Publications by authors named "David Ugwu"

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Design, Synthesis, In Vivo Antimalarial Activity, and In Silico Studies of Sulfonamide-Alkanamido Thiazole-5-Carboxylate Derivatives.
James A Ezugwu, David I Ugwu, Mithun Rudrapal, Gourav Rakshit, Rahul Ghosh

Chem Biodivers· August 2025

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Anticancer properties of complexes derived from bidentate ligands.
David Izuchukwu Ugwu, Jeanet Conradie

J Inorg Biochem· September 2023

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Synthesis, Structure, Hirshfeld Surface Analysis, Non-Covalent Interaction, and In Silico Studies of 4-Hydroxy-1-[(4-Nitrophenyl)Sulfonyl]Pyrrolidine-2-Carboxyllic Acid.
David Izuchukwu Ugwu, Florence Uchenna Eze, Chigozie Julius Ezeorah, Lydia Rhyman, Ponnadurai Ramasami

J Chem Crystallogr· March 2023

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Structure and Computational Studies of New Sulfonamide Compound: {(4-nitrophenyl)sulfonyl}tryptophan.
Florence Uchenna Eze, Chigozie Julius Ezeorah, Blessing Chinweotito Ogboo, Obinna Chibueze Okpareke, Lydia Rhyman, Mirabel Chinasa Ugwu, David Izuchukwu Ugwu

Molecules· October 2022

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Carbohydrazide Analogues: A Review of Synthesis and Biological Activities.
Ebuka Leonard Onyeyilim, Mercy Amarachi Ezeokonkwo, David Izuchukwu Ugwu, Chiamaka Peace Uzoewulu, Florence Uchenna Eze, James Anayochukwu Ezugwu

Mini Rev Med Chem· April 2022

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Novel Dipeptides Bearing Sulfonamide as Antimalarial and Antitrypanosomal Agents: Synthesis and Molecular Docking.
Ogechi Chinelo Ekoh, Uchechukwu Okoro, David Ugwu, Rafat Ali, Sunday Okafor, Daniel Ugwuja

Med Chem· March 2022

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New chalcone derivatives as potential antimicrobial and antioxidant agent.
Emelda N Okolo, David I Ugwu, Benjamin E Ezema, Joseph C Ndefo, Florence U Eze, James A Ezugwu

Sci Rep· November 2021

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Synthesis and Biological Properties of some New Lead Sulphonamide and Carboxamide Scaffolds Bearing Coumarin Moieties.
Cosmas Chinweike Eze, Mercy Amarachukwu Ezeokonkwo, Benjamin Ebere Ezema, Abraham Efeturi Onoabedje, David Izuchukwu Ugwu

Mini Rev Med Chem· August 2021

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Novel Leu-Val Based Dipeptide as Antimicrobial and Antimalarial Agents: Synthesis and Molecular Docking.
James A Ezugwu, Uchechukwu C Okoro, Mercy A Ezeokonkwo, China R Bhimapaka, Sunday N Okafor, David I Ugwu

Front Chem· November 2020

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Synthesis and biological evaluation of Val-Val dipeptide-sulfonamide conjugates.
James A Ezugwu, Uchechukwu C Okoro, Mercy A Ezeokonkwo, Chinaraju Bhimapaka, Sunday N Okafor, David I Ugwu, Daniel I Ugwuja

Arch Pharm (Weinheim)· July 2020

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New carboxamides bearing benzenesulphonamides: Synthesis, molecular docking and pharmacological properties.
Florence Uchenna Eze, Uchechukwu Chris Okoro, David Izuchukwu Ugwu, Sunday N Okafor

Bioorg Chem· November 2019

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Biological Activity Evaluation of Some New Benzenesulphonamide Derivatives.
Florence Uchenna Eze, Uchechukwu Christopher Okoro, David Izuchukwu Ugwu, Sunday N Okafor

Front Chem· September 2019

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Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies.
David Izuchukwu Ugwu, Uchechukwu Christopher Okoro, Pius Onyeoziri Ukoha, Astha Gupta, Sunday N Okafor

J Enzyme Inhib Med Chem· December 2018

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Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent.
David I Ugwu, Uchechukwu C Okoro, Narendra K Mishra

Eur J Med Chem· June 2018

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Novel Phenoxazinones as potent agonist of PPAR-α: design, synthesis, molecular docking and in vivo studies.
David I Ugwu, Uchechukwu C Okoro, Narendra K Mishra, Sunday N Okafor

Lipids Health Dis· May 2018

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Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety.
David Izuchukwu Ugwu, Uchechukwu Chris Okoro, Narendra Kumar Mishra

PLoS One· February 2018

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New carboxamide derivatives bearing benzenesulphonamide as a selective COX-II inhibitor: Design, synthesis and structure-activity relationship.
David Izuchukwu Ugwu, Uchechukwu Chris Okoro, Hilal Ahmad

PLoS One· October 2017

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