Publications by authors named "David McConkey"

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Clinicopathologic and Prognostic Features of Sarcomatoid Urothelial Carcinoma: A Retrospective Study of 136 Patients With Emphasis on Early-Stage (pT1) Disease.
Huili Li, Vamsi Parimi, Burles Johnson, Sonia Kamanda, Ezra Baraban, David J McConkey

Am J Surg Pathol· January 2026

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Intermediate-risk Non-muscle-invasive Bladder Cancer: Recommendations for Definitions, Risk Stratification, Management Strategies, and Clinical Trial Design from the International Bladder Cancer Group.
Roger Li, Patrick J Hensley, Marko Babjuk, Laura Bukavina, Sarah P Psutka, David J McConkey

Eur Urol Oncol· December 2025

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The Bladder Tumor Microenvironment Is a Dynamic Ecosystem: How Microbes, Immunity, and Cancer Converge.
David J McConkey, Jennifer J Barb, Armine K Smith, Michael L Neugent

Eur Urol· December 2025

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Dynamics of Tumor-informed Circulating Tumor DNA and Association with Clinical Responses to Enfortumab and Pembrolizumab in Patients with Locally Advanced or Metastatic Urothelial Carcinoma.
Evangelia Vlachou, Burles Avner Johnson, Max Kates, Nirmish Singla, Sunil Patel, David McConkey

Eur Urol· December 2025

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Urine Tumor DNA to Stratify the Risk of Recurrence in Patients Treated with Atezolizumab for Bacillus Calmette-Guérin-unresponsive Non-muscle-invasive Bladder Cancer.
Marie-Pier St-Laurent, Parminder Singh, David J McConkey, M Scott Lucia, Vadim S Koshkin

Eur Urol· November 2025

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Molecular classification of nonurothelial histologic subtypes of bladder cancer.
Michelle I Higgins, Andrew T Gabrielson, Zhuo Tony Su, Mingxiao Feng, Gabriel Epstein, David J McConkey

Urol Oncol· November 2025

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Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer.
Sangkyou Lee, Sung Yun Jung, Pawel Kuś, Jolanta Bondaruk, June Goo Lee, David McConkey

J Pathol· November 2025

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T cell subsets of urine-derived lymphocytes (UDLs) serve as an indicator of TILs and reflect immunological sex differences in bladder cancer.
Johanna M Schafer, No-Joon Song, Tong Xiao, Timothy D Gauntner, Kyeong Joo Jung, David McConkey

J Immunother Cancer· October 2025

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Intratumoral expression of a composite B cell / CD8 T cell biomarker stratifies overall survival by ctDNA status and benefit from adjuvant immunotherapy in high risk, muscle invasive urothelial carcinoma.
Roy Elias, Adam K Aragaki, Jean H Hoffman-Censits, Noah M Hahn, David J McConkey

J Urol· October 2025

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Novel Pretreatment Autoantibodies Correlate with Enfortumab Vedotin-Related Dermatologic Events in Patients with Advanced Urothelial Cancer.
Evangelia Vlachou, Burles A Johnson, David J McConkey, Noah M Hahn, Yuezhou Jing

Cancer Res Commun· September 2025

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A festschrift in honor of Ian M. Thompson Jr., MD.
Robert S Svatek, Donna P Ankerst, Anthony V D' Amico, Thomas W Flaig, Leslie G Ford, David J McConkey

Urol Oncol· July 2025

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Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601.
Gopa Iyer, Woonyoung Choi, Bin Luo, Filipe Carvalho, Timothy Hanlon, David J McConkey

JCO Precis Oncol· July 2025

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Metabolic landscape in bladder cancer.
Syrus Razavi, Amir Khan, De-Xue Fu, Dirk Mayer, David McConkey

Curr Opin Oncol· May 2025

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Minimal Residual Disease Detection with Urine-derived DNA Is Prognostic for Recurrence-free Survival in Bacillus Calmette-Guérin-unresponsive Non-muscle-invasive Bladder Cancer Treated with Nadofaragene Firadenovec.
Vikram M Narayan, Come Tholomier, Sharada Mokkapati, Alberto Martini, Vincent M Caruso, David J McConkey

Eur Urol Oncol· April 2025

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Integrating gene therapy into the treatment paradigm for non-muscle invasive bladder cancer.
Alexis R Steinmetz, Behzad Jazayeri, Morgan Pierce, Sharada Mokkapati, David McConkey

Expert Opin Biol Ther· April 2025

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Sarcomatoid areas of urothelial carcinoma are enriched for CD163-positive antigen-presenting cells.
Burles A Johnson, Vamsi Parimi, Sonia Kamanda, David C Corney, Woonyoung Choi, David J McConkey

J Pathol Clin Res· March 2025

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Predicting response to neoadjuvant chemotherapy in muscle-invasive bladder cancer via interpretable multimodal deep learning.
Zilong Bai, Mohamed Osman, Matthew Brendel, Catherine M Tangen, Thomas W Flaig, David J McConkey

NPJ Digit Med· March 2025

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Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.
Sharada Mokkapati, Ganiraju Manyam, Alexis R Steinmetz, Côme Tholomier, Alberto Martini, David J McConkey

Transl Oncol· February 2025

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Summary from the NCI clinical trials planning meeting on next generation of clinical trials in non-muscle invasive bladder cancer.
Andrea Apolo, Brian C Baumann, Hikmat Al-Ahmadie, Leslie Ballas, Rick Bangs, David McConkey

Bladder Cancer· February 2025

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YAP1 induces bladder cancer progression and promotes immune evasion through IL-6/STAT3 pathway and CXCL deregulation.
Pritam Sadhukhan, Mingxiao Feng, Emily Illingworth, Ido Sloma, Akira Ooki, David McConkey

J Clin Invest· December 2024

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Microbiome-based Therapeutics: Cutting-edge Innovation or Perpetual Promise?
David J McConkey, Jennifer J Barb, Armine K Smith, Cynthia L Sears

Eur Urol Focus· December 2024

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NECTIN-4 PET FOR OPTIMIZING ENFORTUMAB VEDOTIN DOSE-RESPONSE IN UROTHELIAL CARCINOMA.
Akhilesh Mishra, Ajay Kumar Sharma, Kuldeep Gupta, Dhanush R Banka, Burles A Johnson, David J McConkey

bioRxiv· December 2024

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DNA Damage Response Alterations Predict for Neoadjuvant Chemotherapy Sensitivity in Muscle-Invasive Bladder Cancer: A Correlative Analysis of the SWOG S1314 Trial.
Gopa Iyer, Catherine M Tangen, Michal Sarfaty, Ashley M Regazzi, I-Ling Lee, David J McConkey

JCO Precis Oncol· November 2024

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Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.
Alexis R Steinmetz, Morgan Pierce, Alberto Martini, Come Tholomier, Ganiraju Manyam, David J McConkey

Front Immunol· November 2024

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Circulating Tumor Cell Count and Overall Survival in Patients With Metastatic Hormone-Sensitive Prostate Cancer.
Amir Goldkorn, Catherine Tangen, Melissa Plets, Daniel Bsteh, Tong Xu, David James McConkey

JAMA Netw Open· October 2024

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