Publications by authors named "David Y Hui"

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The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis.
Hima Bindu Durumutla, April Haller, Greta Noble, Ashok Daniel Prabakaran, Kevin McFarland, David Y Hui

J Clin Invest· September 2025

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Distinct Roles of apoE Receptor-2 Cytoplasmic Domain Splice Variants in Cardiometabolic Disease Modulation.
Anja Jaeschke, April Haller, David Y Hui

Biomedicines· July 2025

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The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis.
Hima Bindu Durumutla, April Haller, Greta Noble, Ashok Daniel Prabakaran, Kevin McFarland, David Y Hui

bioRxiv· April 2025

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ApoE Receptor-2 R952Q Variant in Macrophages Elevates Soluble LRP1 to Potentiate Hyperlipidemia and Accelerate Atherosclerosis in Mice.
Vanessa Turkson, April Haller, Anja Jaeschke, David Y Hui

Arterioscler Thromb Vasc Biol· January 2025

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Inactivation of Group 1B Phospholipase A Enhances Disease Recovery and Reduces Experimental Colitis in Mice.
April M Haller, Patrick R Wolfkiel, Anja Jaeschke, David Y Hui

Int J Mol Sci· November 2023

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Different sensitivity to diet-induced hyperinsulinemia and hyperglycemia between mice with global or bone marrow-specific apoE receptor-2 deficiency.
Patrick R Wolfkiel, April M Haller, Jillian Kirby, Anja Jaeschke, David Y Hui

Am J Physiol Regul Integr Comp Physiol· July 2023

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Sexual Dimorphism in Lipid Metabolism and Gut Microbiota in Mice Fed a High-Fat Diet.
Qi Zhu, Nathan Qi, Ling Shen, Chunmin C Lo, Meifeng Xu, David Y Hui

Nutrients· May 2023

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Perivascular adipose tissue promotes vascular dysfunction in murine lupus.
Hong Shi, Brandee Goo, David Kim, Taylor C Kress, Mourad Ogbi, David Y Hui

Front Immunol· April 2023

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Receptor-independent fluid-phase macropinocytosis promotes arterial foam cell formation and atherosclerosis.
Hui-Ping Lin, Bhupesh Singla, WonMo Ahn, Pushpankur Ghoshal, Maria Blahove, David Y Hui

Sci Transl Med· September 2022

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Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases.
Jeyashree Alagarsamy, Anja Jaeschke, David Y Hui

Int J Mol Sci· August 2022

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Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats.
Jose A Godoy-Lugo, Max A Thorwald, David Y Hui, Akira Nishiyama, Daisuke Nakano

Endocrine· January 2022

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LDL receptor-related protein 1 and its interacting partners in tissue homeostasis.
Anja Jaeschke, David Y Hui

Curr Opin Lipidol· October 2021

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Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
Haiyan Chu, Anastasia Sacharidou, An Nguyen, Chun Li, Ken L Chambliss, David Y Hui

Circ Res· September 2021

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Distinct pro-inflammatory properties of myeloid cell-derived apolipoprotein E2 and E4 in atherosclerosis promotion.
Emily Igel, April Haller, Patrick R Wolfkiel, Melissa Orr-Asman, Anja Jaeschke, David Y Hui

J Biol Chem· September 2021

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Hepatic LDL receptor-related protein-1 deficiency alters mitochondrial dynamics through phosphatidylinositol 4,5-bisphosphate reduction.
Sivaprakasam Chinnarasu, Fawzi Alogaili, Kevin E Bove, Anja Jaeschke, David Y Hui

J Biol Chem· August 2021

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Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis.
Laurent Calvier, Navid Manouchehri, Anastasia Sacharidou, Chieko Mineo, Philip W Shaul, David Y Hui

Sci Immunol· August 2021

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Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis.
Moises A Huaman, Joseph E Qualls, Shinsmon Jose, Stephanie M Schmidt, Anissa Moussa, David Y Hui

Front Immunol· June 2021

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Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation.
Anja Jaeschke, April Haller, James G Cash, Christopher Nam, Emily Igel, David Y Hui

J Lipid Res· December 2020

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Mice lacking global Stap1 expression do not manifest hypercholesterolemia.
Babunageswararao Kanuri, Vincent Fong, April Haller, David Y Hui, Shailendra B Patel

BMC Med Genet· November 2020

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Distinct Influence of Hypercaloric Diets Predominant with Fat or Fat and Sucrose on Adipose Tissue and Liver Inflammation in Mice.
Caíque S M Fonseca, Joshua E Basford, David G Kuhel, Eddy S Konaniah, James G Cash, David Y Hui

Molecules· September 2020

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Hepatic HAX-1 inactivation prevents metabolic diseases by enhancing mitochondrial activity and bile salt export.
Fawzi Alogaili, Sivaprakasam Chinnarasu, Anja Jaeschke, Evangelia G Kranias, David Y Hui

J Biol Chem· April 2020

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Prefrontal Cortex Regulates Chronic Stress-Induced Cardiovascular Susceptibility.
Derek Schaeuble, Amy E B Packard, Jessica M McKlveen, Rachel Morano, Sarah Fourman, David Y Hui

J Am Heart Assoc· December 2019

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ApoER2 (Apolipoprotein E Receptor-2) Deficiency Accelerates Smooth Muscle Cell Senescence via Cytokinesis Impairment and Promotes Fibrotic Neointima After Vascular Injury.
Ravi K Komaravolu, Meaghan D Waltmann, Eddy Konaniah, Anja Jaeschke, David Y Hui

Arterioscler Thromb Vasc Biol· October 2019

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Enhancer of zeste homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: Role of apolipoprotein E.
Nicole K H Yiew, Charlotte Greenway, Abdalrahman Zarzour, Samah Ahmadieh, Brandee Goo, David Y Hui

J Biol Chem· May 2019

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Therapeutic reduction of lysophospholipids in the digestive tract recapitulates the metabolic benefits of bariatric surgery and promotes diabetes remission.
James G Cash, Eddy Konaniah, Narasimha Hegde, David G Kuhel, Miki Watanabe, David Y Hui

Mol Metab· October 2018

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