Publications by authors named "David Myles"

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Pancreatic cancer can be scary, hospice care isn't.
David E Myles

J Natl Med Assoc· November 2025

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Discovery of Palazestrant (OP-1250), a Potent and Orally Bioavailable Complete Estrogen Receptor Antagonist (CERAN) and Selective Estrogen Receptor Degrader (SERD).
Raymond A Ng, Susanna Barratt, Alison Parisian, Gopinath S Palanisamy, Samiron Phukan, David C Myles

ACS Omega· June 2025

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Why men don't talk about domestic violence.
David E Myles

J Natl Med Assoc· December 2024

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Grindr? it's a "Blackmailer's goldmine"! The weaponization of queer data publics Amid the US-China trade conflict.
David Myles

Sexualities· October 2024

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Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination.
Alison D Parisian, Susanna A Barratt, Leslie Hodges-Gallagher, Fabian E Ortega, Guadalupe Peña, David C Myles

Mol Cancer Ther· March 2024

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Why advocating for children and vaccine equity is not zero-sum.
David E Myles

J Natl Med Assoc· February 2022

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A Time for Everything: Why it is Time for You to Run for Office.
David E Myles

J Natl Med Assoc· April 2021

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U-BIOPRED: evaluation of the value of a public-private partnership to industry.
John H Riley, Veit J Erpenbeck, John G Matthews, Cecile T J Holweg, Christopher Compton, David Myles

Drug Discov Today· September 2018

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Selective Mechanical Transfer Deposition of Langmuir Graphene Films for High-Performance Silver Nanowire Hybrid Electrodes.
Matthew J Large, Sean P Ogilvie, Sultan Alomairy, Terence Vöckerodt, David Myles

Langmuir· October 2017

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Asthma research in Europe: a transformative agenda for innovation and competitiveness.
Nikolaos G Papadopoulos, Aggeliki Androutsopoulou, Cezmi Akdis, Sven-Erik Dahlén, Ratko Djukanovic, David Myles

Eur Respir J· May 2017

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Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.
Dominick E Shaw, Ana R Sousa, Stephen J Fowler, Louise J Fleming, Graham Roberts, David Myles

Eur Respir J· November 2015

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Characteristics of children eligible for public health insurance but uninsured: data from the 2007 National Survey of Children's Health.
Michael Crocetti, Sharon R Ghazarian, David Myles, Osondu Ogbuoji, Tina L Cheng

Matern Child Health J· April 2012

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The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series.
Yaoquan Liu, Christopher W Carreras, Mark Claypool, David C Myles, Simon J Shaw

Bioorg Med Chem Lett· June 2011

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9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety.
Yaoquan Liu, Yong Li, David C Myles, Mark Claypool, Christopher W Carreras

Bioorg Med Chem· November 2010

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9-Dihydroerythromycins as non-antibiotic motilin receptor agonists.
Yaoquan Liu, Yong Li, Yue Chen, Hao Zheng, Mark Claypool, David C Myles

Bioorg Med Chem Lett· October 2010

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Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.
Simon J Shaw, Yue Chen, Hao Zheng, Hong Fu, Mark A Burlingame, David C Myles

J Med Chem· November 2009

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Potent cytotoxic C-11 modified geldanamycin analogues.
Zong-Qiang Tian, Zhan Wang, Karen S MacMillan, Yiqing Zhou, Christopher W Carreras, David C Myles

J Med Chem· May 2009

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Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones.
Ting-Chao Chou, Xiuguo Zhang, Zi-Yang Zhong, Yong Li, Li Feng, David R Myles

Proc Natl Acad Sci U S A· September 2008

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Investigating amine derivatives of ambruticin VS-5 and VS-4.
Zong-Qiang Tian, Zhan Wang, Yuan Xu, Chau Q Tran, David C Myles

ChemMedChem· June 2008

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Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region.
Simon J Shaw, Hugo G Menzella, David C Myles, Ming Xian, Amos B Smith

Org Biomol Chem· September 2007

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Relationship among ligand conformations in solution, in the solid state, and at the Hsp90 binding site: geldanamycin and radicicol.
Pahk Thepchatri, Tomasso Eliseo, Daniel O Cicero, David Myles, James P Snyder

J Am Chem Soc· March 2007

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C-15 thiazol-4-yl analogues of (E)-9,10-didehydroepothilone D: synthesis and cytotoxicity.
Brian R Hearn, Dan Zhang, Yong Li, David C Myles

Org Lett· July 2006

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A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions.
Simon J Shaw, Kurt F Sundermann, Mark A Burlingame, Dan Zhang, Joseph Petryka, David C Myles

Bioorg Med Chem Lett· April 2006

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Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides.
Hong Fu, Saul Marquez, Xiangrong Gu, Leonard Katz, David C Myles

Bioorg Med Chem Lett· March 2006

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Methanolysis products of disorazole A1.
Brian R Hearn, Robert L Arslanian, Hong Fu, Fenghua Liu, Hugo Gramajo, David C Myles

J Nat Prod· January 2006

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