Publications by authors named "David R Edwards"

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C
Correction to "Catalysis by a De Novo Zinc-Mediated Protein Interface: Implications for Natural Enzyme Evolution and Rational Enzyme Engineering".
Bryan S Der, David R Edwards, Brian Kuhlman

Biochemistry· October 2023

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Lower limb orthopaedic surgery results in changes to coagulation and non-specific inflammatory biomarkers, including selective clinical outcome measures.
Stephen F Hughes, Beverly D Hendricks, David R Edwards, Salah S Bastawrous, Jim F Middleton

Eur J Med Res· November 2013

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Catalysis by desolvation: the catalytic prowess of SAM-dependent halide-alkylating enzymes.
Danielle C Lohman, David R Edwards, Richard Wolfenden

J Am Chem Soc· October 2013

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Development of metal-ion containing catalysts for the decomposition of phosphorothioate esters.
David R Edwards, R Stan Brown

Biochim Biophys Acta· January 2013

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Proton-in-flight mechanism for the spontaneous hydrolysis of N-methyl O-phenyl sulfamate: implications for the design of steroid sulfatase inhibitors.
David R Edwards, Richard Wolfenden

J Org Chem· May 2012

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Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering.
Bryan S Der, David R Edwards, Brian Kuhlman

Biochemistry· May 2012

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Hydrolysis of N-alkyl sulfamates and the catalytic efficiency of an S-N cleaving sulfamidase.
Danielle C Lohman, Richard Wolfenden, David R Edwards

J Org Chem· March 2012

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Catalytic proficiency: the extreme case of S-O cleaving sulfatases.
David R Edwards, Danielle C Lohman, Richard Wolfenden

J Am Chem Soc· January 2012

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A study of the kinetics of La3+-promoted methanolysis of S-aryl methylphosphonothioates: possible methodology for decontamination of EA 2192, the toxic byproduct of VX hydrolysis.
Basab B Dhar, David R Edwards, R Stan Brown

Inorg Chem· April 2011

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Study on the transesterification of methyl aryl phosphorothioates in methanol promoted by Cd(II), Mn(II), and a synthetic Pd(II) complex.
David R Edwards, Alexei A Neverov, R Stan Brown

Inorg Chem· March 2011

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Mechanistic and computational study of a palladacycle-catalyzed decomposition of a series of neutral phosphorothioate triesters in methanol.
C Tony Liu, Christopher I Maxwell, David R Edwards, Alexei A Neverov, Nicholas J Mosey

J Am Chem Soc· November 2010

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Tourniquet-applied upper limb orthopaedic surgery results in increased inflammation and changes to leukocyte, coagulation and endothelial markers.
Stephen F Hughes, Beverly D Hendricks, David R Edwards, Jim F Middleton

PLoS One· July 2010

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On the question of stepwise vs. concerted cleavage of RNA models promoted by a synthetic dinuclear Zn(II) complex in methanol: implementation of a noncleavable phosphonate probe.
David R Edwards, Wing-Yin Tsang, Alexei A Neverov, R Stan Brown

Org Biomol Chem· February 2010

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Total hip and knee replacement surgery results in changes in leukocyte and endothelial markers.
Stephen F Hughes, Beverly D Hendricks, David R Edwards, Kirsty M Maclean, Salah S Bastawrous

J Inflamm (Lond)· January 2010

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Leaving group assistance in the La3+-catalyzed cleavage of dimethyl (o-methoxycarbonyl)aryl phosphate triesters in methanol.
David R Edwards, C Tony Liu, Graham E Garrett, Alexei A Neverov, R Stan Brown

J Am Chem Soc· September 2009

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Dinuclear Zn(II) complex promotes cleavage and isomerization of 2-hydroxypropyl alkyl phosphates by a common cyclic phosphate intermediate.
Wing Yin Tsang, David R Edwards, Stephanie A Melnychuk, C Tony Liu, Chaomin Liu

J Am Chem Soc· March 2009

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Dissociative solvolytic cleavage of methyl (ortho-carboxymethyl)aryl phosphate diesters mediated by Yb3+ in methanol gives a 10(12)-fold rate acceleration attributable to leaving group assistance.
David R Edwards, Alexei A Neverov, R Stan Brown

J Am Chem Soc· January 2009

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Toward selective functionalisation of oligosilanes: borane-catalysed dehydrogenative coupling of silanes with thiols.
Daniel J Harrison, David R Edwards, Robert McDonald, Lisa Rosenberg

Dalton Trans· July 2008

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Regioselectivity of the rhodium-catalyzed hydroboration of vinyl arenes: electronic twists and mechanistic shifts.
David R Edwards, Yonek B Hleba, Christopher J Lata, Larry A Calhoun, Cathleen M Crudden

Angew Chem Int Ed Engl· December 2007

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Experimental investigation into the mechanism of the epoxidation of aldehydes with sulfur ylides.
David R Edwards, Pedro Montoya-Peleaz, Cathleen M Crudden

Org Lett· December 2007

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Experimental demonstration of base-catalyzed interconversion of isomeric betaine intermediates in the Corey-Chaykovsky epoxidation.
David R Edwards, Jenny Du, Cathleen M Crudden

Org Lett· June 2007

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Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers.
Stephen F Hughes, Beverly D Hendricks, David R Edwards, Salah S Bastawrous, Gareth E Roberts

J Inflamm (Lond)· May 2007

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