Publications by authors named "David R Bundle"

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Towards Understanding the Basis of Brucella Antigen-Antibody Specificity.
Amika Sood, David R Bundle, Robert J Woods

Molecules· July 2025

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The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity.
Pankaj Sharma, Xiaolong Zhang, Kevin Ly, Yuxiang Zhang, Yu Hu, David R Bundle

Science· February 2024

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The lipid Gb3 promotes germinal center B cell responses and anti-viral immunity.
Pankaj Sharma, Xiaolong Zhang, Kevin Ly, Yuxiang Zhang, Yu Hu, David R Bundle

bioRxiv· September 2023

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The Tip of O-Polysaccharide Is a Potent Epitope in Response to Brucellosis Infection and Enables Short Synthetic Antigens to Be Superior Diagnostic Reagents.
Lucy Duncombe, Laurence Howells, Anna Haughey, Andrew V Taylor, Daryan Kaveh, David R Bundle

Microorganisms· March 2022

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A Three Component Synthetic Vaccine Containing a β-Mannan T-Cell Peptide Epitope and a β-Glucan Dendritic Cell Ligand.
David R Bundle, Eugenia Paszkiewicz, Hassan R H Elsaidi, Satadru Sekhar Mandal, Susmita Sarkar

Molecules· August 2018

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Brucellosis: Improved Diagnostics and Vaccine Insights from Synthetic Glycans.
David R Bundle, John McGiven

Acc Chem Res· December 2017

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Clustering of P-trisaccharides on amphiphilic cyclodextrin reveals unprecedented affinity for the Shiga-like toxin Stx2.
Ping Zhang, Eugenia Paszkiewicz, Qifang Wang, Joanna M Sadowska, Pavel I Kitov, David R Bundle

Chem Commun (Camb)· September 2017

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Synthetic glycoconjugates characterize the fine specificity of Brucella A and M monoclonal antibodies.
Satadru Sekhar Mandal, N Vijaya Ganesh, Joanna M Sadowska, David R Bundle

Org Biomol Chem· May 2017

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Novel Solutions for Vaccines and Diagnostics To Combat Brucellosis.
Satadru Sekhar Mandal, Lucy Duncombe, N Vijaya Ganesh, Susmita Sarkar, Laurence Howells, David R Bundle

ACS Cent Sci· March 2017

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Temporary Conversion of Protein Amino Groups to Azides: A Synthetic Strategy for Glycoconjugate Vaccines.
Tomasz Lipinski, David R Bundle

Methods Mol Biol· April 2016

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Monoclonal Antibody-Defined Specific C Epitope of Brucella O-Polysaccharide Revisited.
Michel S Zygmunt, David R Bundle, N Vijaya Ganesh, Julie Guiard, Axel Cloeckaert

Clin Vaccine Immunol· August 2015

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Synthesis of a 1,3 β-glucan hexasaccharide designed to target vaccines to the dendritic cell receptor, Dectin-1.
Hassan R H Elsaidi, Eugenia Paszkiewicz, David R Bundle

Carbohydr Res· May 2015

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Improved serodiagnosis of bovine brucellosis by novel synthetic oligosaccharide antigens representing the capping m epitope elements of Brucella O-polysaccharide.
John McGiven, Laurence Howells, Lucy Duncombe, Judy Stack, N Vijaya Ganesh, David R Bundle

J Clin Microbiol· April 2015

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Synthesis of antifungal vaccines by conjugation of β-1,2 trimannosides with T-cell peptides and covalent anchoring of neoglycopeptide to tetanus toxoid.
Jonathan Cartmell, Eugenia Paszkiewicz, Sebastian Dziadek, Pui-Hang Tam, Thanh Luu, David R Bundle

Carbohydr Res· February 2015

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Evaluation of a focused virtual library of heterobifunctional ligands for Clostridium difficile toxins.
Carlos A Sanhueza, Jonathan Cartmell, Amr El-Hawiet, Adam Szpacenko, Elena N Kitova, David R Bundle

Org Biomol Chem· January 2015

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Molecular recognition of Brucella A and M antigens dissected by synthetic oligosaccharide glycoconjugates leads to a disaccharide diagnostic for brucellosis.
N Vijaya Ganesh, Joanna M Sadowska, Susmita Sarkar, Laurence Howells, John McGiven, David R Bundle

J Am Chem Soc· November 2014

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Synthesis of high-mannose 1-thio glycans and their conjugation to protein.
Justin J Bailey, David R Bundle

Org Biomol Chem· April 2014

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Oligosaccharides and peptide displayed on an amphiphilic polymer enable solid phase assay of hapten specific antibodies.
David R Bundle, Pui-Hang Tam, Huu-Anh Tran, Eugenia Paszkiewicz, Jonathan Cartmell

Bioconjug Chem· April 2014

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Discovery of inhibitors of Shiga toxin type 2 by on-plate generation and screening of a focused compound library.
Somnath Dasgupta, Pavel I Kitov, Joanna M Sadowska, David R Bundle

Angew Chem Int Ed Engl· February 2014

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The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.
Jared M Jacobson, Jiang Yin, Pavel I Kitov, George Mulvey, Tom P Griener, David R Bundle

J Biol Chem· January 2014

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Synthesis of modified Trichinella spiralis disaccharide epitopes and a comparison of their recognition by chemical mapping and saturation transfer difference NMR.
Lina Cui, Chang-Chun Ling, Joanna Sadowska, David R Bundle

Carbohydr Res· January 2014

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Poly(N-vinyl-2-pyrrolidone-co-vinyl alcohol), a versatile amphiphilic polymeric scaffold for multivalent probes.
Pavel I Kitov, Yohei Kotsuchibashi, Eugenia Paszkiewicz, Dennis Wilhelm, Ravin Narain, David R Bundle

Org Lett· October 2013

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Synthesis of a trisaccharide repeat of the zwitterionic Sp1 capsular polysaccharide utilizing 2-Azido-4-benzylamino-4N,3-O-carbonyl-2,4,6-trideoxy-d-galactopyranosyl trichloroacetimidate.
Ithayavani Iynkkaran, David R Bundle

Carbohydr Res· August 2013

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The synthesis of a multivalent heterobifunctional ligand for specific interaction with Shiga toxin 2 produced by E. coli O157:H7.
Jared M Jacobson, Pavel I Kitov, David R Bundle

Carbohydr Res· August 2013

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Design and synthesis of a universal antigen to detect brucellosis.
Julie Guiard, Eugenia Paszkiewicz, Joanna Sadowska, David R Bundle

Angew Chem Int Ed Engl· July 2013

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