Publications by authors named "David Reif"

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Systematic evaluation of Tox21 compounds that target β-adrenergic receptors and their role in cardiotoxicity.
Xi Luo, Li Zhang, Srilatha Sakamuru, Precious A Adesina, Jinghua Zhao, David M Reif

Toxicol Appl Pharmacol· September 2025

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Updated Guidance for Communicating PFAS Identification Confidence with Ion Mobility Spectrometry.
Anna K Boatman, Jessie R Chappel, Kaylie I Kirkwood-Donelson, Jonathon F Fleming, David M Reif

Environ Sci Technol· August 2025

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Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation.
Deborah K Ngan, Srilatha Sakamuru, Jinghua Zhao, Menghang Xia, Stephen S Ferguson, David M Reif

Toxicol Appl Pharmacol· June 2025

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Expanded Tox21 biological assay panel for the prediction of drug-induced liver injury and cardiotoxicity.
Tuan Xu, Masato Ooka, Jinghua Zhao, Srilatha Sakamuru, Deborah K Ngan, David M Reif

Environ Health Perspect· June 2025

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Updated Guidance for Communicating PFAS Identification Confidence with Ion Mobility Spectrometry.
Anna K Boatman, Jessie R Chappel, Kaylie I Kirkwood-Donelson, Jonathon F Fleming, David M Reif

bioRxiv· May 2025

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Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes.
Srilatha Sakamuru, Jameson Travers, Carleen Klumpp-Thomas, Ruili Huang, Kristine L Witt, David M Reif

Int J Mol Sci· May 2025

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A review of geospatial exposure models and approaches for health data integration.
Lara P Clark, Daniel Zilber, Charles Schmitt, David C Fargo, David M Reif, Alison A Motsinger-Reif

J Expo Sci Environ Epidemiol· April 2025

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TAME 2.0: expanding and improving online data science training for environmental health research.
Alexis Payton, Elise Hickman, Jessie Chappel, Kyle Roell, Lauren E Koval, David M Reif

Front Toxicol· February 2025

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An in vitro and machine learning framework for quantifying serum albumin binding of per- and polyfluoroalkyl substances.
Hannah M Starnes, Adrian J Green, David M Reif, Scott M Belcher

Toxicol Sci· January 2025

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The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk.
Kyle P Messier, David M Reif, Skylar W Marvel

Hum Genomics· January 2025

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The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk.
Kyle P Messier, David M Reif, Skylar W Marvel

medRxiv· November 2024

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Streamlining Phenotype Classification and Highlighting Feature Candidates: A Screening Method for Non-Targeted Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) Data.
Jessie R Chappel, Kaylie I Kirkwood-Donelson, James N Dodds, Jonathon Fleming, David M Reif

Anal Chem· October 2024

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Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies.
Adrian J Green, Lisa Truong, Preethi Thunga, Connor Leong, Melody Hancock, David M Reif

PLoS Comput Biol· September 2024

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Use of Tox21 screening data to profile PFAS bioactivities on nuclear receptors, cellular stress pathways, and cytochrome p450 enzymes.
Masato Ooka, Srilatha Sakamuru, Jinghua Zhao, Yanyan Qu, Yuhong Fang, David Reif

J Hazard Mater· July 2024

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Gene-environment interactions within a precision environmental health framework.
Alison A Motsinger-Reif, David M Reif, Farida S Akhtari, John S House, C Ryan Campbell

Cell Genom· July 2024

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From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome.
Jessie R Chappel, Kaylie I Kirkwood-Donelson, David M Reif, Erin S Baker

Anal Bioanal Chem· April 2024

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Investigating mouse hepatic lipidome dysregulation following exposure to emerging per- and polyfluoroalkyl substances (PFAS).
Kaylie I Kirkwood-Donelson, Jessie Chappel, Emma Tobin, James N Dodds, David M Reif

Chemosphere· April 2024

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Guided optimization of ToxPi model weights using a Semi-Automated approach.
Jonathon F Fleming, John S House, Jessie R Chappel, Alison A Motsinger-Reif, David M Reif

Comput Toxicol· March 2024

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The relationship between greenspace exposure and telomere length in the National Health and Nutrition Examination Survey.
S Scott Ogletree, Jing-Huei Huang, David Reif, Lin Yang, Christopher Dunstan

Sci Total Environ· December 2023

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Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis.
William P Marinello, Sagi Enicole A Gillera, Lynn Huang, John Rollman, David M Reif

Neurotoxicology· December 2023

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Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community.
Dylan J Wallis, Nadine Kotlarz, Detlef R U Knappe, David N Collier, C Suzanne Lea, David Reif

Environ Sci Technol· October 2023

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Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies.
Adrian J Green, Lisa Truong, Preethi Thunga, Connor Leong, Melody Hancock, David M Reif

bioRxiv· September 2023

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Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics.
Jessie R Chappel, Mary E King, Jonathon Fleming, Livia S Eberlin, David M Reif

Anal Chem· August 2023

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Utilizing Aggregated Molecular Phenotype (AMP) Scores to Visualize Simultaneous Molecular Changes in Mass Spectrometry Imaging Data.
Jessie R Chappel, Mary E King, Jonathon Fleming, Livia S Eberlin, David M Reif

bioRxiv· June 2023

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Pharmacogenomic Analyses Implicate B Cell Developmental Status and as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy.
George W Small, Farida S Akhtari, Adrian J Green, Tammy M Havener, Michael Sikes, David M Reif, Alison A Motsinger-Reif

Cells· June 2023

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