Publications by authors named "David Monroe"

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Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues.
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, Yeaeun Han, David G Monroe

EMBO J· December 2025

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Senescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow.
Xu Zhang, Madison L Doolittle, Ting Fan, Utkarsh Tripathi, Yan Er Ng, David G Monroe

Obesity (Silver Spring)· December 2025

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Towards a personalized approach in senolytic trials.
Sundeep Khosla, David G Monroe, Joshua N Farr

Nat Aging· October 2025

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Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats.
Abhishek Chandra, Zaira Aversa, Xu Zhang, Joshua N Farr, Achudhan David, David G Monroe

bioRxiv· September 2025

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Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus.
Caroline Hoong, Joshua N Farr, David G Monroe, Thomas A White, Elizabeth J Atkinson

Aging Cell· August 2025

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Impact of abortion bans on pregnancies with severe life-limiting foetal anomalies in the United States: a cost-effectiveness analysis.
David M Monroe, Megha Arora, Kimberley A Bullard, Aaron B Caughey

Eur J Contracept Reprod Health Care· June 2025

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Characterization of Human Senescent Cell Biomarkers for Clinical Trials.
Joshua N Farr, David G Monroe, Elizabeth J Atkinson, Mitchell N Froemming, Ming Ruan

Aging Cell· May 2025

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Pharmacogenetic and microRNA mechanisms of beta blocker use on bone.
Christine W Lary, Elizabeth J Atkinson, Jennifer Spillane, Zannatun Nayema, Tyler A Roy, David G Monroe

J Bone Miner Res· February 2025

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Isolation and characterization of bone mesenchymal cell small extracellular vesicles using a novel mouse model.
David G Monroe, Naureen Javeed, Jennifer L Rowsey, Ming Ruan, Chantal E McCabe

J Bone Miner Res· October 2024

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Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial.
Joshua N Farr, Elizabeth J Atkinson, Sara J Achenbach, Tammie L Volkman, Amanda J Tweed, David G Monroe

Nat Med· September 2024

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Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn L Kosinsky, David G Monroe

J Clin Invest· May 2024

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Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn L Kosinsky, David G Monroe

bioRxiv· February 2024

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Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.
Davis A Englund, Alyssa M Jolliffe, Gabriel J Hanson, Zaira Aversa, Xu Zhang, David G Monroe

JCI Insight· January 2024

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Distinct secretomes in p16- and p21- positive senescent cells across tissues.
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe

bioRxiv· December 2023

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Improving surgical wound classification accuracy through education and audit processes.
Hannah Fullington, Morgan Block, Nisha Jose, Stephanie Peschka, Jessica Brooks, David Monroe

BMJ Open Qual· November 2023

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Modest Effects of Osteoclast-Specific ERα Deletion after Skeletal Maturity.
Madison L Doolittle, Brittany A Eckhardt, Stephanie J Vos, Sarah Grain, Jennifer L Rowsey, David G Monroe

JBMR Plus· October 2023

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Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization.
Michael J Emch, Zofia Wicik, Kirsten G M Aspros, Tanja Vukajlovic, Kevin S Pitel, David G Monroe

Mol Ther Nucleic Acids· September 2023

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Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton.
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, David G Monroe

Nat Commun· July 2023

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-- Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence.
Japneet Kaur, Dominik Saul, Madison L Doolittle, Joshua N Farr, Sundeep Khosla, David G Monroe

JBMR Plus· June 2023

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and effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L Doolittle, David G Monroe

Aging (Albany NY)· May 2023

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Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Joshua N Farr, Dominik Saul, Madison L Doolittle, Japneet Kaur, Jennifer L Rowsey, David G Monroe

J Clin Invest· April 2023

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and effects of zoledronate on senescence and senescence-associated secretory phenotype markers.
Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L Doolittle, David G Monroe

bioRxiv· February 2023

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Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton.
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, David G Monroe

bioRxiv· January 2023

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Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice.
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Brittany Eckhardt, David G Monroe

J Bone Miner Res· September 2022

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