Publications by authors named "David Stegner"

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circFUT8 promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes.
Huang Wu, Yao Lu, Denglian Sun, Zeqing Miao, Siyuan Chen, David Stegner

Blood· October 2025

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Platelets in the regulation of glucose and lipid metabolism-functions beyond the maintenance of vascular integrity are being revealed.
Katarzyna Kolczyńska-Matysiak, Toufic Kassouf, David Stegner, Grzegorz Sumara

FEBS J· October 2025

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Casein kinase 1α essentially regulates thrombopoiesis by driving megakaryocyte maturation and cytoskeleton organization.
Ferdinand Kollotzek, Kristina Mott, Melina Fischer, Betül Findik, Vanessa Göb, David Stegner

Blood· October 2025

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Platelets drive macrophage inflammatory activation in vitro.
Anna Rizakou, Annabelle Rosa, Lukas Johannes Weiss, Ecem T Sakalli, Giuseppe Rizzo, David Stegner

J Leukoc Biol· August 2025

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EMA601 and glenzocimab: two glycoprotein VI inhibitory Fabs with different potency.
Bernhard Nieswandt, David Stegner, Stefano Navarro

Eur Heart J· July 2025

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Platelet-Derived PDGF-A Disrupts Blood-Brain Barrier Integrity in Ischemic Stroke-Brief Report.
Vanessa Göb, Lena Zimmermann, Katherina Hemmen, Axel Haarmann, Katrin G Heinze, David Stegner

Arterioscler Thromb Vasc Biol· July 2025

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Neutrophil recruitment depends on platelet-derived leukotriene B4.
Christian Hackenbroch, Tugce Cimen, Carina Gross, Stefanie Rubenzucker, Philipp Burkard, David Stegner

Blood Adv· May 2025

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The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice.
Stefano Navarro, Ivan Talucci, Vanessa Göb, Stefanie Hartmann, Sarah Beck, David Stegner

Eur Heart J· November 2024

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Dense but not alpha granules of platelets are required for insulin secretion from pancreatic β cells.
Katarzyna Kolczyńska-Matysiak, Till Karwen, Mona Loeffler, Izabela Hawro, Toufic Kassouf, David Stegner

Biochem Biophys Res Commun· November 2024

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One immune cell to bind them all: platelet contribution to neurodegenerative disease.
Gabriela Rodriguez Moore, Isabel Melo-Escobar, David Stegner, Oliver Bracko

Mol Neurodegener· September 2024

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Soluble Glycoprotein VI Levels Assessed Locally within the Extra- and Intracerebral Circulation in Hyper-Acute Thromboembolic Stroke: A Pilot Study.
Andreas Starke, Alexander M Kollikowski, Vivian Vogt, Guido Stoll, Bernhard Nieswandt, David Stegner

Biomedicines· September 2024

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Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, David Stegner

Blood· April 2024

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The bone marrow is the primary site of thrombopoiesis.
Nathan L Asquith, Estelle Carminita, Virginia Camacho, Antonio Rodriguez-Romera, David Stegner

Blood· January 2024

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Immunothrombosis versus thrombo-inflammation: platelets in cerebrovascular complications.
Lexiao Li, David Stegner

Res Pract Thromb Haemost· January 2024

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Mutations of the dimerization site of glycoprotein (GP) VI result in abolished expression.
Stefano Navarro, Timo Vögtle, Nina Groß, Julia Preu, Maximilian Englert, David Stegner

Thromb Res· December 2023

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Author Correction: Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation.
Bianca de Jonckheere, Ferdinand Kollotzek, Patrick Münzer, Vanessa Göb, Melina Fischer, David Stegner

Nat Cardiovasc Res· December 2023

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Platelet-derived lipids promote insulin secretion of pancreatic β cells.
Till Karwen, Katarzyna Kolczynska-Matysiak, Carina Gross, Mona C Löffler, Mike Friedrich, David Stegner

EMBO Mol Med· September 2023

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Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation.
Bianca de Jonckheere, Ferdinand Kollotzek, Patrick Münzer, Vanessa Göb, Melina Fischer, David Stegner

Nat Cardiovasc Res· September 2023

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Illustrated State-of-the-Art Capsules of the ISTH 2023 Congress.
Susan R Kahn, Donald M Arnold, Caterina Casari, Karl C Desch, Katrien M J Devreese, David Stegner

Res Pract Thromb Haemost· May 2023

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Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Joanne C Clark, Eleyna M Martin, Luis A Morán, Ying Di, Xueqing Wang, David Stegner

Commun Biol· April 2023

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Platelet glycoprotein V spatio-temporally controls fibrin formation.
Sarah Beck, Patricia Öftering, Renhao Li, Katherina Hemmen, Magdolna Nagy, David Stegner

Nat Cardiovasc Res· April 2023

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COVID-19 mRNA vaccine-associated cerebral venous thrombosis: Rare adverse event or coincidence?
Bingwen Eugene Fan, Ryan Ruiyang Ling, Kollengode Ramanathan, Bernard Pui Lam Leung, Xin Rong Lim, David Stegner

Am J Hematol· January 2023

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Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Tobias Petzold, Zhe Zhang, Iván Ballesteros, Inas Saleh, Amin Polzin, David Stegner

Immunity· December 2022

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The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.
Lukas J Weiss, Maria Drayss, Kristina Mott, Margret Droste, Bastian Just, David Stegner

Thromb Res· December 2022

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Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins.
Zahra Maqsood, Joanne C Clark, Eleyna M Martin, Yam Fung Hilaire Cheung, Luis A Morán, David Stegner

PLoS Comput Biol· November 2022

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