Publications by authors named "Dean D Metcalfe"

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Evolution of mast cell research associated with the Laboratory of Allergic Diseases, 1985-2022: Summary of the 2023 NIAID Symposium.
Hirsh D Komarow, Gunnar Nilsson, Yoshimichi Okayama, Yoseph Mekori, Ana Olivera, Dean D Metcalfe

J Allergy Clin Immunol· September 2025

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Treatment of indolent systemic mastocytosis with sarilumab is not supported in a randomized trial.
Hirsh D Komarow, Jing Wang, Robin Eisch, Linda Scott, Erica H Brittain, Dean D Metcalfe

J Allergy Clin Immunol Glob· August 2025

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Prevalence of myeloid gene alterations in paediatric cutaneous and systemic mastocytosis.
Xiaoping Sun, Chen Wang, Dean D Metcalfe, Melody C Carter, Irina Maric

Br J Haematol· August 2025

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Fire ant-venom anaphylaxis prevalence in the general population and patients with systemic mastocytosis.
Jeremy C McMurray, Brandon J Schornack, Karla E Adams, Robert L McCoy, Amanda K Marshall, Dean D Metcalfe

Front Allergy· March 2025

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Harmonization of Diagnostic Criteria in Mastocytosis for Use in Clinical Practice: WHO vs ICC vs AIM/ECNM.
Peter Valent, Karin Hartmann, Gregor Hoermann, Andreas Reiter, Iván Alvarez-Twose, Dean D Metcalfe

J Allergy Clin Immunol Pract· December 2024

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Increased expression of formyl peptide receptor-1 by basophils from patients with mastocytosis.
Yuzhi Yin, Jenny Min Li, Dean D Metcalfe, Ana Olivera, Pamela A Frischmeyer-Guerrerio

J Allergy Clin Immunol Glob· November 2024

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Autoantibodies to type I interferons in patients with systemic mastocytosis.
Vivian Cao, Serena J Lee, Yun Bai, Steven M Holland, Lindsey B Rosen, Dean D Metcalfe

J Allergy Clin Immunol Glob· August 2024

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Mast cell activation syndrome: Current understanding and research needs.
Mariana Castells, Matthew P Giannetti, Matthew J Hamilton, Peter Novak, Olga Pozdnyakova, Dean D Metcalfe

J Allergy Clin Immunol· August 2024

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Sphingosine-1-Phosphate Receptor 4 links neutrophils and early local inflammation to lymphocyte recruitment into the draining lymph node to facilitate robust germinal center formation.
Andrea J Luker, Abigail Wukitch, Joseph M Kulinski, Sundar Ganesan, Juraj Kabat, Dean D Metcalfe

Front Immunol· August 2024

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Standardized indolent systemic mastocytosis evaluations across a health care system: implications for screening accuracy.
Jeremy C McMurray, Curtis S Pacheco, Brandon J Schornack, Xiaoping Sun, Janet A Brunader, Dean D Metcalfe

Blood· July 2024

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Prevalence and impact of the M541L variant in patients with mastocytosis.
Luisa N Dominguez Aldama, Eric Karlins, Xiaoping Sun, Daniel Veltri, Hirsh D Komarow, Dean D Metcalfe

Oncotarget· July 2024

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Activation of the receptor KIT induces the secretion of exosome-like small extracellular vesicles.
Annika Pfeiffer, Geethani Bandara, Jennifer D Petersen, Guido H Falduto, Joshua Zimmerberg, Dean D Metcalfe

J Extracell Biol· January 2024

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The Normal Range of Baseline Tryptase Should Be 1 to 15 ng/mL and Covers Healthy Individuals With HαT.
Peter Valent, Gregor Hoermann, Patrizia Bonadonna, Karin Hartmann, Wolfgang R Sperr, Dean D Metcalfe

J Allergy Clin Immunol Pract· October 2023

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Challenges in applying diagnostic criteria for systemic mastocytosis.
Nathan A Boggs, Xiaoping Sun, Jonathan J Lyons, Jeremy C McMurray, David M Rose, Dean D Metcalfe

Blood Adv· July 2023

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Research Advances in Mast Cell Biology and Their Translation Into Novel Therapies for Anaphylaxis.
Melanie C Dispenza, Dean D Metcalfe, Ana Olivera

J Allergy Clin Immunol Pract· July 2023

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sCD14 and Intestinal Fatty Acid Binding Protein Are Elevated in the Serum of Patients With Idiopathic Anaphylaxis.
Vivian T Cao, Melody C Carter, Jason M Brenchley, Hyejeong Bolan, Linda M Scott, Dean D Metcalfe

J Allergy Clin Immunol Pract· July 2023

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Targeted Therapy for the Predominant Form of Mastocytosis.
Dean D Metcalfe

NEJM Evid· June 2023

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Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.
Jack Chovanec, Ilker Tunc, Jason Hughes, Joseph Halstead, Allyson Mateja, Dean D Metcalfe

Blood Adv· May 2023

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CRISPR/Cas9-engineering of HMC-1.2 cells renders a human mast cell line with a single D816V-KIT mutation: An improved preclinical model for research on mastocytosis.
Geethani Bandara, Guido H Falduto, Andrea Luker, Yun Bai, Annika Pfeiffer, Dean D Metcalfe

Front Immunol· April 2023

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Reply to "MRGPRX2: A novel biomarker in mastocytosis?".
Hirsh D Komarow, Melody C Carter, Dean D Metcalfe, Hydar Ali

J Allergy Clin Immunol Pract· February 2023

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Assessment of low immunoglobulin levels and clinical manifestations in patients with mastocytosis.
Ayelet Makovoz, Kimberley L Cousins, Luisa N Dominguez Aldama, Hyejeong Bolan, Dean D Metcalfe

J Allergy Clin Immunol Glob· February 2023

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New Insights into the Pathogenesis of Mastocytosis: Emerging Concepts in Diagnosis and Therapy.
Peter Valent, Cem Akin, Wolfgang R Sperr, Hans-Peter Horny, Michel Arock, Dean D Metcalfe

Annu Rev Pathol· January 2023

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Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations.
Morgan N Similuk, Jia Yan, Rajarshi Ghosh, Andrew J Oler, Luis M Franco, Dean D Metcalfe

J Allergy Clin Immunol· October 2022

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Selective immunocapture reveals neoplastic human mast cells secrete distinct microvesicle- and exosome-like populations of KIT-containing extracellular vesicles.
Annika Pfeiffer, Jennifer D Petersen, Guido H Falduto, David Eric Anderson, Joshua Zimmerberg, Dean D Metcalfe

J Extracell Vesicles· September 2022

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Recent Developments in the Field of Mast Cell Disorders: Classification, Prognostication, and Management.
Peter Valent, Michel Arock, Cem Akin, Dean D Metcalfe

J Allergy Clin Immunol Pract· August 2022

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