Publications by authors named "David Patsch"

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Enriching productive mutational paths accelerates enzyme evolution.
David Patsch, Thomas Schwander, Moritz Voss, Daniela Schaub, Sean Hüppi

Nat Chem Biol· December 2024

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Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor.
Sumire Honda Malca, Nadine Duss, Jasmin Meierhofer, David Patsch, Michael Niklaus

Commun Chem· February 2024

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LibGENiE - A bioinformatic pipeline for the design of information-enriched enzyme libraries.
David Patsch, Michael Eichenberger, Moritz Voss, Uwe T Bornscheuer, Rebecca M Buller

Comput Struct Biotechnol J· September 2023

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Improving Enzyme Fitness with Machine Learning.
David Patsch, Rebecca Buller

Chimia (Aarau)· March 2023

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Algorithm-aided engineering of aliphatic halogenase WelO5* for the asymmetric late-stage functionalization of soraphens.
Johannes Büchler, Sumire Honda Malca, David Patsch, Moritz Voss, Nicholas J Turner

Nat Commun· January 2022

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Asymmetric Cation-Olefin Monocyclization by Engineered Squalene-Hopene Cyclases.
Michael Eichenberger, Sean Hüppi, David Patsch, Natalie Aeberli, Raphael Berweger

Angew Chem Int Ed Engl· December 2021

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Production of the Carboxylate Reductase from Nocardia otitidiscaviarum in a Soluble, Active Form for in vitro Applications.
Douglas Weber, David Patsch, Annika Neumann, Margit Winkler, Dörte Rother

Chembiochem· May 2021

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