Publications by authors named "David R Archer"

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Characterizing pregnancy outcomes in a humanized mouse model of sickle cell disease.
Christopher Chambliss, Elizabeth Manci, Earl Fields, Jesse Bueno, Adeola Michael, David R Archer

Br J Haematol· September 2025

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Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First-in-Human Studies in Healthy Participants and Patients.
Eleanor A Lisbon, R Clark Brown, Andrew Redfern, Ken Duchin, Aline Barth, David R Archer

Clin Pharmacol Ther· September 2025

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Complement is activated in patients with acute chest syndrome caused by sickle cell disease and represents a therapeutic target.
Satheesh Chonat, Jayre A Jones, Seema R Patel, William M Briones, Michelle L Schoettler, David R Archer

Sci Transl Med· July 2025

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Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice.
Ashish Kumar Tripathi, Sadaf Dabeer, Jun Song, Tatyana Vikulina, Susanne Roser-Page, David R Archer

Cell Death Dis· December 2024

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Impact of arginine therapy on kyotorphin in children with sickle cell disease and vaso-occlusive pain.
Rawan Korman, Dunia Hatabah, Lou Ann Brown, Frank Harris, Hagar Wilkinson, David R Archer

Blood Adv· June 2024

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Accelerated atherosclerosis in beta-thalassemia.
Julian Hurtado, Hassan Sellak, Giji Joseph, Caitlin V Lewis, Crystal R Naudin, David R Archer

Am J Physiol Heart Circ Physiol· November 2023

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Intestinal barrier dysfunction in murine sickle cell disease is associated with small intestine neutrophilic inflammation, oxidative stress, and dysbiosis.
Caitlin V Lewis, Hassan Sellak, Mariem A Sawan, Giji Joseph, Trevor M Darby, David R Archer

FASEB Bioadv· May 2023

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Adhesion molecules and cerebral microvascular hemodynamic abnormalities in sickle cell disease.
Noor Mary Abi Rached, Oluwabukola T Gbotosho, David R Archer, Jayre A Jones, Morgan S Sterling

Front Neurol· December 2022

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Increasing nitric oxide bioavailability fails to improve collateral vessel formation in humanized sickle cell mice.
Caitlin V Lewis, Hassan Sellak, Laura Hansen, Giji Joseph, Julian Hurtado, David R Archer

Lab Invest· August 2022

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Whole Blood Transcriptome Analysis in Children with Sickle Cell Anemia.
Beatrice E Gee, Andrea Pearson, Iris Buchanan-Perry, Roger P Simon, David R Archer

Front Genet· January 2022

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Role of age and neuroinflammation in the mechanism of cognitive deficits in sickle cell disease.
Raven A Hardy, Noor Abi Rached, Jayre A Jones, David R Archer, Hyacinth I Hyacinth

Exp Biol Med (Maywood)· January 2021

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PPARγ increases HUWE1 to attenuate NF-κB/p65 and sickle cell disease with pulmonary hypertension.
Andrew J Jang, Sarah S Chang, Changwon Park, Choon-Myung Lee, Raymond L Benza, David R Archer

Blood Adv· January 2021

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A pilot study of the effect of atorvastatin on endothelial function and albuminuria in sickle cell disease.
Kenneth I Ataga, David Wichlan, Laila Elsherif, Vimal K Derebail, Adane F Wogu, David R Archer

Am J Hematol· November 2019

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Plasma metabolomics analysis in sickle cell disease patients with albuminuria - an exploratory study.
Laila Elsherif, Wimal Pathmasiri, Susan McRitchie, David R Archer, Kenneth I Ataga

Br J Haematol· May 2019

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Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease.
Hyacinth I Hyacinth, Courtney L Sugihara, Thomas L Spencer, David R Archer, Andy Y Shih

J Cereb Blood Flow Metab· February 2019

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Impaired Collateral Vessel Formation in Sickle Cell Disease.
Derick Okwan-Duodu, Laura Hansen, Giji Joseph, Alicia N Lyle, Daiana Weiss, David R Archer

Arterioscler Thromb Vasc Biol· May 2018

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Renal protection by atorvastatin in a murine model of sickle cell nephropathy.
Rima S Zahr, Prasanthi Chappa, Hong Yin, Lou A Brown, Kenneth I Ataga, David R Archer

Br J Haematol· April 2018

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Losartan therapy decreases albuminuria with stable glomerular filtration and permselectivity in sickle cell anemia.
Marianne E Yee, Peter A Lane, David R Archer, Clinton H Joiner, James R Eckman

Blood Cells Mol Dis· March 2018

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Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke but Respond to Tissue-Type Plasminogen Activator Treatment.
Yu-Yo Sun, Jolly Lee, Henry Huang, Mary B Wagner, Clinton H Joiner, David R Archer

Stroke· December 2017

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Estimation of glomerular filtration rate using serum cystatin C and creatinine in adults with sickle cell anemia.
Marianne E M Yee, Peter A Lane, David R Archer, Clinton H Joiner, James R Eckman

Am J Hematol· October 2017

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GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
Donna Oksenberg, Kobina Dufu, Mira P Patel, Chihyuan Chuang, Zhe Li, David R Archer

Br J Haematol· October 2016

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Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia.
Kenneth I Ataga, Vimal K Derebail, Melissa Caughey, Laila Elsherif, Jessica H Shen, David R Archer

PLoS One· September 2016

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Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice.
Samit Ghosh, Chibueze A Ihunnah, Rimi Hazra, Aisha L Walker, Jason M Hansen, David R Archer

JCI Insight· April 2016

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Body composition and grip strength are improved in transgenic sickle mice fed a high-protein diet.
Patrice L Capers, Hyacinth I Hyacinth, Shayla Cue, Prasanthi Chappa, Tatyana Vikulina, David R Archer

J Nutr Sci· June 2015

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Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy.
Robert S Nickel, Ifeyinwa Osunkwo, Aneesah Garrett, Jennifer Robertson, David R Archer

Br J Haematol· May 2015

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