Publications by authors named "David Sept"

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Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation.
Takashi Hotta, Morgan L Pimm, Ezekiel C Thomas, Yang Yue, Patrick DeLear, David Sept

bioRxiv· September 2025

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Conformational flexibility of tubulin dimers regulates the transitions of microtubule dynamic instability.
Maddy Shred, Nicholas E Vangos, Andrew N Bayne, Sofía Cruz Tetlalmatzi, Wang Peng, David Sept

bioRxiv· July 2025

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Motor clustering enhances kinesin-driven vesicle transport.
Rui Jiang, Qingzhou Feng, Daguan Nong, You Jung Kang, David Sept

Biophys J· June 2025

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Membrane-associated polymerases deliver most of the actin subunits to a lamellipodial network.
Kristen Skruber, David Sept, R Dyche Mullins

bioRxiv· March 2025

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Motor Clustering Enhances Kinesin-driven Vesicle Transport.
Rui Jiang, Qingzhou Feng, Daguan Nong, You Jung Kang, David Sept

bioRxiv· October 2024

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Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Vipin Rawat, Patrick DeLear, Prarthana Prashanth, Mete Emir Ozgurses, Anteneh Tebeje, David Sept

JCI Insight· May 2024

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Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein.
Olivia L Mooren, Melissa D Stuchell-Brereton, Patrick McConnell, Chenbo Yan, Emily M Wilkerson, David Sept

J Mol Biol· December 2023

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Clinical, genetic, and structural characterization of a novel TUBB4B tubulinopathy.
Jason R McFadden, Christina Deanne P Tolete, Yan Huang, Ellen Macnamara, David Sept

Mol Genet Metab Rep· September 2023

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Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein.
Olivia L Mooren, Melissa D Stuchell-Brereton, Patrick McConnell, Chenbo Yan, Emily M Wilkerson, David Sept

bioRxiv· August 2023

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Phase intensity nanoscope (PINE) opens long-time investigation windows of living matter.
Guangjie Cui, Yunbo Liu, Di Zu, Xintao Zhao, Zhijia Zhang, David Sept

Nat Commun· July 2023

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Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Vipin Rawat, Patrick DeLear, Prarthana Prashanth, Mete Emir Ozgurses, Anteneh Tebeje, David Sept

bioRxiv· July 2023

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EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules.
Takashi Hotta, Thomas S McAlear, Yang Yue, Takumi Higaki, Sarah E Haynes, David Sept

Curr Biol· September 2022

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Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.
April L Solon, Zhenyu Tan, Katherine L Schutt, Lauren Jepsen, Sarah E Haynes, David Sept

Sci Adv· November 2021

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Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms.
Breane G Budaitis, Shashank Jariwala, Lu Rao, Yang Yue, David Sept

J Cell Biol· April 2021

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Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin.
Takashi Hotta, Sarah E Haynes, Teresa L Blasius, Margo Gebbie, Emily L Eberhardt, David Sept

Curr Biol· February 2021

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Effects of Nucleotide and End-Dependent Actin Conformations on Polymerization.
Lauren Jepsen, David Sept

Biophys J· November 2020

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Entropic effects enable life at extreme temperatures.
Young Hun Kim, Geoffray Leriche, Karthik Diraviyam, Takaoki Koyanagi, Kaifu Gao, David Sept

Sci Adv· May 2019

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Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity.
Breane G Budaitis, Shashank Jariwala, Dana N Reinemann, Kristin I Schimert, Guido Scarabelli, David Sept

Elife· May 2019

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The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth.
Sami Chaaban, Shashank Jariwala, Chieh-Ting Hsu, Stefanie Redemann, Justin M Kollman, David Sept

Dev Cell· October 2018

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Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division.
Cuie Chen, Ryan Cummings, Aghapi Mordovanakis, Alan J Hunt, Michael Mayer, David Sept

Elife· March 2018

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Frequency-Based Analysis of Gramicidin A Nanopores Enabling Detection of Small Molecules with Picomolar Sensitivity.
Young Hun Kim, Leibniz Hang, Jessica L Cifelli, David Sept, Michael Mayer

Anal Chem· February 2018

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An electric-eel-inspired soft power source from stacked hydrogels.
Thomas B H Schroeder, Anirvan Guha, Aaron Lamoureux, Gloria VanRenterghem, David Sept

Nature· December 2017

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14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote .
Jana Krtková, Jennifer Xu, Marco Lalle, Melissa Steele-Ogus, Germain C M Alas, David Sept

mSphere· September 2017

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Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine.
Brian T Castle, Seth McCubbin, Louis S Prahl, Jordan N Bernens, David Sept

Mol Biol Cell· May 2017

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Hybrid Lipids Inspired by Extremophiles and Eukaryotes Afford Serum-Stable Membranes with Low Leakage.
Takaoki Koyanagi, Kevin J Cao, Geoffray Leriche, David Onofrei, Gregory P Holland, David Sept

Chemistry· May 2017

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