Publications by authors named "David Taft"

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Impact of Second Opinions on Time to Treatment of Breast Cancer.
Pooja M Varman, Andrew Conner, William C Bennett, David Taft, Anna M Chichura

Ann Surg Oncol· October 2025

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PBPK Modeling of Acetaminophen in Pediatric Populations: Incorporation of SULT Enzyme Ontogeny to Predict Age-Dependent Metabolism and Systemic Exposure.
Sonia Sharma, David R Taft

Life (Basel)· July 2025

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Correction to "Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing".
Chaeho Moon, Sawittree Sahakijpijarn, Esther Y Maier, David R Taft, Miguel O Jara

Mol Pharm· June 2024

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Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing.
Chaeho Moon, Sawittree Sahakijpijarn, Esther Y Maier, David R Taft, Miguel O Jara

Mol Pharm· February 2024

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PBPK Modeling of Azithromycin Systemic Exposure in a Roux-en-Y Gastric Bypass Surgery Patient Population.
Suvarchala Kiranmai Avvari, Jaclyn A Cusumano, Vamshi Krishna Jogiraju, Pooja Manchandani, David R Taft

Pharmaceutics· October 2023

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Developing a Formulation Strategy Coupled with PBPK Modeling and Simulation for the Weakly Basic Drug Albendazole.
Harsh Shah, Kushal Shah, Bhavin Gajera, Rutesh H Dave, David R Taft

Pharmaceutics· March 2023

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Application of Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling in Preterm Neonates to Guide Gentamicin Dosing Decisions and Predict Antibacterial Effect.
Harshith Neeli, Nazeeh Hanna, Khaled Abduljalil, Jaclyn Cusumano, David R Taft

J Clin Pharmacol· October 2021

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Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example with Lamivudine.
Kushal Shah, Briann Fischetti, Agnes Cha, David R Taft

Curr Drug Discov Technol· September 2021

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Brentuximab vedotin in combination with nivolumab in relapsed or refractory Hodgkin lymphoma: 3-year study results.
Ranjana H Advani, Alison J Moskowitz, Nancy L Bartlett, Julie M Vose, Radhakrishnan Ramchandren, David Taft

Blood· August 2021

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Physiologically based pharmacokinetic modeling of altered tizanidine systemic exposure by CYP1A2 modulation: Impact of drug-drug interactions and cigarette consumption.
Vamshi Krishna Jogiraju, Tycho Heimbach, Yuliana Toderika, David R Taft

Drug Metab Pharmacokinet· April 2021

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Erratum to: Rapid, modular, and cost-effective generation of donor DNA constructs for CRISPR-based gene knock-in.
Yi-Jiun Chen, Ya-Yun Cheng, Weikang Wang, Xiao-Jun Tian, Daniel E Lefever, David A Taft

Biol Methods Protoc· November 2020

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Rapid, modular, and cost-effective generation of donor DNA constructs for CRISPR-based gene knock-in.
Yi-Jiun Chen, Ya-Yun Cheng, Weikang Wang, Xiao-Jun Tian, Daniel E Lefever, David A Taft

Biol Methods Protoc· March 2020

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Effect of Gender on the Pharmacokinetics of ON 123300, A Dual Inhibitor of ARK5 and CDK4/6 for the Treatment of Cancer, in Rats.
Jennypher Mudunuru, Chen Ren, David R Taft, Manoj Maniar

Eur J Drug Metab Pharmacokinet· August 2019

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Learn to segment single cells with deep distance estimator and deep cell detector.
Weikang Wang, David A Taft, Yi-Jiun Chen, Jingyu Zhang, Callen T Wallace

Comput Biol Med· May 2019

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Spatial clustering and common regulatory elements correlate with coordinated gene expression.
Jingyu Zhang, Hengyu Chen, Ruoyan Li, David A Taft, Guang Yao

PLoS Comput Biol· March 2019

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Real-World Experience With Higher-Than-Recommended Doses of Lamivudine in Patients With Varying Degrees of Renal Impairment.
Briann Fischetti, Kushal Shah, David R Taft, Leonard Berkowitz, Anjali Bakshi

Open Forum Infect Dis· October 2018

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Interim results of brentuximab vedotin in combination with nivolumab in patients with relapsed or refractory Hodgkin lymphoma.
Alex F Herrera, Alison J Moskowitz, Nancy L Bartlett, Julie M Vose, Radhakrishnan Ramchandren, David Taft

Blood· March 2018

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Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations.
Vamshi Krishna Jogiraju, Suvarchala Avvari, Rakesh Gollen, David R Taft

Biopharm Drug Dispos· October 2017

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Evaluating the Potential for Delivery of Irinotecan via the Buccal Route: Physicochemical Characterization and In Vitro Permeation Assessment Across Porcine Buccal Mucosa.
Vidhi Shah, Robert A Bellantone, David R Taft

AAPS PharmSciTech· April 2017

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Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromes.
Rami S Komrokji, Azra Raza, Jeffrey E Lancet, Chen Ren, David Taft

Br J Haematol· August 2013

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Determination of intestinal permeability of rigosertib (ON 01910.Na, Estybon): correlation with systemic exposure.
Michael P White, Mariana Babayeva, David R Taft, Manoj Maniar

J Pharm Pharmacol· July 2013

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Phase 1 study of intravenous rigosertib (ON 01910.Na), a novel benzyl styryl sulfone structure producing G2/M arrest and apoptosis, in adult patients with advanced cancer.
Takao Ohnuma, Deborah Lehrer, Chen Ren, Sool Yeon Cho, Manoj Maniar, David R Taft

Am J Cancer Res· July 2013

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Disposition of ON 01210.Na (Ex-RAD(R)), a novel radioprotectant, in the isolated perfused rat liver: probing metabolic inhibition to increase systemic exposure.
Mitalee Tamhane, Manoj Maniar, Chen Ren, Kenza E Benzeroual, David R Taft

J Pharm Sci· February 2013

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Radioprotective effects of ON 01210.Na upon oral administration.
Shubhankar Suman, Kamal Datta, Kathryn Doiron, Chen Ren, Ramesh Kumar, David R Taft

J Radiat Res· January 2013

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Aristolochic acid I metabolism in the isolated perfused rat kidney.
Horacio A Priestap, M Cecilia Torres, Robert A Rieger, Kathleen G Dickman, Tomoko Freshwater, David R Taft

Chem Res Toxicol· January 2012

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