Publications by authors named "David R Piper"

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Controls the Maturation of Dendrites, Synaptic Function, and Network Activity in Developing Human Neurons.
Nerea Llamosas, Vineet Arora, Ridhima Vij, Murat Kilinc, Lukasz Bijoch, David R Piper

J Neurosci· October 2020

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A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons.
BanuPriya Sridharan, Christopher Hubbs, Nerea Llamosas, Murat Kilinc, Fakhar U Singhera, David R Piper

Sci Rep· June 2019

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Evaluation of Protein Kinase Inhibitors with PLK4 Cross-Over Potential in a Pre-Clinical Model of Cancer.
Amreena Suri, Anders W Bailey, Maurício T Tavares, Hendra Gunosewoyo, Connor P Dyer, David R Piper

Int J Mol Sci· April 2019

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Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma.
Simone Treiger Sredni, Anders W Bailey, Amreena Suri, Rintaro Hashizume, Xingyao He, David R Piper

Oncotarget· December 2017

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A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain.
Simone Treiger Sredni, Mario Suzuki, Jian-Ping Yang, Jacek Topczewski, Anders W Bailey, David R Piper

Pediatr Blood Cancer· November 2017

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Role of phosphoinositide 3-OH kinase p110β in skeletal myogenesis.
Ronald W Matheny, Melissa A Riddle-Kottke, Luis A Leandry, Christine M Lynch, Mary N Abdalla, David R Piper

Mol Cell Biol· April 2015

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Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach.
David R Piper, Steve R Duff, Hildegard C Eliason, W Jack Frazee, Elizabeth A Frey

Assay Drug Dev Technol· April 2008

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Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels.
David R Piper, Jason Rupp, Frank B Sachse, Michael C Sanguinetti, Martin Tristani-Firouzi

Cell Physiol Biochem· March 2008

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The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.
Tania Ferrer, Jason Rupp, David R Piper, Martin Tristani-Firouzi

J Biol Chem· May 2006

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De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero.
Kui Hong, David R Piper, Aurora Diaz-Valdecantos, Josep Brugada, Antonio Oliva

Cardiovasc Res· December 2005

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Voltage sensor movement in the hERG K+ channel.
David R Piper, Michael C Sanguinetti, Martin Tristani-Firouzi

Novartis Found Symp· August 2005

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Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating.
David R Piper, William A Hinz, Chandra K Tallurri, Michael C Sanguinetti, Martin Tristani-Firouzi

J Biol Chem· February 2005

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Gating currents associated with intramembrane charge displacement in HERG potassium channels.
David R Piper, Anthony Varghese, Michael C Sanguinetti, Martin Tristani-Firouzi

Proc Natl Acad Sci U S A· September 2003

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Voltage sensing and activation gating of HCN pacemaker channels.
Jun Chen, David R Piper, Michael C Sanguinetti

Trends Cardiovasc Med· January 2002

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