Publications by authors named "David Warhurst"

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Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity.
Caio H Franco, David C Warhurst, Tapan Bhattacharyya, Ho Y A Au, Hai Le

Int J Parasitol Drugs Drug Resist· August 2020

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Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area.
Yan He, Susana Campino, Ernest Diez Benavente, David C Warhurst, Khalid B Beshir

PLoS One· December 2019

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Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance.
David C Warhurst, John C Craig, K Saki Raheem

PLoS One· July 2017

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Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V.
Mary C Oguike, Catherine O Falade, Elvis Shu, Izehiuwa G Enato, Ismaila Watila, David Warhurst

Int J Parasitol Drugs Drug Resist· December 2016

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Correction: Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance.
David C Warhurst, John C Craig, K Saki Raheem

PLoS One· August 2016

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The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine.
Gisela Henriques, Donelly A van Schalkwyk, Rebekah Burrow, David C Warhurst, Eloise Thompson

Antimicrob Agents Chemother· May 2015

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In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.
Subhashree Rout, David Charles Warhurst, Mrutyunjay Suar, Rajani Kanta Mahapatra

J Microbiol Methods· February 2015

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Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients.
Nahla B Gadalla, Maja Malmberg, Ishag Adam, Mary C Oguike, Khalid Beshir, David C Warhurst

J Antimicrob Chemother· January 2015

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Cryptosporidium prevalence and risk factors among mothers and infants 0 to 6 months in rural and semi-rural Northwest Tanzania: a prospective cohort study.
Sarah H Pedersen, Amanda L Wilkinson, Aura Andreasen, David C Warhurst, Safari M Kinung'hi

PLoS Negl Trop Dis· October 2014

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Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests.
Sören L Becker, Jürg Vogt, Stefanie Knopp, Marcus Panning, David C Warhurst

BMC Infect Dis· January 2013

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Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.
Carol E Griffin, Jonathan M Hoke, Upeka Samarakoon, Junhui Duan, Jianbing Mu, David C Warhurst

Antimicrob Agents Chemother· October 2012

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Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine.
Nahla B Gadalla, Ishag Adam, Salah-Eldin Elzaki, Sahar Bashir, Izdihar Mukhtar, David Warhurst

Antimicrob Agents Chemother· November 2011

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Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate.
J Brian de Souza, Uduak Okomo, Neal D Alexander, Naveed Aziz, Benjamin M J Owens, David C Warhurst

PLoS One· April 2010

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Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum.
Nahla B Gadalla, Salah Eldin Elzaki, Ebtihal Mukhtar, David C Warhurst, Badria El-Sayed

Malar J· March 2010

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Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola.
Michela Menegon, Richard J Pearce, Walter O Inojosa, Vincenzo Pisani, Paulo M Abel, David C Warhurst

Trop Med Int Health· October 2009

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Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity.
Ruqaiyyah Siddiqui, Abdul Matin, David Warhurst, Monique Stins, Naveed Ahmed Khan

Antimicrob Agents Chemother· December 2007

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Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.
Quinton L Fivelman, Ipemida S Adagu, David C Warhurst

Antimicrob Agents Chemother· June 2007

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Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases.
David C Warhurst, John C Craig, Ipemida S Adagu, R Kiplin Guy, Peter B Madrid

Biochem Pharmacol· June 2007

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PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.
Patrick G Bray, Mathirut Mungthin, Ian M Hastings, Giancarlo A Biagini, Dauda K Saidu, David C Warhurst

Mol Microbiol· October 2006

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Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania.
Michael Alifrangis, Michael B Dalgaard, John P Lusingu, Lasse S Vestergaard, Trine Staalsoe, David C Warhurst

J Infect Dis· June 2006

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Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo.
Andrew V Stachulski, Neil G Berry, A C Lilian Low, Shelley L Moores, Eleanor Row, David C Warhurst

J Med Chem· February 2006

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Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates.
Amir Hossein Maghsood, James Sissons, Mostafa Rezaian, Debbie Nolder, David Warhurst

J Med Microbiol· August 2005

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Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum.
Quinton L Fivelman, Ipemida S Adagu, David C Warhurst

Antimicrob Agents Chemother· November 2004

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Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells.
Samantha Jayasekera, James Sissons, Julie Tucker, Claire Rogers, Debbie Nolder, David Warhurst

J Med Microbiol· October 2004

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Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone.
Caroline Lang'at-Thoruwa, Geoffrey C Kirby, J David Phillipson, David C Warhurst, Robert A Watt

J Nat Prod· November 2003

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