Publications by authors named "David Matallanas"

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Assessment of the molecular mechanisms of drug-induced hidden cardiotoxicity by a multi-omics approach: The example of rofecoxib.
Bennet Y Weber, Gábor B Brenner, Barnabás Váradi, Bence Ágg, Csenger Kovácsházi, David Matallanas

Br J Pharmacol· October 2025

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Single- vs. Multi-Walled Carbon Nanotubes: Differential Cellular Stress and Lipid Metabolism Effects in Macrophage Models.
Sara Nahle, Hilary Cassidy, David Matallanas, Bertrand H Rihn, Olivier Joubert

Nanomaterials (Basel)· September 2025

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Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett's oesophagus compared to monounsaturated fat, particularly in contrast to oesophageal adenocarcinoma.
Kathleen A J Mitchelson, Fiona O'Connell, Kieran Wynne, David Matallanas, Jacintha O'Sullivan

Neoplasia· August 2025

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Optimized network inference for immune diseased single cells.
Elena Merino Tejero, Dwain Jude Vaz, Guillermo Barturen, María Rivas-Torrubia, Marta E Alarcón-Riquelme, David Matallanas

Front Immunol· August 2025

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Effects of ALS-associated 5'tiRNA on the transcriptomic and proteomic profile of primary neurons in vitro.
Elisabeth Jirström, Anna Matveeva, Sharada Baindoor, Paul Donovan, Qilian Ma, David Matallanas

Exp Neurol· March 2025

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A Novel Role for FERM Domain-Containing Protein 3 in CKD.
Ciarán Kennedy, Ross Doyle, Oisin Gough, Caitriona Mcevoy, Susan McAnallen, David Matallanas

Kidney360· December 2024

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Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles.
Csenger Kovácsházi, Szabolcs Hambalkó, Nabil V Sayour, Tamás G Gergely, Gábor B Brenner, David Matallanas

Sci Rep· May 2024

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Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.
Anna Matveeva, Orla Watters, Ani Rukhadze, Niraj Khemka, Debora Gentile, David Matallanas

Amyotroph Lateral Scler Frontotemporal Degener· February 2024

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Multiple Myeloma Derived Extracellular Vesicle Uptake by Monocyte Cells Stimulates IL-6 and MMP-9 Secretion and Promotes Cancer Cell Migration and Proliferation.
Rebecca Sheridan, Kieran Brennan, Despina Bazou, Peter O'Gorman, David Matallanas

Cancers (Basel)· February 2024

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Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes.
Husvinee Sundaramurthi, Valentina Tonelotto, Kieran Wynne, Fiona O'Connell, Eve O'Reilly, David Matallanas

Open Res Eur· November 2023

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Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib.
Aoife Nolan, Cinzia Raso, Walter Kolch, Alex von Kriegsheim, Kieran Wynne, David Matallanas

Cancers (Basel)· August 2023

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Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis.
Rebecca L Gorry, Kieran Brennan, Paul T M Lavin, Tayler Mazurski, Charline Mary, David Matallanas

Int J Mol Sci· July 2023

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Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma.
David Romano, Lucía García-Gutiérrez, Nourhan Aboud, David J Duffy, Keith T Flaherty, David Matallanas

Life Sci Alliance· October 2022

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Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis· August 2022

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Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma.
Simone Marcone, Amy Buckley, Colm J Ryan, Mark McCabe, Niamh Lynam-Lennon, David Matallanas

Cancer Treat Res Commun· December 2021

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An Investigation into Proteomic Constituents of Cerebrospinal Fluid in Patients with Chronic Peripheral Neuropathic Pain Medicated with Opioids- a Pilot Study.
Jonathan Royds, Hilary Cassidy, Melissa J Conroy, Margaret R Dunne, David Matallanas

J Neuroimmune Pharmacol· September 2021

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Hidden Targets in RAF Signalling Pathways to Block Oncogenic RAS Signalling.
Aoife A Nolan, Nourhan K Aboud, Walter Kolch, David Matallanas

Genes (Basel)· April 2021

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Inhaled multi-walled carbon nanotubes differently modulate global gene and protein expression in rat lungs.
Carole Seidel, Vadim Zhernovkov, Hilary Cassidy, Boris Kholodenko, David Matallanas

Nanotoxicology· March 2021

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BAX and SMAC regulate bistable properties of the apoptotic caspase system.
Stephanie McKenna, Lucía García-Gutiérrez, David Matallanas, Dirk Fey

Sci Rep· February 2021

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The Ins and Outs of RAS Effector Complexes.
Christina Kiel, David Matallanas, Walter Kolch

Biomolecules· February 2021

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IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway.
Niall P Quinn, Lucía García-Gutiérrez, Carolanne Doherty, Alexander von Kriegsheim, Emma Fallahi, David Matallanas

Cells· February 2021

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Accurate prediction of kinase-substrate networks using knowledge graphs.
Vít Nováček, Gavin McGauran, David Matallanas, Adrián Vallejo Blanco, Piero Conca

PLoS Comput Biol· December 2020

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Resolving the Interactome of the Human Macrophage Immunometabolism Regulator (MACIR) with Enhanced Membrane Protein Preparation and Affinity Proteomics.
Gavin McGauran, Emma Dorris, Razvan Borza, Niamh Morgan, Denis C Shields, David Matallanas

Proteomics· October 2020

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Examination and characterisation of burst spinal cord stimulation on cerebrospinal fluid cellular and protein constituents in patient responders with chronic neuropathic pain - A Pilot Study.
Jonathan Royds, Melissa J Conroy, Margaret R Dunne, Hilary Cassidy, David Matallanas

J Neuroimmunol· July 2020

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Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis.
Zivile Useckaite, Mark P Ward, Anne Trappe, Rebecca Reilly, Jenny Lennon, David Matallanas

Thorax· June 2020

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