Publications by authors named "David Malwitz"

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Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.
Paul E Harrington, Kaustav Biswas, David Malwitz, Andrew S Tasker, Christopher Mohr

ACS Med Chem Lett· January 2015

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Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.
Jeroen C Verheijen, David J Richard, Kevin Curran, Joshua Kaplan, Mark Lefever, David J Malwitz

J Med Chem· December 2009

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Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.
Pawel Nowak, Derek C Cole, Natasja Brooijmans, Matthew G Bursavich, Kevin J Curran, David J Malwitz

J Med Chem· November 2009

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Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.
Ker Yu, Lourdes Toral-Barza, Celine Shi, Wei-Guo Zhang, Judy Lucas, David J Malwitz

Cancer Res· August 2009

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ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines.
Arie Zask, Jeroen C Verheijen, Kevin Curran, Joshua Kaplan, David J Richard, David J Malwitz

J Med Chem· August 2009

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