Publications by authors named "David Micklem"

Claim this Profile
A
A phase 1b, multicentre, dose escalation, safety and pharmacokinetics study of tilvestamab (BGB149) in relapsed, platinum-resistant, high-grade serous ovarian cancer (PROC) patients.
Kenneth Sooi, Tuan Zea Tan, Jae-Weon Kim, Jung Yun Lee, Byoung-Gie Kim, David Micklem

Br J Cancer· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Paratope mapping of tilvestamab, an anti-AXL function-blocking antibody, using high-throughput bacterial expression of secreted scFv-osmY fusion proteins.
Eleni Christakou, Petri Kursula, David Micklem

Biosci Rep· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bemcentinib as monotherapy and in combination with low-dose cytarabine in acute myeloid leukemia patients unfit for intensive chemotherapy: a phase 1b/2a trial.
Sonja Loges, Michael Heuser, Jörg Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, David Micklem

Nat Commun· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AXL-TBK1 driven AKT3 activation promotes metastasis.
Emily N Arner, Dina Alzhanova, Jill M Westcott, Stefan Hinz, Crina Elena Tiron, David Micklem

Sci Signal· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AXL expression reflects tumor-immune cell dynamics impacting outcome in non-small cell lung cancer patients treated with immune checkpoint inhibitor monotherapy.
Austin Rayford, Fabian Gärtner, Maria P Ramnefjell, James B Lorens, David R Micklem

Front Immunol· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vivo turnover and biodistribution of soluble AXL: implications for biomarker development.
Olav Tenstad, Eleni Christakou, Linn Hodneland Nilsson, Gro Gausdal, David Micklem

Sci Rep· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phase 1 trial of bemcentinib (BGB324), a first-in-class, selective AXL inhibitor, with docetaxel in patients with previously treated advanced non-small cell lung cancer.
Sheena Bhalla, Farjana J Fattah, Chul Ahn, Jessica Williams, Alyssa Macchiaroli, David Micklem

Lung Cancer· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AXL targeting restores PD-1 blockade sensitivity of mutant NSCLC through expansion of TCF1 CD8 T cells.
Huiyu Li, Zhida Liu, Longchao Liu, Hongyi Zhang, Chuanhui Han, David Micklem

Cell Rep Med· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphatidylserine receptors enhance SARS-CoV-2 infection.
Dana Bohan, Hanora Van Ert, Natalie Ruggio, Kai J Rogers, Mohammad Badreddine, David Micklem

PLoS Pathog· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphatidylserine Receptors Enhance SARS-CoV-2 Infection: AXL as a Therapeutic Target for COVID-19.
Dana Bohan, Hanora Van Ert, Natalie Ruggio, Kai J Rogers, Mohammad Badreddine, David Micklem

bioRxiv· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells.
Maria L Lotsberg, Katarzyna Wnuk-Lipinska, Stéphane Terry, Tuan Zea Tan, Ning Lu, David Micklem

J Thorac Oncol· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology.
Linn Iren Hodneland Nilsson, Ina Katrine Nitschke Pettersen, Julie Nikolaisen, David Micklem, Hege Avsnes Dale

Sci Rep· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology.
Linn Iren Hodneland Nilsson, Ina Katrine Nitschke Pettersen, Julie Nikolaisen, David Micklem, Hege Avsnes Dale

Sci Rep· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.
Amanda Kirane, Kathleen F Ludwig, Noah Sorrelle, Gry Haaland, Tone Sandal, David Micklem

Cancer Res· September 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women.
Lavina Ahmed, Hawa Nalwoga, Jarle B Arnes, Henry Wabinga, David R Micklem

APMIS· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets.
David R Micklem, Magnus Blø, Petra Bergström, Erlend Hodneland, Crina Tiron

BMC Biotechnol· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model.
Jan Roger Olsen, Anne Margrete Oyan, Kari Rostad, Margrete R Hellem, Jie Liu, David R Micklem

PLoS One· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Contextual compound screening for improved therapeutic discovery.
Lasse Evensen, Kristin Odlo, David R Micklem, Amanda Littlewood-Evans, Jeanette Wood

Chembiochem· December 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.
Elisabeth Silden, Sigrun M Hjelle, Line Wergeland, André Sulen, Vibeke Andresen, David R Micklem

PLoS One· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer.
Emmet McCormack, Elisabeth Silden, Richard M West, Tina Pavlin, David R Micklem

Cancer Res· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficient in vivo vascularization of tissue-engineering scaffolds.
Anja Hegen, Anna Blois, Crina E Tiron, Monica Hellesøy, David R Micklem

J Tissue Eng Regen Med· April 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery.
Lasse Evensen, David R Micklem, Wolfgang Link, James B Lorens

Cytometry A· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Christine Gjerdrum, Crina Tiron, Torill Høiby, Ingunn Stefansson, Hallvard Haugen, David R Micklem

Proc Natl Acad Sci U S A· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome.
Francesco Parlati, Susan J Lee, Monette Aujay, Erika Suzuki, Konstantin Levitsky, David R Micklem

Blood· October 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mural cell associated VEGF is required for organotypic vessel formation.
Lasse Evensen, David R Micklem, Anna Blois, Sissel Vik Berge, Niels Aarsaether

PLoS One· June 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis