Publications by authors named "David W C MacMillan"

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Deoxytrifluoromethylation of Alcohols.
Nicholas E Intermaggio, Agustin Millet, Dali L Davis, David W C MacMillan

July 2022

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Mutant p53 binds RNA to drive mitochondrial dysfunction.
Wuyue Zhou, Alice Long, Cameron J Douglas, Dalila Gallegos, James M Burke, David W C MacMillan

bioRxiv· November 2025

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The molecular mechanism of uptake and cell-to-cell transmission of arginine-containing dipeptide repeat proteins.
Alexandra B Sutter, Benito F Buksh, Jelena Mojsilovic-Petrovic, Casey Dalton, Nicholas A Till, David W C MacMillan

bioRxiv· November 2025

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A General Metallaphotoredox Platform for -Alkylated Sulfoximines as Bioisosteric Building Blocks.
Johannes J Großkopf, Danielle C Morgan, Aimee K Clarke, David W C MacMillan

J Am Chem Soc· October 2025

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Deoxygenative C()-N() Cross-Coupling Enabled by Nickel Metallaphotoredox Catalysis.
Ruizhe Chen, Taehyun Kim, Noah B Bissonnette, Robert T Martin, Joseph R Martinelli, David W C MacMillan

J Am Chem Soc· October 2025

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Antibody-bottlebrush prodrug conjugates for targeted cancer therapy.
Bin Liu, Hung V-T Nguyen, Yivan Jiang, Aiden X Wang, Valerie Lensch, David W C MacMillan

Nat Biotechnol· September 2025

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μMap-FFPE: A High-Resolution Protein Proximity Labeling Platform for Formalin-Fixed Paraffin-Embedded Tissue Samples.
Noah B Bissonnette, Marie E Zamanis, Steve D Knutson, Zane Boyer, Angelo Harris, David W C MacMillan

J Am Chem Soc· July 2025

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Radical Sorting Catalysis via Bimolecular Homolytic Substitution (S2): Opportunities for C(sp)-C(sp) Cross-Coupling Reactions.
Iona M McWhinnie, Robert T Martin, Jiaxin Xie, Ruizhe Chen, Cesar N Prieto Kullmer, David W C MacMillan

J Am Chem Soc· July 2025

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Micromapping (μMap) of HER2 Across Human Breast Cancers: Photocatalytic Proximity Labeling Identifies Primary Resistance Mechanisms and Functional Interactors.
Steve D Knutson, Jacob A Boyer, Danielle C Morgan, Johannes Großkopf, Joshua D Rabinowitz, David W C MacMillan

bioRxiv· June 2025

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Generalizing arene C-H alkylations by radical-radical cross-coupling.
Johannes Großkopf, Chawanansaya Gopatta, Robert T Martin, Alexander Haseloer, David W C MacMillan

Nature· May 2025

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Aryl Acid-Alcohol Cross-Coupling: C(sp)-C(sp) Bond Formation from Nontraditional Precursors.
Eva Lin, Johnny Z Wang, Edna Mao, Stephanie Tsang, Kurtis M Carsch, David W C MacMillan

J Am Chem Soc· May 2025

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Rapid Access to 3-Substituted Bicyclo[1.1.1]pentanes.
Katherine I Burton, David W C MacMillan

Chem· May 2025

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µMap proximity labeling in living cells reveals stress granule disassembly mechanisms.
Chenmengxiao Roderick Pan, Steve D Knutson, Sean W Huth, David W C MacMillan

Nat Chem Biol· April 2025

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Correction to "Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling".
Qinyan Cai, Iona M McWhinnie, Nathan W Dow, Amy Y Chan, David W C MacMillan

J Am Chem Soc· April 2025

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Correction to "Nontraditional Fragment Couplings of Alcohols and Carboxylic Acids: C(sp)-C(sp) Cross-Coupling via Radical Sorting".
Holt A Sakai, David W C MacMillan

J Am Chem Soc· April 2025

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Mesoscale proximity labeling to study macro changes to chromatin occupancy.
Cameron J Douglas, Preston Samowitz, Feifei Tong, Alice Long, Caitlin M Bradley, David W C MacMillan

bioRxiv· March 2025

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Parallel Proteomic and Transcriptomic Microenvironment Mapping (μMap) of Nuclear Condensates in Living Cells.
Steve D Knutson, Chenmengxiao Roderick Pan, Niels Bisballe, Brandon J Bloomer, Philip Raftopolous, David W C MacMillan

J Am Chem Soc· January 2025

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Aminoalkylation of Alkenes Enabled by Triple Radical Sorting.
William L Lyon, Johnny Z Wang, Jesús Alcázar, David W C MacMillan

J Am Chem Soc· January 2025

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Temporal Microenvironment Mapping (μMap) of Intracellular Trafficking Pathways of Cell-Penetrating Peptides Across the Blood-Brain Barrier.
Danielle C Morgan, Steve D Knutson, Chenmengxiao Roderick Pan, David W C MacMillan

bioRxiv· January 2025

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Iron-Catalyzed Cross-Electrophile Coupling for the Formation of All-Carbon Quaternary Centers.
Andria L Pace, Felix Xu, Wei Liu, Marissa N Lavagnino, David W C MacMillan

J Am Chem Soc· December 2024

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μMap-Interface: Temporal Photoproximity Labeling Identifies F11R as a Functional Member of the Transient Phagocytic Surfaceome.
Sean W Huth, Jacob B Geri, James V Oakley, David W C MacMillan

J Am Chem Soc· November 2024

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Unlocking carbene reactivity by metallaphotoredox α-elimination.
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan

Nature· July 2024

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Current advances in photocatalytic proximity labeling.
Steve D Knutson, Benito F Buksh, Sean W Huth, Danielle C Morgan, David W C MacMillan

Cell Chem Biol· June 2024

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Free-Radical Deoxygenative Amination of Alcohols via Copper Metallaphotoredox Catalysis.
William P Carson, Artem V Tsymbal, Robert W Pipal, Grant A Edwards, Joseph R Martinelli, David W C MacMillan

J Am Chem Soc· June 2024

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Triple Radical Sorting: Aryl-Alkylation of Alkenes.
Johnny Z Wang, Edna Mao, Jennifer A Nguyen, William L Lyon, David W C MacMillan

J Am Chem Soc· June 2024

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Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling.
Qinyan Cai, Iona M McWhinnie, Nathan W Dow, Amy Y Chan, David W C MacMillan

J Am Chem Soc· May 2024

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