Publications by authors named "David T Dexter"

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Stereological analysis of cholinergic neurons within bilateral pedunculopontine nuclei in health and when affected by Parkinson's disease.
Puneet Kumar Sharma, Steve Gentleman, David Trevor Dexter, Ilse Sanet Pienaar

Brain Pathol· September 2025

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Treatment Selection and Prioritization for the EJS ACT-PD MAMS Trial Platform.
Cristina Gonzalez-Robles, Dilan Athauda, Thomas R Barber, Roger A Barker, David T Dexter

Mov Disord· July 2025

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A framework to standardize gait study protocols in Parkinson's disease.
Martina Mancini, Jeffrey M Hausdorff, Elisa Pelosin, Paolo Bonato, Richard Camicioli, David T Dexter

J Parkinsons Dis· February 2025

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Accelerating Parkinson's Disease drug development with federated learning approaches.
Amit Khanna, Jamie Adams, Chrystalina Antoniades, Bastiaan R Bloem, Camille Carroll, David T Dexter

NPJ Parkinsons Dis· November 2024

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A Coalition to Advance Treatments for Parkinson's Disease, Dementia with Lewy Bodies, and Related Disorders.
Catherine M Kopil, Angelica Asis, Clyde Campbell, Sohini Chowdhury, David T Dexter

J Parkinsons Dis· September 2024

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Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative.
Richard K Wyse, Tom Isaacs, Roger A Barker, Mark R Cookson, Ted M Dawson, David T Dexter

J Parkinsons Dis· June 2024

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Neuroprotective role for RORA in Parkinson's disease revealed by analysis of post-mortem brain and a dopaminergic cell line.
Felwah S Al-Zaid, Michael J Hurley, David T Dexter, Glenda E Gillies

NPJ Parkinsons Dis· July 2023

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Trial of Deferiprone in Parkinson's Disease.
David Devos, Julien Labreuche, Olivier Rascol, Jean-Christophe Corvol, Alain Duhamel, David T Dexter

N Engl J Med· December 2022

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Iron, Neuroinflammation and Neurodegeneration.
Roberta J Ward, David T Dexter, Robert R Crichton

Int J Mol Sci· June 2022

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GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop.
Roger A Barker, Anders Björklund, Don M Gash, Alan Whone, Amber Van Laar, David T Dexter

J Parkinsons Dis· August 2021

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Correction: Data Sharing Goals for Nonprofit Funders of Clinical Trials.
Timothy Coetzee, Mad Price Ball, Marc Boutin, Abby Bronson, David T Dexter

J Particip Med· June 2021

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Data Sharing Goals for Nonprofit Funders of Clinical Trials.
Timothy Coetzee, Mad Price Ball, Marc Boutin, Abby Bronson, David T Dexter

J Particip Med· March 2021

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Is Chelation Therapy a Potential Treatment for Parkinson's Disease?
Roberta J Ward, David T Dexter, Antonio Martin-Bastida, Robert R Crichton

Int J Mol Sci· March 2021

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Iron and inflammation: in vivo and post-mortem studies in Parkinson's disease.
Antonio Martin-Bastida, Bension Shlomo Tilley, Sukhi Bansal, Steve M Gentleman, David T Dexter

J Neural Transm (Vienna)· January 2021

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Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science.
Diane Stephenson, Robert Alexander, Varun Aggarwal, Reham Badawy, Lisa Bain, David T Dexter

Digit Biomark· November 2020

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DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats.
Puneet K Sharma, Lisa Wells, Gaia Rizzo, Joanna L Elson, Jan Passchier, David T Dexter

Neurotherapeutics· July 2020

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The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease.
Diane Stephenson, Derek Hill, Jesse M Cedarbaum, Maria Tome, Spiros Vamvakas, David T Dexter

J Parkinsons Dis· June 2020

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Novel 1-hydroxypyridin-2-one metal chelators prevent and rescue ubiquitin proteasomal-related neuronal injury in an in vitro model of Parkinson's disease.
Frank W Lewis, Safiya Fairooz, Joanna L Elson, Véronique Hubscher-Bruder, Jeremy Brandel, David T Dexter

Arch Toxicol· March 2020

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Quantification of blood-brain barrier transport and neuronal toxicity of unlabelled multiwalled carbon nanotubes as a function of surface charge.
Daniel Gonzalez-Carter, Angela E Goode, Darya Kiryushko, Seigo Masuda, Sheng Hu, David T Dexter

Nanoscale· November 2019

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Label-Free Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Sulfur-Producing Enzymes inside Microglia Cells following Exposure to Silver Nanowires.
Bey Fen Leo, Sarah Fearn, Daniel Gonzalez-Cater, Ioannis Theodorou, Pakatip Ruenraroengsak, David T Dexter

Anal Chem· September 2019

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The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival.
Stanislava Pankratova, Jorg Klingelhofer, Oksana Dmytriyeva, Sylwia Owczarek, Alexander Renziehausen, David T Dexter

Theranostics· August 2019

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Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease.
Klaus Romero, Daniela Conrado, Jackson Burton, Timothy Nicholas, Vikram Sinha, David T Dexter

Clin Transl Sci· May 2019

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L-DOPA functionalized, multi-branched gold nanoparticles as brain-targeted nano-vehicles.
Daniel A Gonzalez-Carter, Zhan Yuin Ong, Catriona M McGilvery, Iain E Dunlop, David T Dexter

Nanomedicine· January 2019

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The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease.
Ian F Harrison, Nicholas M Powell, David T Dexter

J Neurochem· January 2019

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The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease.
Diane Stephenson, Derek Hill, Jesse M Cedarbaum, Maria Tome, Spiros Vamvakas, David T Dexter

J Parkinsons Dis· January 2019

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