Publications by authors named "David Meierhofer"

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Multiomics approach identifies SERPINB1 as candidate biomarker for spinocerebellar ataxia type 2.
Luis E Almaguer-Mederos, Jana Key, Nesli-Ece Sen, Julia Canet-Pons, Claudia Döring, David Meierhofer

Sci Rep· November 2025

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Conditional ATXN2L-Null in Adult Frontal Cortex CamK2a+ Neurons Does Not Cause Cell Death but Restricts Spontaneous Mobility and Affects the Alternative Splicing Pathway.
Jana Key, Luis-Enrique Almaguer-Mederos, Arvind Reddy Kandi, Meike Fellenz, Suzana Gispert, David Meierhofer

Cells· September 2025

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Probing condensate microenvironments with a micropeptide killswitch.
Yaotian Zhang, Ida Stöppelkamp, Pablo Fernandez-Pernas, Melanie Allram, Matthew Charman, David Meierhofer

Nature· July 2025

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ATXN2L primarily interacts with NUFIP2, the absence of ATXN2L results in NUFIP2 depletion, and the ATXN2-polyQ expansion triggers NUFIP2 accumulation.
Jana Key, Luis-Enrique Almaguer-Mederos, Arvind Reddy Kandi, Nesli-Ece Sen, Suzana Gispert, David Meierhofer

Neurobiol Dis· June 2025

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Quantifying Flavin mononucleotide: an internationally validated methodological approach for enhanced decision making in organ transplantation.
Keyue Sun, Chunbao Jiao, Rebecca Panconesi, Sangeeta Satish, Omer F Karakaya, David Meierhofer

EBioMedicine· June 2025

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Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases.
Johanna Luige, Thomas Conrad, Alexandros Armaos, Annita Louloupi, Anna Vincent, David Meierhofer

Comput Struct Biotechnol J· June 2025

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Assessment of liver graft quality during hypothermic oxygenated perfusion: The first international validation study.
Jahnina Eden, Adam M Thorne, Silke B Bodewes, Damiano Patrono, Dorotea Roggio, David Meierhofer

J Hepatol· March 2025

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Golgi pH elevation due to loss of V-ATPase subunit V0a2 function correlates with tissue-specific glycosylation changes and globozoospermia.
Johannes Kopp, Denise Jahn, Guido Vogt, Anthi Psoma, Edoardo Ratto, David Meierhofer

Cell Mol Life Sci· December 2024

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SRF promotes long-range chromatin loop formation and stem cell pluripotency.
Pavel Tsaytler, Gaby Blaess, Manuela Scholze-Wittler, David Meierhofer, Lars Wittler

Cell Rep· October 2024

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Pregnancy alters fatty acid metabolism, glucose regulation, and detoxification of the liver in synchrony with biomechanical property changes.
Jing Guo, Karolina Krehl, Yasmine Safraou, Iwona Wallach, Jürgen Braun, David Meierhofer

Heliyon· October 2024

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Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, David Meierhofer

Nat Commun· August 2024

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Uncovering the dynamics and consequences of RNA isoform changes during neuronal differentiation.
Jelena Ulicevic, Zhihao Shao, Olga Jasnovidova, Annkatrin Bressin, Martyna Gajos, David Meierhofer

Mol Syst Biol· July 2024

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Protein translation rate determines neocortical neuron fate.
Ekaterina Borisova, Andrew G Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, David Meierhofer

Nat Commun· June 2024

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N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules.
Pavel Kudrin, Ankita Singh, David Meierhofer, Anna Kuśnierczyk, Ulf Andersson Vang Ørom

EMBO Rep· April 2024

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FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy.
Vera A van der Weijden, Maximilian Stötzel, Dhanur P Iyer, Beatrix Fauler, Elzbieta Gralinska, David Meierhofer

Nat Cell Biol· February 2024

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Disrupted degradative sorting of TLR7 is associated with human lupus.
Harshita Mishra, Claire Schlack-Leigers, Ee Lyn Lim, Oliver Thieck, Thomas Magg, David Meierhofer

Sci Immunol· February 2024

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Autonomous transposons tune their sequences to ensure somatic suppression.
İbrahim Avşar Ilık, Petar Glažar, Kevin Tse, Björn Brändl, David Meierhofer

Nature· February 2024

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CLPP-Null Eukaryotes with Excess Heme Biosynthesis Show Reduced L-arginine Levels, Probably via CLPX-Mediated OAT Activation.
Jana Key, Suzana Gispert, Arvind Reddy Kandi, Daniela Heinz, Andrea Hamann, David Meierhofer

Biomolecules· February 2024

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Screening for mitochondrial function before use-routine liver assessment during hypothermic oxygenated perfusion impacts liver utilization.
Janina Eden, Eva Breuer, Dominique Birrer, Matteo Müller, Matthias Pfister, David Meierhofer

EBioMedicine· December 2023

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Mitochondrial injury during normothermic regional perfusion (NRP) and hypothermic oxygenated perfusion (HOPE) in a rodent model of DCD liver transplantation.
Rebecca Panconesi, Mauricio Flores Carvalho, Janina Eden, Marilena Fazi, Fariha Ansari, David Meierhofer

EBioMedicine· December 2023

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Rational optimization of a transcription factor activation domain inhibitor.
Shaon Basu, Paula Martínez-Cristóbal, Marta Frigolé-Vivas, Mireia Pesarrodona, Michael Lewis, David Meierhofer

Nat Struct Mol Biol· December 2023

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Reverse genetic screening during L1 arrest reveals a role of the diacylglycerol kinase 1 gene dgk-1 and sphingolipid metabolism genes in sleep regulation.
Anastasios Koutsoumparis, Inka Busack, Chung-Kuan Chen, Yu Hayashi, Bart P Braeckman, David Meierhofer

Genetics· October 2023

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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Paul T Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A Turner, Inmaculada Márquez, David Meierhofer

Nat Commun· July 2023

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Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A Ilik, David Meierhofer

Nat Cell Biol· April 2023

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is a transiently expressed non-coding RNA essential for human endoderm formation.
Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer, Christian Much, René Buschow, David Meierhofer

Elife· January 2023

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