Publications by authors named "David T Shima"

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Reduced Glomerular Filtration in Diabetes Is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations.
Natalie C Finch, Sarah S Fawaz, Chris R Neal, Matthew J Butler, Vivian K Lee, David T Shima

J Am Soc Nephrol· June 2022

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Macrophages fine-tune pupil shape during development.
Moe Takahashi, Mika Misaki, Shinsuke Shibata, Takahito Iga, Tomoko Shindo, David T Shima

Dev Biol· August 2020

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A Na,K-ATPase-Fodrin-Actin Membrane Cytoskeleton Complex is Required for Endothelial Fenestra Biogenesis.
Meihua Ju, Sofia Ioannidou, Peter Munro, Olli Rämö, Helena Vihinen, David T Shima

Cells· June 2020

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Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis.
Jee Myung Yang, Chan Soon Park, Soo Hyun Kim, Tae Wook Noh, Ju-Hee Kim, David T Shima

Circ Res· March 2020

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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.
Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Gemmy Cheung Chui Ming, David T Shima

EMBO Mol Med· May 2019

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BTBR ob/ob mouse model of type 2 diabetes exhibits early loss of retinal function and retinal inflammation followed by late vascular changes.
Vivian K Lee, Brett M Hosking, Joanna Holeniewska, Ewa C Kubala, Peter Lundh von Leithner, David T Shima

Diabetologia· November 2018

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Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality.
Il-Kug Kim, Kangsan Kim, Eunhyeong Lee, Dong Sun Oh, Chan Soon Park, David T Shima

J Exp Med· March 2018

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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.
Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Chui Ming Gemmy Cheung, David T Shima

EMBO Mol Med· July 2017

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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.
Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Chui Ming Gemmy Cheung, David T Shima

EMBO Mol Med· November 2016

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Novel CCR3 Antagonists Are Effective Mono- and Combination Inhibitors of Choroidal Neovascular Growth and Vascular Permeability.
Nori Nagai, Meihua Ju, Kanako Izumi-Nagai, Scott J Robbie, James W Bainbridge, David T Shima

Am J Pathol· September 2015

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Differential apicobasal VEGF signaling at vascular blood-neural barriers.
Natalie Hudson, Michael B Powner, Mosharraf H Sarker, Thomas Burgoyne, Matthew Campbell, David T Shima

Dev Cell· September 2014

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Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.
Norihiro Nagai, Pete Lundh von Leithner, Kanako Izumi-Nagai, Brett Hosking, Bo Chang, David T Shima

Invest Ophthalmol Vis Sci· May 2014

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A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.
Owen A Anderson, Arthur Finkelstein, David T Shima

PLoS One· January 2014

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VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma.
Richard H Foxton, Arthur Finkelstein, Sauparnika Vijay, Annegret Dahlmann-Noor, Peng T Khaw, David T Shima

Am J Pathol· April 2013

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Assessing a novel depot delivery strategy for noninvasive administration of VEGF/PDGF RTK inhibitors for ocular neovascular disease.
Scott J Robbie, Peter Lundh von Leithner, Meihua Ju, Clemens A Lange, Andrew G King, David T Shima

Invest Ophthalmol Vis Sci· February 2013

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Do anti-angiogenic VEGF (VEGFxxxb) isoforms exist? A cautionary tale.
Sheila Harris, Madeleine Craze, Jillian Newton, Matthew Fisher, David T Shima

PLoS One· September 2012

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Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.
Huijun Luo, Kangxin Jin, Zhenhui Xie, Feng Qiu, Shengguo Li, David T Shima

Proc Natl Acad Sci U S A· February 2012

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Delivery of anti-angiogenic molecular therapies for retinal disease.
Owen A Anderson, James W B Bainbridge, David T Shima

Drug Discov Today· April 2010

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The heparin-binding domain confers diverse functions of VEGF-A in development and disease: a structure-function study.
Dominik Krilleke, Yin-Shan Eric Ng, David T Shima

Biochem Soc Trans· December 2009

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Delta-like 4 is indispensable in thymic environment specific for T cell development.
Katsuto Hozumi, Carolina Mailhos, Naoko Negishi, Ken-ichi Hirano, Takashi Yahata, David T Shima

J Exp Med· October 2008

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RGS5 expression is a quantitative measure of pericyte coverage of blood vessels.
Tracy S Mitchell, John Bradley, Gregory S Robinson, David T Shima, Yin-Shan Ng

Angiogenesis· September 2008

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Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors.
Gillian M Tozer, Simon Akerman, Neil A Cross, Paul R Barber, Meit A Björndahl, David T Shima

Cancer Res· April 2008

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Simultaneous but not prior inhibition of VEGF165 enhances the efficacy of photodynamic therapy in multiple models of ocular neovascularization.
Meihua Ju, Carolina Mailhos, John Bradley, Tracy Dowie, Mary Ganley, David T Shima

Invest Ophthalmol Vis Sci· February 2008

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Molecular mapping and functional characterization of the VEGF164 heparin-binding domain.
Dominik Krilleke, Andrea DeErkenez, William Schubert, Indrajit Giri, Gregory S Robinson, David T Shima

J Biol Chem· September 2007

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Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.
Kazuaki Nishijima, Yin-Shan Ng, Lichun Zhong, John Bradley, William Schubert, David T Shima

Am J Pathol· July 2007

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