Publications by authors named "David P Cook"

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Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets.
Jasmine T Plummer, Felipe Segato Dezem, David P Cook, Jiwoon Park, Luke Zhang

Nat Biotechnol· December 2025

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A Human Single-Nuclei Atlas Reveals Novel Cell States during the Pseudoglandular-to-Canalicular Transition.
Laurent Renesme, Flore Lesage, David P Cook, Adithya Achuthan, Shumei Zhong

Am J Respir Cell Mol Biol· October 2025

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Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension.
Nicholas D Cober, Emma McCourt, Rafael Soares Godoy, Yupu Deng, Ken Schlosser, David P Cook

Cardiovasc Res· October 2025

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Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.
Dalia Ibrahim, Melanie Grondin, Kristianne Galpin, Sara Asif, Emily Thompson, David P Cook

Front Immunol· August 2025

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Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.
Aristeidis Papargyriou, Mulham Najajreh, David P Cook, Carlo H Maurer, Stefanie Bärthel

Nat Biomed Eng· June 2025

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Single-Cell RNA Sequencing to Guide Autologous Preterm Cord Mesenchymal Stromal Cell Therapy.
Chanèle Cyr-Depauw, Ivana Mižik, David P Cook, Flore Lesage, Arul Vadivel

Am J Respir Crit Care Med· March 2025

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The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells.
Andrew T Plygawko, Camille Stephan-Otto Attolini, Ioanna Pitsidianaki, David P Cook, Alistair C Darby

Dev Cell· February 2025

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LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs.
Juan Zhang, Lamisa Ataei, Kirti Mittal, Liang Wu, Lauren Caldwell, David P Cook

Dev Cell· January 2025

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Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGFβ and Hippo signalling to drive regeneration.
Mardi Fink, Kizito Njah, Shyam J Patel, David P Cook, Vanessa Man

Nat Cell Biol· December 2024

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PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.
Sarah Spear, Olivia Le Saux, Hasan B Mirza, Nayana Iyer, Katie Tyson, David P Cook

Cancer Res· November 2024

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Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells.
Chanèle Cyr-Depauw, David P Cook, Ivana Mižik, Flore Lesage, Arul Vadivel

Am J Respir Crit Care Med· September 2024

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Transcriptional regulation of the postnatal cardiac conduction system heterogeneity.
Yena Oh, Rimshah Abid, Saif Dababneh, Marwan Bakr, Termeh Aslani, David P Cook

Nat Commun· August 2024

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PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway.
Jonathan J Hodgins, John Abou-Hamad, Colin Edward O'Dwyer, Ash Hagerman, Edward Yakubovich, David P Cook

J Exp Med· July 2024

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FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models.
Kristianne J C Galpin, Galaxia M Rodriguez, Vincent Maranda, David P Cook, Elizabeth Macdonald

Sci Rep· January 2024

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Mesenchymal ovarian cancer cells promote CD8 T cell exhaustion through the LGALS3-LAG3 axis.
Edward Yakubovich, David P Cook, Galaxia M Rodriguez, Barbara C Vanderhyden

NPJ Syst Biol Appl· December 2023

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Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer.
David P Cook, Kristianne J C Galpin, Galaxia M Rodriguez, Noor Shakfa, Juliette Wilson-Sanchez

Commun Biol· November 2023

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Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation.
Rafael Soares Godoy, Nicholas D Cober, David P Cook, Emma McCourt, Yupu Deng

Elife· April 2023

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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.
Allison Loan, Joseph Wai-Hin Leung, David P Cook, Chelsea Ko, Barbara C Vanderhyden

iScience· March 2023

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Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells.
Yun-Kyo Kim, Brandon Cho, David P Cook, Dan Trcka, Jeffrey L Wrana

Cell Rep· January 2023

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Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics.
Marisa Market, Gayashan Tennakoon, Marlena Scaffidi, David P Cook, Leonard Angka

Int J Mol Sci· November 2022

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Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice.
David A Landry, Edward Yakubovich, David P Cook, Sijyl Fasih, Jeremy Upham

Sci Adv· September 2022

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Single-cell transcriptomic analysis of neuroepithelial cells and other cell types of the gills of zebrafish (Danio rerio) exposed to hypoxia.
Wen Pan, Rafael Soares Godoy, David P Cook, Angela L Scott, Colin A Nurse

Sci Rep· June 2022

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The Tumor Immune Profile of Murine Ovarian Cancer Models: An Essential Tool For Ovarian Cancer Immunotherapy Research.
Galaxia M Rodriguez, Kristianne J C Galpin, David P Cook, Edward Yakubovich, Vincent Maranda

Cancer Res Commun· June 2022

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Single-Cell RNA Sequencing-Based Characterization of Resident Lung Mesenchymal Stromal Cells in Bronchopulmonary Dysplasia.
Ivana Mižíková, Flore Lesage, Chanele Cyr-Depauw, David P Cook, Maria Hurskainen

Stem Cells· May 2022

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When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer.
Mohamed S Hasim, Marie Marotel, Jonathan J Hodgins, Elisabetta Vulpis, Olivia J Makinson, David P Cook

Sci Adv· April 2022

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