Publications by authors named "David O Toft"

Claim this Profile
P
Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies.
Erin Schenk, Andrea E Wahner Hendrickson, Donald Northfelt, David O Toft, Matthew M Ames

Invest New Drugs· October 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors.
Joleen Hubbard, Charles Erlichman, David O Toft, Rui Qin, Bridget A Stensgard

Invest New Drugs· June 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of plant p23-like proteins for their co-chaperone activities.
Zhongming Zhang, William Sullivan, Sara J Felts, Bishun D Prasad, David O Toft

Cell Stress Chaperones· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
Li Ni, Chun-Song Yang, Daniel Gioeli, Henry Frierson, David O Toft

Mol Cell Biol· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions.
David F Smith, David O Toft

Mol Endocrinol· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cisplatin abrogates the geldanamycin-induced heat shock response.
Andrea K McCollum, Kara B Lukasiewicz, Cynthia J Teneyck, Wilma L Lingle, David O Toft

Mol Cancer Ther· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.
Andrea K McCollum, Cynthia J TenEyck, Bridget Stensgard, Bruce W Morlan, Karla V Ballman, David O Toft

Cancer Res· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GCUNC45 is the first Hsp90 co-chaperone to show alpha/beta isoform specificity.
Ahmed Chadli, Sara J Felts, David O Toft

J Biol Chem· April 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functioning of the Hsp90 machine in chaperoning checkpoint kinase I (Chk1) and the progesterone receptor (PR).
Sara J Felts, Larry M Karnitz, David O Toft

Cell Stress Chaperones· March 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism.
Andrea K McCollum, Cynthia J Teneyck, Brian M Sauer, David O Toft, Charles Erlichman

Cancer Res· November 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer.
Grzegorz S Nowakowski, Andrea K McCollum, Matthew M Ames, Sumithra J Mandrekar, Joel M Reid, David O Toft

Clin Cancer Res· October 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.
Sonnet J H Arlander, Sara J Felts, Jill M Wagner, Bridget Stensgard, David O Toft

J Biol Chem· February 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Jeffrey J Kovacs, Patrick J M Murphy, Stéphanie Gaillard, Xuan Zhao, June-Tai Wu, David O Toft

Mol Cell· May 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70.
Amerigo Carrello, Rudi K Allan, Sarah L Morgan, Barbara A L Owen, Danny Mok, David O Toft

Cell Stress Chaperones· February 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel in situ assay for the identification and characterization of soluble nuclear mobility factors.
Cem Elbi, Dawn A Walker, Marcia Lewis, Guillermo Romero, William P Sullivan, David O Toft

Sci STKE· June 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
p23, a simple protein with complex activities.
Sara J Felts, David O Toft

Cell Stress Chaperones· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular chaperones function as steroid receptor nuclear mobility factors.
Cem Elbi, Dawn A Walker, Guillermo Romero, William P Sullivan, David O Toft

Proc Natl Acad Sci U S A· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel activation step required for transcriptional competence of progesterone receptor on chromatin templates.
Varykina G Thackray, David O Toft, Steven K Nordeen

Mol Endocrinol· December 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.
Sonnet J H Arlander, Alex K Eapen, Benjamin T Vroman, Robert J McDonald, David O Toft

J Biol Chem· December 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery.
William B Pratt, David O Toft

Exp Biol Med (Maywood)· February 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The influence of ATP and p23 on the conformation of hsp90.
William P Sullivan, Barbara A L Owen, David O Toft

J Biol Chem· November 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex.
M Patricia Hernández, William P Sullivan, David O Toft

J Biol Chem· October 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor.
M Patricia Hernández, Ahmed Chadli, David O Toft

J Biol Chem· April 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of heat shock protein 90 ATPase activity by sequences in the carboxyl terminus.
Barbara A L Owen, William P Sullivan, Sara J Felts, David O Toft

J Biol Chem· March 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of geldanamycin on androgen receptor function and stability.
Donkena Krishna Vanaja, Susan H Mitchell, David O Toft, Charles Y F Young

Cell Stress Chaperones· January 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis