Publications by authors named "David S Libich"

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Molecular basis of EWS interdomain self-association and its role in condensate formation.
Erich J Sohn, Kandarp A Sojitra, Leticia Rodrigues, Xiaoping Xu, Bess Frost, David S Libich

Protein Sci· October 2025

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The Spliceosomal Peptidyl Prolyl Isomerase Like 1 Interacts with the Low-Complexity Domain of the RNA Binding Protein EWS Modulating Its Phase Separation Behavior.
George L Parra, Erich J Sohn, Xiaoping Xu, David S Libich

Biochemistry· August 2025

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Correction: Pandey et al. Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis. 2023, , 667.
Samjhana Pandey, Krishna K Raut, Antoine Baudin, Lamya Djemri, David S Libich

Biomolecules· August 2025

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RAD52 and RPA act in a concert promoting inverse RNA strand exchange.
Sarah F DiDomenico, Hoang H Dinh, Matthew J Rossi, Antoine Baudin, Simranjeet S Sekhon, David S Libich

bioRxiv· July 2025

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The H, N and C backbone resonance assignments of the N-terminal (1-149) domain of Serpine mRNA Binding Protein 1 (SERBP1).
Antoine Baudin, Hoang H Dinh, Xiaoping Xu, David S Libich

Biomol NMR Assign· June 2025

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Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation.
Francisco E Neal, Wenjing Li, Mollie E Uhrig, Jeffrey N Katz, Shahrez Syed, David S Libich

Cell Rep· May 2025

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Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain.
Emily E Selig, Erich J Sohn, Aiola Stoja, Alma K Moreno-Romero, Shivani Akula, David S Libich

Proc Natl Acad Sci U S A· May 2025

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CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade.
Cody M Rogers, Hardeep Kaur, Michelle L Swift, Vivek B Raina, Shuo Zhou, David S Libich

Science· May 2025

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Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma.
Erich J Sohn, David S Libich

Mol Oncol· April 2025

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SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis.
Kira Breunig, Xuifen Lei, Mauro Montalbano, Gabriela D A Guardia, Shiva Ostadrahimi, David S Libich

Elife· February 2025

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SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis.
Kira Breunig, Xiufen Lei, Mauro Montalbano, Gabriela D A Guardia, Shiva Ostadrahimi, David S Libich

bioRxiv· October 2024

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Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination.
Sameer Salunkhe, James M Daley, Hardeep Kaur, Nozomi Tomimatsu, Chaoyou Xue, David S Libich

Nature· October 2024

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Squishy to crusty: Biophysics reveal the molecular details of FUS droplet maturation.
Erich J Sohn, David S Libich

Structure· July 2024

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Insights into Molecular Diversity within the FUS/EWS/TAF15 Protein Family: Unraveling Phase Separation of the N-Terminal Low-Complexity Domain from RNA-Binding Protein EWS.
Courtney N Johnson, Kandarp A Sojitra, Erich J Sohn, Alma K Moreno-Romero, Antoine Baudin, David S Libich

J Am Chem Soc· March 2024

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Insights into Molecular Diversity within the FET Family: Unraveling Phase Separation of the N-Terminal Low Complexity Domain from RNA-Binding Protein EWS.
Courtney N Johnson, Kandarp A Sojitra, Erich J Sohn, Alma K Moreno-Romero, Antoine Baudin, David S Libich

bioRxiv· November 2023

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Defining function of wild-type and three patient-specific mutations in a zebrafish model of embryonal rhabdomyosarcoma.
Jiangfei Chen, Kunal Baxi, Amanda E Lipsitt, Nicole Rae Hensch, Long Wang, David S Libich

Elife· June 2023

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Biochemical and biophysical characterization of the nucleic acid binding properties of the RNA/DNA binding protein EWS.
Emily E Selig, Roohi Bhura, Matthew R White, Shivani Akula, Renee D Hoffman, David S Libich

Biopolymers· May 2023

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Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis.
Samjhana Pandey, Krishna K Raut, Andrea M Clark, Antoine Baudin, Lamya Djemri, David S Libich

Biomolecules· April 2023

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Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation.
David S Libich, Antoine Baudin

Structure· February 2023

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The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1.
Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Biomol NMR Assign· April 2022

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The H, N and C resonance assignments of the C-terminal domain of Serpine mRNA binding protein 1 (SERBP1).
Antoine Baudin, Xiaoping Xu, David S Libich

Biomol NMR Assign· October 2021

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Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes.
Antoine Baudin, Alma K Moreno-Romero, Xiaoping Xu, Emily E Selig, Luiz O F Penalva, David S Libich

Front Mol Biosci· September 2021

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Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins.
Courtney N Johnson, David S Libich

J Vis Exp· September 2021

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Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR.
Samuel A Kotler, Vitali Tugarinov, Thomas Schmidt, Alberto Ceccon, David S Libich

Proc Natl Acad Sci U S A· February 2019

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Extensive Sampling of the Cavity of the GroEL Nanomachine by Protein Substrates Probed by Paramagnetic Relaxation Enhancement.
Marielle A Wälti, David S Libich, G Marius Clore

J Phys Chem Lett· June 2018

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