reaction between Cp(PMe(3))IrPh(OH) and [Cp(PMe(3))Ir(Ph)NCR](+).
David M. Tellers, Joachim C. M. Ritter, Robert G. Bergman

Inorg Chem· October 1999

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