Publications by authors named "David Wai Chan"

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Oncogenic Activity and Sorafenib Sensitivity of p.S214C Mutation in Lung Cancer.
Carol Lee, Weixue Mu, Xi July Chen, Mandy Sze Man Chan, Zhishan Chen, Helen Hoi Yin Chan, David Wai Chan

Cancers (Basel)· July 2025

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Exosomes: Key Factors in Ovarian Cancer Peritoneal Metastasis and Drug Resistance.
Ming Shao, Yunran Gao, Xiling Xu, David Wai Chan, Juan Du

Biomolecules· September 2024

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An increase of serum CA-125 to two times of nadir level strongly predicts the image-identified relapse of serous ovarian cancer.
Kaiwen Du, Qian Li, Jin Huang, David Wai Chan, Jinjin Li, Xiaoxia Chang

Sci Rep· July 2024

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A Combination of Glutaminase Inhibitor 968 and PD-L1 Blockade Boosts the Immune Response against Ovarian Cancer.
Jing-Jing Wang, Michelle Kwan-Yee Siu, Yu-Xin Jiang, Thomas Ho-Yin Leung, David Wai Chan, Karen Kar-Loen Chan

Biomolecules· November 2021

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Infiltration of T cells promotes the metastasis of ovarian cancer cells via the modulation of metastasis-related genes and PD-L1 expression.
Jing-Jing Wang, Michelle Kwan-Yee Siu, Yu-Xin Jiang, David Wai Chan, Annie Nga-Yin Cheung, Karen Kar-Loen Chan

Cancer Immunol Immunother· November 2020

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Ascites-derived ALDH+CD44+ tumour cell subsets endow stemness, metastasis and metabolic switch via PDK4-mediated STAT3/AKT/NF-κB/IL-8 signalling in ovarian cancer.
Yu-Xin Jiang, Michelle Kwan-Yee Siu, Jing-Jing Wang, Xue-Tang Mo, Thomas Ho-Yin Leung, David Wai Chan, Karen Kar-Loen Chan

Br J Cancer· July 2020

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CD71 Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells.
Thomas Ho-Yin Leung, Hermit Wai-Man Tang, Michelle Kwan-Yee Siu, David Wai Chan, Karen Kar-Loen Chan

Mol Cancer Res· September 2019

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Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants.
Jack Ho Wong, Stephen Cho Wing Sze, Tzi Bun Ng, Randy Chi Fai Cheung, Chit Tam, Yau Sang Chan, David Wai Chan, Helen Chan

Curr Med Chem· March 2019

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GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade.
Mingo Ming-Ho Yung, Hermit Wai-Man Tang, Patty Chun-Hui Cai, Thomas Ho-Yin Leung, Siew-Fei Ngu, Karen Kar-Loen Chan, David Wai Chan

Theranostics· January 2019

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Methylation-associated silencing of promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways.
Kangmei Chen, Michelle Xin Liu, Celia Sze-Ling Mak, Mingo Ming-Ho Yung, Thomas Ho-Yin Leung, Karen Kar-Loen Chan, David Wai Chan

Theranostics· December 2018

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Human papillomavirus E6 protein enriches the CD55(+) population in cervical cancer cells, promoting radioresistance and cancer aggressiveness.
Thomas Ho-Yin Leung, Hermit Wai-Man Tang, Michelle Kwan-Yee Siu, David Wai Chan, Karen Kar-Loen Chan

J Pathol· February 2018

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ERBB2 mutation: A promising target in non-squamous cervical cancer.
Libing Xiang, Wei Jiang, Shuang Ye, Tiancong He, Xuan Pei, David Wai Chan

Gynecol Oncol· February 2018

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Targeting estrogen receptor subtypes (ERα and ERβ) with selective ER modulators in ovarian cancer.
Karen Kar-Loen Chan, Thomas Ho-Yin Leung, David Wai Chan, Na Wei, Grace Tak-Yi Lau

J Endocrinol· May 2014

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Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade.
Mingo Ming Ho Yung, David Wai Chan, Vincent Wing Sun Liu, Kwok-Ming Yao, Hextan Yuen-Sheung Ngan

BMC Cancer· July 2013

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LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.
Cuilan Li, Vincent Wing Sun Liu, David Wai Chan, Kwok Ming Yao, Hextan Yuen Sheung Ngan

Int J Gynecol Cancer· January 2012

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Inhibition of cervical cancer cell growth through activation of upstream kinases of AMP-activated protein kinase.
Sandy Yee Man Yu, David Wai Chan, Vincent Wing Sun Liu, Hextan Yuen Sheung Ngan

Tumour Biol· June 2009

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Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas.
Ka Yu Tse, Vincent Wing Sun Liu, David Wai Chan, Pui Man Chiu, Kar Fai Tam, Karen Kar Loen Chan

Tumour Biol· June 2009

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Identification of carboxypeptidase of glutamate like-B as a candidate suppressor in cell growth and metastasis in human hepatocellular carcinoma.
Pingping Zhang, David Wai Chan, Yiyi Zhu, Jin Jun Li, Irene Oi-Lin Ng

Clin Cancer Res· November 2006

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Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells.
David Wai Chan, Irene Oi-lin Ng

J Pathol· February 2006

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