Publications by authors named "David Mottola"

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Seralutinib for the Treatment of Pulmonary Arterial Hypertension in Adults: TORREY Open-Label Extension Study.
Olivier Sitbon, Sandeep Sahay, Pilar Escribano Subías, Ronald L Zolty, John F Kingrey, David Mottola

Adv Ther· October 2025

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Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial.
Robert P Frantz, Vallerie V McLaughlin, Sandeep Sahay, Pilar Escribano Subías, Ronald L Zolty, David Mottola

Lancet Respir Med· July 2024

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TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension.
Robert P Frantz, Raymond L Benza, Richard N Channick, Kelly Chin, Luke S Howard, David Mottola

Pulm Circ· November 2021

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Lack of a pharmacokinetic interaction between treprostinil diolamine and sildenafil in healthy adult volunteers.
S Karl Gotzkowsky, Parag Kumar, David Mottola, Kevin Laliberte

J Cardiovasc Pharmacol· May 2013

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Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist.
Brendan J Whittle, Adam M Silverstein, David M Mottola, Lucie H Clapp

Biochem Pharmacol· July 2012

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Lack of a pharmacokinetic interaction between oral treprostinil and bosentan in healthy adult volunteers.
S Karl Gotzkowsky, Jasper Dingemanse, Allen Lai, David Mottola, Kevin Laliberte

J Clin Pharmacol· July 2010

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Potent effects of aerosol compared with intravenous treprostinil on the pulmonary circulation.
Brett L Sandifer, Kenneth L Brigham, E Clinton Lawrence, David Mottola, Chris Cuppels

J Appl Physiol (1985)· December 2005

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Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase.
David M Mottola, Jason D Kilts, Mechelle M Lewis, Hilary S Connery, Q David Walker

J Pharmacol Exp Ther· June 2002

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