Publications by authors named "David O Arnar"

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Observational and Mendelian randomization studies of plasma sclerostin levels do not provide evidence of cardiovascular adverse effects of sclerostin inhibition.
Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Grimur Hjorleifsson Eldjarn, Hildur M Aegisdottir, Unnur Styrkarsdottir, David O Arnar

Hum Mol Genet· December 2025

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Effect of a digital health intervention on outpatients with heart failure: a randomized, controlled trial.
David O Arnar, Bartosz Dobies, Elias F Gudmundsson, Heida B Bragadottir, Gudbjorg Jona Gudlaugsdottir

Eur Heart J Digit Health· July 2025

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Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.
Carolina Roselli, Ida Surakka, Morten S Olesen, Gardar Sveinbjornsson, Nicholas A Marston, David O Arnar, John Barnard

Nat Genet· March 2025

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Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.
Seung Hoan Choi, Sean J Jurgens, Ling Xiao, Matthew C Hill, Christopher M Haggerty, David O Arnar, John Barnard

Nat Genet· March 2025

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Missense variants in FRS3 affect body mass index in populations of diverse ancestries.
Andrea B Jonsdottir, Gardar Sveinbjornsson, Rosa B Thorolfsdottir, Max Tamlander, Vinicius Tragante, David O Arnar

Nat Commun· March 2025

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Genome-Wide Association Study of Accessory Atrioventricular Pathways.
Hildur M Aegisdottir, Laura Andreasen, Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Andrea B Jonsdottir, David O Arnar

JAMA Cardiol· November 2024

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Sequence variants associated with BMI affect disease risk through BMI itself.
Gudmundur Einarsson, Gudmar Thorleifsson, Valgerdur Steinthorsdottir, Florian Zink, Hannes Helgason, Audunn S Snaebjarnarson, David O Arnar

Nat Commun· November 2024

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Variants at the Interleukin 1 Gene Locus and Pericarditis.
Rosa B Thorolfsdottir, Andrea B Jonsdottir, Gardar Sveinbjornsson, Hildur M Aegisdottir, Asmundur Oddsson, David O Arnar

JAMA Cardiol· February 2024

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Actionable Genotypes and Their Association with Life Span in Iceland.
Brynjar O Jensson, Gudny A Arnadottir, Hildigunnur Katrinardottir, Run Fridriksdottir, Hannes Helgason, David O Arnar

N Engl J Med· November 2023

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Complex effects of sequence variants on lipid levels and coronary artery disease.
Audunn S Snaebjarnarson, Anna Helgadottir, Gudny A Arnadottir, Erna V Ivarsdottir, Gudmar Thorleifsson, David O Arnar

Cell· September 2023

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Genetic insights into resting heart rate and its role in cardiovascular disease.
Yordi J van de Vegte, Ruben N Eppinga, M Yldau van der Ende, Yanick P Hagemeijer, Yuvaraj Mahendran, David O Arnar

Nat Commun· August 2023

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Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events.
Hannes Helgason, Thjodbjorg Eiriksdottir, Magnus O Ulfarsson, Abhishek Choudhary, Sigrun H Lund, David O Arnar

JAMA· August 2023

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Physical and cognitive impact following SARS-CoV-2 infection in a large population-based case-control study.
Hilma Holm, Erna V Ivarsdottir, Thorhildur Olafsdottir, Rosa Thorolfsdottir, Elias Eythorsson, David O Arnar

Commun Med (Lond)· July 2023

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Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland.
Gardar Sveinbjornsson, Bara D Benediktsdottir, Gunnlaugur Sigfusson, Kristjan Norland, Olafur B Davidsson, David O Arnar

J Am Heart Assoc· July 2023

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Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Hao Yu Chen, Christian Dina, Aeron M Small, Christian M Shaffer, Rebecca T Levinson, David O Arnar

Eur Heart J· June 2023

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Genetic variants associated with syncope implicate neural and autonomic processes.
Hildur M Aegisdottir, Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Olafur A Stefansson, Bjarni Gunnarsson, David O Arnar

Eur Heart J· March 2023

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Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles: a Mendelian randomization analysis.
Anna Helgadottir, Gudmar Thorleifsson, Audunn Snaebjarnarson, Lilja Stefansdottir, Gardar Sveinbjornsson, David O Arnar

Eur J Prev Cardiol· December 2022

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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Krishna G Aragam, Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N Wolford, David O Arnar

Nat Genet· December 2022

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Multiomics study of nonalcoholic fatty liver disease.
Gardar Sveinbjornsson, Magnus O Ulfarsson, Rosa B Thorolfsdottir, Benedikt A Jonsson, Eythor Einarsson, David O Arnar, Auðunn S Snaebjarnarson

Nat Genet· November 2022

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Improving outpatient care for heart failure through digital innovation: a feasibility study.
David O Arnar, Saemundur J Oddsson, Thrudur Gunnarsdottir, Gudbjorg Jona Gudlaugsdottir, Elias Freyr Gudmundsson

Pilot Feasibility Stud· November 2022

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Genetic Variants Close to , , and Associate With AVNRT.
Laura Andreasen, Gustav Ahlberg, Hildur M Ægisdottir, Gardar Sveinbjörnsson, Pia R Lundegaard, David O Arnar

Circ Res· October 2022

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Large-Scale Screening for Monogenic and Clinically Defined Familial Hypercholesterolemia in Iceland.
Eythór Björnsson, Guðmundur Thorgeirsson, Anna Helgadóttir, Guðmar Thorleifsson, Garðar Sveinbjörnsson, Davíð O Arnar

Arterioscler Thromb Vasc Biol· October 2021

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Distinction between the effects of parental and fetal genomes on fetal growth.
Thorhildur Juliusdottir, Valgerdur Steinthorsdottir, Lilja Stefansdottir, Gardar Sveinbjornsson, Erna V Ivarsdottir, David O Arnar

Nat Genet· August 2021

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Genetic insight into sick sinus syndrome.
Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Hildur M Aegisdottir, Stefania Benonisdottir, Lilja Stefansdottir, David O Arnar

Eur Heart J· May 2021

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Unexplained sudden death: next-generation sequencing to the rescue?
Gudny A Arnadottir, David O Arnar

Europace· March 2021

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