Publications by authors named "David Takeda"

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Localized high-risk prostate cancer harbors an androgen receptor activity-low subpopulation susceptible to HER2 inhibition.
Scott Wilkinson, Anson T Ku, Rosina T Lis, Isaiah M King, Daniel Low, David Y Takeda

J Clin Invest· November 2025

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Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry.
Shan Li, Kaniz Fatema, Nidharshan Sundarraj, Arashdeep Singh, Padma Sheila Rajagopal, David Y Takeda

Nat Commun· November 2025

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Small cell carcinoma of the bladder: Review of pathogenesis, presentation, and management.
Nicholas I Simon, Andre R Kydd, Dilara Akbulut, David Takeda, Jaydira Del Rivero

Bladder Cancer· September 2025

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Plasma Cell-Free DNA Chromatin Immunoprecipitation Profiling Depicts Phenotypic and Clinical Heterogeneity in Advanced Prostate Cancer.
Joonatan Sipola, Aslı D Munzur, Edmond M Kwan, Clara C Y Seo, Benjamin J Hauk, David Y Takeda

Cancer Res· February 2025

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CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer.
Rachel R Xiang, Shin-Ai Lee, Caroline F Tyndall, Anusha R Bhatia, JuanJuan Yin, David Y Takeda

Cell Rep· February 2025

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Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry.
Sridhar Hannenhalli, Shan Li, Kaniz Fatema, Sundarraj Nidharshan, Arashdeep Singh, David Takeda

Res Sq· December 2024

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Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry.
Shan Li, Kaniz Fatema, Sundarraj Nidharshan, Arashdeep Singh, Padma Sheila Rajagopal, David Takeda

medRxiv· November 2024

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Unpacking circulating tumor DNA lends insight into prostate cancer biology and the clonal dynamics of metastasis.
David Y Takeda, Adam G Sowalsky

Cancer Cell· October 2022

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Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.
Sylvan C Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo, Tunc Morova, David Y Takeda

Nat Genet· September 2022

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Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.
Elizabeth H Stover, Coyin Oh, Paula Keskula, Atish D Choudhury, Yuen-Yi Tseng, David Y Takeda

Prostate· April 2022

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A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer.
Stephen Tang, Vidyalakshmi Sethunath, Nebiyou Y Metaferia, Marina F Nogueira, Daniel S Gallant, David Y Takeda

Cell Rep· February 2022

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Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer.
Sylvan C Baca, David Y Takeda, Ji-Heui Seo, Justin Hwang, Sheng Yu Ku

Nat Commun· March 2021

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Prostate cancer reactivates developmental epigenomic programs during metastatic progression.
Mark M Pomerantz, Xintao Qiu, Yanyun Zhu, David Y Takeda, Wenting Pan

Nat Genet· August 2020

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Mutational processes shape the landscape of TP53 mutations in human cancer.
Andrew O Giacomelli, Xiaoping Yang, Robert E Lintner, James M McFarland, Marc Duby, David Y Takeda

Nat Genet· October 2018

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Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.
Joaquim Bellmunt, Aly-Khan A Lalani, Sussana Jacobus, Stephanie A Wankowicz, Laura Polacek, David Y Takeda

Br J Cancer· September 2018

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Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Gabriel J Sandoval, John L Pulice, Hubert Pakula, Monica Schenone, David Y Takeda

Mol Cell· August 2018

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A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer.
David Y Takeda, Sándor Spisák, Ji-Heui Seo, Connor Bell, Edward O'Connor

Cell· July 2018

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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Aravind Subramanian, Rajiv Narayan, Steven M Corsello, David D Peck, Ted E Natoli, David Y Takeda

Cell· November 2017

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Association of tumour microRNA profiling with outcomes in patients with advanced urothelial carcinoma receiving first-line platinum-based chemotherapy.
Joaquim Bellmunt, Chensheng Willa Zhou, Stephanie A Mullane, Lillian Werner, Mary-Ellen Taplin, David Y Takeda

Br J Cancer· June 2016

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A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.
Gyorgy Petrovics, Hua Li, Tanja Stümpel, Shyh-Han Tan, Denise Young, David Takeda

EBioMedicine· December 2015

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The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.
Mark M Pomerantz, Fugen Li, David Y Takeda, Romina Lenci, Apurva Chonkar

Nat Genet· November 2015

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Beyond immune checkpoint blockade: new approaches to targeting host-tumor interactions in prostate cancer: report from the 2014 Coffey-Holden prostate cancer academy meeting.
Andrea K Miyahira, Haydn T Kissick, Jennifer L Bishop, David Y Takeda, Christopher E Barbieri

Prostate· March 2015

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Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.
Chiara Grisanzio, Lillian Werner, David Takeda, Bisola C Awoyemi, Mark M Pomerantz

Proc Natl Acad Sci U S A· July 2012

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Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells.
David Y Takeda, Yoshiyuki Shibata, Jeffrey D Parvin, Anindya Dutta

Genes Dev· December 2005

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Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase.
David Y Takeda, Jeffrey D Parvin, Anindya Dutta

J Biol Chem· June 2005

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