Publications by authors named "David Vetrie"

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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, David Vetrie

Nat Commun· February 2024

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Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease.
Mary T Scott, Wei Liu, Rebecca Mitchell, Cassie J Clarke, Ross Kinstrie, David Vetrie

Nat Commun· January 2024

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Tyrosine Kinase Inhibitor Independent Gene Expression Signature in CML Offers New Targets for LSPC Eradication Therapy.
Eduardo Gómez-Castañeda, Lisa E M Hopcroft, Simon Rogers, Chinmay Munje, Joana Bittencourt-Silvestre, David Vetrie

Cancers (Basel)· October 2022

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The Spliceosome: A New Therapeutic Target in Chronic Myeloid Leukaemia.
Benjamin Lebecque, Celine Bourgne, Chinmay Munje, Juliette Berger, Thomas Tassin, David Vetrie

Cancers (Basel)· September 2022

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ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Angela Ianniciello, Martha M Zarou, Kevin M Rattigan, Mary Scott, Amy Dawson, David Vetrie

Sci Transl Med· September 2021

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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival.
Matthew E Massett, Laura Monaghan, Shaun Patterson, Niamh Mannion, Roderick P Bunschoten, David Vetrie

Cell Death Dis· June 2021

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The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML.
David Vetrie, G Vignir Helgason, Mhairi Copland

Nat Rev Cancer· March 2020

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Epigenetic Reprogramming and Emerging Epigenetic Therapies in CML.
Jane Bugler, Ross Kinstrie, Mary T Scott, David Vetrie

Front Cell Dev Biol· July 2019

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Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options.
Steffen Koschmieder, David Vetrie

Semin Cancer Biol· August 2018

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The chronic myeloid leukemia stem cell: stemming the tide of persistence.
Tessa L Holyoake, David Vetrie

Blood· March 2017

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CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.
Anuradha Tarafdar, Lisa E M Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, David Vetrie

Blood· January 2017

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Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition.
Mary T Scott, Koorosh Korfi, Peter Saffrey, Lisa E M Hopcroft, Ross Kinstrie, David Vetrie

Cancer Discov· November 2016

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Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells.
Sheela A Abraham, Lisa E M Hopcroft, Emma Carrick, Mark E Drotar, Karen Dunn, David Vetrie

Nature· June 2016

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Cancer: Repositioned to kill stem cells.
Tessa Holyoake, David Vetrie

Nature· September 2015

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Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL.
Yan Zhou, Sreenivasulu Kurukuti, Peter Saffrey, Milica Vukovic, Alison M Michie, David Vetrie

Blood· December 2013

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The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993.
David Vetrie, Igor Vořechovský, Paschalis Sideras, Jill Holland, Angela Davies

J Immunol· April 2012

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Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.
Pawandeep Dhami, Peter Saffrey, Alexander W Bruce, Shane C Dillon, Kelly Chiang, David Vetrie

PLoS One· August 2010

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Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus.
Pawandeep Dhami, Alexander W Bruce, Johanna H Jim, Shane C Dillon, Amanda Hall, David Vetrie

PLoS One· February 2010

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Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level.
Alexander W Bruce, Andrés J López-Contreras, Paul Flicek, Thomas A Down, Pawandeep Dhami, David Vetrie

Genome Res· June 2009

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Autosomal-dominant microtia linked to five tandem copies of a copy-number-variable region at chromosome 4p16.
Irina Balikova, Kevin Martens, Cindy Melotte, Mustapha Amyere, Steven Van Vooren, David Vetrie

Am J Hum Genet· January 2008

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The landscape of histone modifications across 1% of the human genome in five human cell lines.
Christoph M Koch, Robert M Andrews, Paul Flicek, Shane C Dillon, Ulaş Karaöz, David Vetrie

Genome Res· June 2007

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Nature· June 2007

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Requirement of bic/microRNA-155 for normal immune function.
Antony Rodriguez, Elena Vigorito, Simon Clare, Madhuri V Warren, Philippe Couttet, David Vetrie

Science· April 2007

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Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites.
George A Follows, Pawan Dhami, Berthold Göttgens, Alexander W Bruce, Peter J Campbell, David Vetrie

Genome Res· October 2006

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Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.
Patrick G Buckley, Kiran K Mantripragada, Teresita Díaz de Ståhl, Arkadiusz Piotrowski, Caisa M Hansson, David Vetrie

Hum Mutat· December 2005

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