Publications by authors named "David Mankoff"

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Creating a dedicated radionuclide therapy clinic and leveraging telemedicine to increase access to radiopharmaceutical therapies.
Sophia R O'Brien, Austin R Pantel, Neil Taunk, David Mankoff, Daniel Gray

Clin Imaging· January 2026

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Safety of the Combination of External Beam Radiotherapy with Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer.
Abigail Pepin, Abigail Doucette, Neha Vapiwala, Vivek K Narayan, Samuel U Takvorian, David A Mankoff

J Nucl Med· December 2025

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Early assessment of treatment response in AML using FLT PET/cT: a trial of the ECOG-ACRIN Cancer Research Group (EAI141).
Robert Jeraj, Fenghai Duan, Ryan J Mattison, Justin Romanoff, Lale Kostakoglu, David A Mankoff

Leuk Lymphoma· December 2025

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Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy.
Amulya Sreekumar, Eric Blankemeyer, Christopher J Sterner, Tien-Chi Pan, Dhruv K Pant, David A Mankoff

Cancer Discov· December 2025

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L-5-[C]-glutamine PET of breast cancer: Preclinical studies in mouse models.
Christopher T Hensley, Prashanth Padakanti, Raheema Damani, Christina Dulal, Hoon Choi, David Mankoff

Nucl Med Biol· November 2025

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EA1211: interim FDG-PET/CT for predicting response of HER2-positive breast cancer to neoadjuvant therapy (DIRECT trial).
Maeve A Hennessy, Constantine Gatsonis, Heather Jacene, Roisin M Connolly, Brian L Burnette, David A Mankoff

Future Oncol· November 2025

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First-in-Human Biodistribution and Dosimetry of [C]Trimethoprim.
Anthony J Young, Robert K Doot, Joshua K Cho, Jonathan M Pham, Alvaro A Ordonez, David A Mankoff

Mol Imaging Biol· November 2025

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Novel 4D radiomics applied to dynamic FES PET images to improve prediction of breast cancer response to ER-targeted therapy.
Andrew William Chen, Carla R Zeballos Torrez, Lanell M Peterson, Mark Muzi, Jennifer M Specht, David A Mankoff

Eur J Nucl Med Mol Imaging· November 2025

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Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [F]FGln and [F]FDG.
Daniel Kwon, Elizabeth J Li, Christina Dulal, Margaret Daube-Witherspoon, Varsha Viswanath, David A Mankoff

J Nucl Med· July 2025

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Funding Reductions Threaten the Future of Medical Innovation.
Johannes Czernin, Carolyn J Anderson, Ramsey Derek Badawi, Henryk Barthel, Frank M Bengel, David A Mankoff

J Nucl Med· June 2025

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[18 F]-Fluoroestradiol PET (FES-PET) and [18 F] Flurodeoxyglucose PET (FDG-PET) Imaging May Aid in Managing Therapy in Patients with Metastatic Lobular Breast Cancer.
Poorni M Manohar, Lanell M Peterson, Isaac C Jenkins, Qian Vicky Wu, Brenda F Kurland, David A Mankoff

Mol Imaging Biol· June 2025

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Negative 18F-FES PET/CT Despite Estrogen Receptor Positivity by Immunohistochemistry.
Ismaheel O Lawal, Xiaoxian Li, Elizabeth A Sakach, Clara R Farley, Jane L Meisel, David A Mankoff

Clin Nucl Med· June 2025

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Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy.
Amulya Sreekumar, Eric Blankemeyer, Christopher J Sterner, Tien-Chi Pan, Dhruv K Pant, David A Mankoff

bioRxiv· May 2025

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Upstaging of Invasive Lobular Cancer With FES PET/CT.
Saud Rehman, Christine E Edmonds, David A Mankoff, Austin R Pantel, Sophia R O'Brien

Clin Nucl Med· March 2025

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Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export.
Hoon Choi, Mamta Gupta, Arjun Sengupta, Emma E Furth, Christopher Hensley, David Mankoff

Neoplasia· March 2025

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Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence.
Elizabeth S McDonald, Tien-Chi Pan, Dhruv K Pant, Melissa A Troester, Andrew V Kossenkov, David A Mankoff

Cancer Res Commun· February 2025

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Fluoroestradiol (FES) and Fluorodeoxyglucose (FDG) PET imaging in patients with ER+, HER2-positive or HER2-negative metastatic breast cancer.
Natasha B Hunter, Lanell M Peterson, Jennifer M Specht, David A Mankoff, Mark Muzi

Breast Cancer Res· February 2025

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[F]Fluorthanatrace PET in Ovarian Cancer: Comparison with [F]FDG PET, Lesion Location, Tumor Grade, and Breast Cancer Gene Mutation Status.
Joanna K Weeks, Austin R Pantel, Sarah B Gitto, Fang Liu, Erin K Schubert, David A Mankoff

J Nucl Med· January 2025

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Optimizing Regulatory Reviews for Clinical Protocols That Use Radiopharmaceuticals: Findings of the University of Pennsylvania Radiation Research Safety Committee.
Sylvia S Rhodes, Janelle E Jesikiewicz, Nikhil Yegya-Raman, Kavya Prasad, Alexandra Dreyfuss, David A Mankoff

Health Phys· December 2024

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Kinetic Analysis and Metabolism of Poly(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted F-Fluorthanatrace PET in Breast Cancer.
Anthony J Young, Austin R Pantel, Mahsa Kiani, Robert K Doot, Sina Bagheri, David A Mankoff

J Nucl Med· December 2024

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Update on F-Fluoroestradiol.
Sophia R O'Brien, Christine E Edmonds, Rebecca E Ward, Neil K Taunk, Austin R Pantel, David A Mankoff

Semin Nucl Med· November 2024

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PET Imaging of Breast Cancer: Current Applications and Future Directions.
Christine E Edmonds, Sophia R O'Brien, Elizabeth S McDonald, David A Mankoff, Austin R Pantel

J Breast Imaging· November 2024

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No In Vivo Evidence for Estrogen Receptor Density Changes in Human Neuroendocrine Aging or Their Relationship to Cognition and Menopausal Symptoms.
Anat Biegon, William Jagust, David A Mankoff

J Nucl Med· November 2024

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Coronary Microvascular Dysfunction in Men with Prostate Cancer Receiving Androgen-Deprivation Therapy.
Erin Welch, Marie A Guerraty, Biniyam G Demissei, Naomi Haas, Samuel Takvorian, David A Mankoff

Clin Genitourin Cancer· August 2024

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16α-18F-Fluoro-17β-Estradiol PET/CT-A Tool for Staging Estrogen Receptor-Expressing Breast Cancer?
Sophia R O'Brien, Austin R Pantel, David A Mankoff

JAMA Netw Open· July 2024

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