Publications by authors named "David Rowitch"

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Cost-comparison of resequencing versus archival data methods for periodic reanalysis of genomic data in rare diseases diagnosis: A UK pilot analysis.
Ravi Prabhakar More, Dulika Sumathipala, Helen Dolling, Kate Downes, Sarah Bowdin, David H Rowitch

Eur J Med Genet· December 2025

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Fathers' and Mothers' support needs and support experiences after rapid genome sequencing.
Helen Dolling, Sophie Rowitch, Malachy Bromham, Stephanie Archer, Sara O'Curry, David H Rowitch

Eur J Hum Genet· December 2025

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Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism.
Adrien M Vaquié, Davod R Shah, Eliane E S Brechbühl, Michael McNicholas, Zhaoyang Xu, David H Rowitch

Mol Oncol· September 2025

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An expanded subventricular zone supports postnatal cortical interneuron migration in gyrencephalic brains.
JaeYeon Kim, Aunoy Poddar, Kadellyn Sandoval, Julia Chu, Emma Horton, David H Rowitch

Nat Neurosci· August 2025

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Genetic investigations in cerebral palsy.
Anna P Basu, Karen Low, Thiloka Ratnaike, David Rowitch

Dev Med Child Neurol· February 2025

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Oligodendrocyte Slc48a1 (Hrg1) encodes a functional heme transporter required for myelin integrity.
John H Stockley, Adrien M Vaquie, Zhaoyang Xu, Theresa Bartels, Gregory D Jordan, David H Rowitch

Glia· February 2025

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Exome and Genome Sequencing to Diagnose the Genetic Basis of Neonatal Hypotonia: An International Consortium Study.
Sarah U Morton, Gregory Costain, Courtney E French, Emma Wakeling, Anna Szuto, David Rowitch

Neurology· January 2025

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Significant oligodendrocyte progenitor and microglial cell death is a feature of remyelination following toxin-induced experimental demyelination.
Hallie Gaitsch, Peggy Assinck, Penelope Dimas, Chao Zhao, Laura Morcom, David H Rowitch

Brain Commun· January 2025

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Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Robert M Bachoo, Elizabeth A Maher, Keith L Ligon, Norman E Sharpless, Suzanne S Chan, David H Rowitch

Cancer Cell· December 2024

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Generation of Mammalian Astrocyte Functional Heterogeneity.
Theresa Bartels, David H Rowitch, Omer Ali Bayraktar

Cold Spring Harb Perspect Biol· November 2024

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Identifying barriers and opportunities to facilitate the uptake of whole genome sequencing in paediatric haematology and oncology practice.
Michelle Bishop, Aditi Vedi, Sarah Bowdin, Ruth Armstrong, Jack Bartram, David H Rowitch

BMC Med Educ· November 2024

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Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine.
Rose Ana Summers, Francesca Fagiani, David H Rowitch, Martina Absinta, Daniel S Reich

Trends Immunol· October 2024

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Editor's Note: Inhibition of Phosphatidylinositol 3-Kinase Destabilizes Mycn Protein and Blocks Malignant Progression in Neuroblastoma.
Louis Chesler, Chris Schlieve, David D Goldenberg, Anna Kenney, Grace Kim, David Rowitch

Cancer Res· October 2024

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Neuroinflammatory reactive astrocyte formation correlates with adverse outcomes in perinatal white matter injury.
Patricia Renz, Marel Steinfort, Valérie Haesler, Vera Tscherrig, Eric J Huang, David H Rowitch

Glia· September 2024

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Developmental origin of oligodendrocytes determines their function in the adult brain.
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, David H Rowitch

Nat Neurosci· August 2024

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A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression.
Tanay Ghosh, Rafael G Almeida, Chao Zhao, Abdelkrim Mannioui, Elodie Martin, David H Rowitch

Cell· February 2024

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Time-resolved single-cell RNAseq profiling identifies a novel subpopulation of inflammatory myeloid cells with delayed cytotoxic profile in chronic spinal cord injury.
Regan Hamel, Luca Peruzzotti-Jametti, Katherine Ridley, Veronica Testa, Bryan Yu, David Rowitch

Heliyon· August 2023

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Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
Hannah Kapell, Luca Fazio, Julia Dyckow, Sophia Schwarz, Andrés Cruz-Herranz, David H Rowitch

J Clin Invest· April 2023

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Clinical and Neurophysiologic Phenotypes in Neonates With Encephalopathy.
Evelina Carapancea, Marie-Coralie Cornet, Mathieu Milh, Lucrezia De Cosmo, Eric J Huang, David H Rowitch

Neurology· March 2023

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Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells.
Harry Bulstrode, Gemma C Girdler, Tannia Gracia, Alexander Aivazidis, Ilias Moutsopoulos, David H Rowitch

Neuron· December 2022

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Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion.
Koji Tanabe, Hiroko Nobuta, Nan Yang, Cheen Euong Ang, Philip Huie, David H Rowitch

Development· October 2022

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Genetic correlates of phenotypic heterogeneity in autism.
Varun Warrier, Xinhe Zhang, Patrick Reed, Alexandra Havdahl, Tyler M Moore, David H Rowitch

Nat Genet· September 2022

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Refinements and considerations for trio whole-genome sequence analysis when investigating Mendelian diseases presenting in early childhood.
Courtney E French, Helen Dolling, Karyn Mégy, Alba Sanchis-Juan, Ajay Kumar, David H Rowitch

HGG Adv· July 2022

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Multicenter Consensus Approach to Evaluation of Neonatal Hypotonia in the Genomic Era: A Review.
Sarah U Morton, John Christodoulou, Gregory Costain, Francesco Muntoni, Emma Wakeling, David H Rowitch

JAMA Neurol· April 2022

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Optimising the health-care experiences of babies, children, and young people.
Tamsin Ford, Kwabena Kusi-Mensah, Tamsin Newlove-Delgado, Paul Ramchandani, Fiona Price-Kuehne, David Rowitch

Lancet· October 2021

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