Publications by authors named "David Qualtrough"

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Chronic Fatty Acid Exposure Disrupts SH-SY5Y and Neuronal Differentiation and Is a Potential Link Between Type-2 Diabetes and Alzheimer's Disease.
Imogen L Targett, Kate Pring, Ana I Martinez Valiente, David Qualtrough, Myra E Conway

Mol Neurobiol· November 2025

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Identifying targetable metabolic dependencies across colorectal cancer progression.
Danny N Legge, Tracey J Collard, Ewelina Stanko, Ashley J Hoskin, Amy K Holt, David Qualtrough

Mol Metab· December 2024

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Differential expression of the BCAT isoforms between breast cancer subtypes.
Mai Ahmed Shafei, Arwa Flemban, Carl Daly, Paul Kendrick, Paul White, David Qualtrough

Breast Cancer· May 2021

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BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Mai Ahmed Shafei, Thomas Forshaw, Jasmine Davis, Arwa Flemban, David Qualtrough

Oncotarget· May 2020

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Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line.
Carl S Daly, Arwa Flemban, Mai Shafei, Myra E Conway, David Qualtrough

Oncol Rep· February 2018

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The Potential Role of Hedgehog Signaling in the Luminal/Basal Phenotype of Breast Epithelia and in Breast Cancer Invasion and Metastasis.
Arwa Flemban, David Qualtrough

Cancers (Basel)· September 2015

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The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells.
David Qualtrough, Phil Rees, Beverley Speight, Ann C Williams, Christos Paraskeva

Cancers (Basel)· September 2015

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The actin-bundling protein fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair.
David Qualtrough, Katie Smallwood, David Littlejohns, Massimo Pignatelli

BMC Gastroenterol· February 2011

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Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells.
David Qualtrough, Abderrahmane Kaidi, Simon Chell, Henry N Jabbour, Ann C Williams

Int J Cancer· August 2007

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Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia.
Abderrahmane Kaidi, David Qualtrough, Ann C Williams, Christos Paraskeva

Cancer Res· July 2006

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Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence.
Simon D Chell, Ian R Witherden, Richard R Dobson, Morganaden Moorghen, Andrew A Herman, David Qualtrough

Cancer Res· March 2006

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Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment.
David Qualtrough, Andrea Buda, William Gaffield, Ann C Williams, Christos Paraskeva

Int J Cancer· July 2004

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