Publications by authors named "David W Stepp"

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CD4 T Cells Expressing Viral Proteins Induce HIV-Associated Endothelial Dysfunction and Hypertension Through Interleukin 1α-Mediated Increases in Endothelial NADPH Oxidase 1.
Taylor C Kress, Candee T Barris, Laszlo Kovacs, Beryl N Khakina, Coleton R Jordan, David W Stepp

Circulation· April 2025

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PFKFB3 Connects Glycolytic Metabolism with Endothelial Dysfunction in Human and Rodent Obesity.
Robert K Batori, Zsuzsanna Bordan, Caleb A Padgett, Yuqing Huo, Feng Chen, David W Stepp

Antioxidants (Basel)· January 2025

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PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension.
Zsuzsanna Bordan, Robert K Batori, Stephen Haigh, Xueyi Li, Mary Louise Meadows, David W Stepp

Circulation· July 2024

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NADPH oxidase 1 promotes hepatic steatosis in obese mice and is abrogated by augmented skeletal muscle mass.
Sebastian Larion, Caleb A Padgett, James D Mintz, Jennifer A Thompson, Joshua T Butcher, David W Stepp

Am J Physiol Gastrointest Liver Physiol· March 2024

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Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1.
Caleb A Padgett, Róbert K Bátori, Andrew C Speese, Cody L Rosewater, Weston B Bush, David W Stepp

Arterioscler Thromb Vasc Biol· October 2023

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Early Endothelial Dysfunction in a Novel Model of Sustained Hyperphagia and Obesity in Mice Using a Brain Targeting Adeno-Associated Virus.
Hunter G Sellers, Caleb A Padgett, James D Mintz, Andrew C Speese, Zachary L Brown, David W Stepp

Arterioscler Thromb Vasc Biol· August 2023

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A Reappraisal of the Utility of L-012 to Measure Superoxide from Biologically Relevant Sources.
Stephen Haigh, Zach L Brown, Mitch A Shivers, Hunter G Sellers, Madison A West, David W Stepp

Antioxidants (Basel)· August 2023

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The Long Noncoding RNA Cardiac Mesoderm Enhancer-Associated Noncoding RNA (Carmn) Is a Critical Regulator of Gastrointestinal Smooth Muscle Contractile Function and Motility.
Xiangqin He, Kunzhe Dong, Jian Shen, Guoqing Hu, James D Mintz, David W Stepp

Gastroenterology· July 2023

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Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1.
Caleb A Padgett, Róbert K Bátori, Andrew C Speese, Cody L Rosewater, Weston B Bush, David W Stepp

bioRxiv· April 2023

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The biological clock enhancer nobiletin ameliorates steatosis in genetically obese mice by restoring aberrant hepatic circadian rhythm.
Sebastian Larion, Caleb A Padgett, Joshua T Butcher, James D Mintz, David J Fulton, David W Stepp

Am J Physiol Gastrointest Liver Physiol· October 2022

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Protective role of Cav-1 in pneumolysin-induced endothelial barrier dysfunction.
Robert K Batori, Feng Chen, Zsuzsanna Bordan, Stephen Haigh, Yunchao Su, David W Stepp

Front Immunol· August 2022

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Endothelin-1 response to whole-body vibration in obese and normal weight individuals.
Adeola A Sanni-Ajibaye, Anson M Blanks, Cassandra C Derella, Abigayle B Simon, Paula Rodriguez-Miguelez, David W Stepp

Physiol Rep· May 2022

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Obesity Induces Disruption of Microvascular Endothelial Circadian Rhythm.
Caleb A Padgett, Joshua T Butcher, Steven B Haigh, Andrew C Speese, Zachary L Corley, David W Stepp

Front Physiol· May 2022

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Protein kinase N2 connects blood flow with NO production in a double AKT.
David Jr Fulton, David W Stepp

J Clin Invest· November 2021

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Nf1 heterozygous mice recapitulate the anthropometric and metabolic features of human neurofibromatosis type 1.
Rebekah Tritz, Tyler Benson, Valerie Harris, Farlyn Z Hudson, James Mintz, David W Stepp

Transl Res· February 2021

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Origins of Hypertension in Obesity: Plain Vanilla(oid) or Multiple Flavors?
David J R Fulton, David W Stepp

Circulation· April 2020

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Whole body vibration elicits differential immune and metabolic responses in obese and normal weight individuals.
Anson M Blanks, Paula Rodriguez-Miguelez, Jacob Looney, Matthew A Tucker, Jinhee Jeong, David W Stepp

Brain Behav Immun Health· January 2020

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Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis.
Scott A Barman, Xueyi Li, Stephen Haigh, Dmitry Kondrikov, Keyvan Mahboubi, David W Stepp

Am J Physiol Lung Cell Mol Physiol· May 2019

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A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome.
Tyler W Benson, Neal L Weintraub, Ha Won Kim, Nichole Seigler, Sanjiv Kumar, David W Stepp

Lab Invest· October 2018

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Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding.
Tyler W Benson, Daniel S Weintraub, Matthew Crowe, Nicole K H Yiew, Orishebawo Popoola, David W Stepp

Mol Cell Endocrinol· September 2018

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Increased Muscle Mass Protects Against Hypertension and Renal Injury in Obesity.
Joshua T Butcher, James D Mintz, Sebastian Larion, Shuiqing Qiu, Ling Ruan, David W Stepp

J Am Heart Assoc· August 2018

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Galectin-3 Promotes Vascular Remodeling and Contributes to Pulmonary Hypertension.
Scott A Barman, Feng Chen, Xueyi Li, Stephen Haigh, David W Stepp

Am J Respir Crit Care Med· June 2018

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Hsp70 Suppresses Mitochondrial Reactive Oxygen Species and Preserves Pulmonary Microvascular Barrier Integrity Following Exposure to Bacterial Toxins.
Xueyi Li, Yanfang Yu, Boris Gorshkov, Stephen Haigh, Zsuzsanna Bordan, David W Stepp

Front Immunol· June 2018

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Effect of myostatin deletion on cardiac and microvascular function.
Joshua T Butcher, M Irfan Ali, Merry W Ma, Cameron G McCarthy, Bianca N Islam, David W Stepp

Physiol Rep· December 2017

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Genetic Deletion of NADPH Oxidase 1 Rescues Microvascular Function in Mice With Metabolic Disease.
Jennifer A Thompson, Sebastian Larion, James D Mintz, Eric J Belin de Chantemèle, David J Fulton, David W Stepp

Circ Res· August 2017

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