Publications by authors named "Dean Felsher"

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EcDNA-borne structural variants drive oncogenic fusion transcript amplification.
Hyerim Yi, Shu Zhang, Jason Swinderman, Yanbo Wang, Vishnupriya Kanakaveti, Dean W Felsher

Cell· January 2026

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Targeting the MYC oncogene with a selective bi-steric mTORC1 inhibitor elicits tumor regression in MYC-driven cancers.
Wadie D Mahauad-Fernandez, Yu Chi Yang, Ian Lai, Jangho Park, Lilian Yao, Dean W Felsher

Cell Chem Biol· August 2025

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Sex disparity in survival outcomes of advanced gastric adenocarcinoma.
Minggui Pan, Meng M Tong, Jack Stover, Tina Huang, Arun Dang, Dean Felsher

BJC Rep· August 2025

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Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice.
Shelly Beer, David I Bellovin, Joyce S Lee, Kimberly Komatsubara, Lora S Wang, Dean W Felsher

Mol Ther· June 2025

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Association of HER2 amplification or overexpression with overall survival in advanced upper gastrointestinal adenocarcinomas.
Minggui Pan, Arun Dang, Tina Huang, Jack Stover, Meng M Tong, Dean Felsher

BJC Rep· May 2025

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Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma.
Jiayu Zhang, Jinneng Yang, Jinyan Luo, Weili Wu, Haidan Luo, Dean W Felsher

Nat Commun· April 2025

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EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAs.
Hyerim Yi, Shu Zhang, Jason Swinderman, Yanbo Wang, Vishnupriya Kanakaveti, Dean W Felsher

bioRxiv· April 2025

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Spatial analysis reveals targetable macrophage-mediated mechanisms of immune evasion in hepatocellular carcinoma minimal residual disease.
Lea Lemaitre, Nia Adeniji, Akanksha Suresh, Reshma Reguram, Josephine Zhang, Dean W Felsher

Nat Cancer· October 2024

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A big step for MYC-targeted therapies.
Danielle F Atibalentja, Anja Deutzmann, Dean W Felsher

Trends Cancer· May 2024

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Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma.
Anja Deutzmann, Delaney K Sullivan, Renumathy Dhanasekaran, Wei Li, Xinyu Chen, Dean W Felsher

Nat Commun· February 2024

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Single-nucleus chromatin accessibility identifies a critical role for TWIST1 in idiopathic pulmonary fibrosis myofibroblast activity.
Eleanor Valenzi, Harinath Bahudhanapati, Jiangning Tan, Tracy Tabib, Daniel I Sullivan, Dean W Felsher

Eur Respir J· July 2023

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MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint.
Benjamin A H Smith, Anja Deutzmann, Kristina M Correa, Corleone S Delaveris, Renumathy Dhanasekaran, Dean W Felsher

Proc Natl Acad Sci U S A· March 2023

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MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages.
Renumathy Dhanasekaran, Aida S Hansen, Jangho Park, Lea Lemaitre, Ian Lai, Dean W Felsher

Cancer Res· February 2023

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MYC oncogene elicits tumorigenesis associated with embryonic, ribosomal biogenesis, and tissue-lineage dedifferentiation gene expression changes.
Delaney K Sullivan, Anja Deutzmann, Josiah Yarbrough, Maya S Krishnan, Arvin M Gouw, Dean W Felsher

Oncogene· November 2022

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Tackling heterogeneity in treatment-resistant breast cancer using a broad-spectrum therapeutic approach.
Leroy Lowe, J William LaValley, Dean W Felsher

Cancer Drug Resist· October 2022

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Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.
Ling Tong, Minjie Shan, Wen Zou, XianLing Liu, Dean W Felsher

Front Oncol· August 2022

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Na/H-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells.
Yao-Yu Gong, Hongguang Shao, Yu Li, Patricia Brafford, Zachary E Stine, Dean W Felsher

Cancer Res Commun· August 2022

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Azapodophyllotoxin Causes Lymphoma and Kidney Cancer Regression by Disrupting Tubulin and Monoglycerols.
Arvin M Gouw, Vineet Kumar, Angel Resendez, Fidelia B Alvina, Natalie S Liu, Dean W Felsher

ACS Med Chem Lett· April 2022

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Anti-PD-L1 F(ab) Conjugated PEG-PLGA Nanoparticle Enhances Immune Checkpoint Therapy.
Christina K Lee, Danielle F Atibalentja, Lilian E Yao, Jangho Park, Sibu Kuruvilla, Dean W Felsher

Nanotheranostics· March 2022

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The MYC oncogene - the grand orchestrator of cancer growth and immune evasion.
Renumathy Dhanasekaran, Anja Deutzmann, Wadie D Mahauad-Fernandez, Aida S Hansen, Arvin M Gouw, Dean W Felsher

Nat Rev Clin Oncol· January 2022

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Generation of a Tetracycline Regulated Mouse Model of MYC-Induced T-Cell Acute Lymphoblastic Leukemia.
Wadie D Mahauad-Fernandez, Kavya Rakhra, Dean W Felsher

Methods Mol Biol· August 2021

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Genomic Analysis of Vascular Invasion in HCC Reveals Molecular Drivers and Predictive Biomarkers.
Maya S Krishnan, Anand Rajan Kd, Jangho Park, Vinodhini Arjunan, Fernando Jose Garcia Marques, Dean W Felsher

Hepatology· June 2021

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Twist1 is required for the development of UVB-induced squamous cell carcinoma.
Fernando Eguiarte-Solomon, Nicholas Blazanin, Okkyung Rho, Steve Carbajal, Dean W Felsher

Mol Carcinog· May 2021

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Smart Self-Assembly Amphiphilic Cyclopeptide-Dye for Near-Infrared Window-II Imaging.
Hao Chen, Kangquan Shou, Si Chen, Chunrong Qu, Zhiming Wang, Dean W Felsher

Adv Mater· April 2021

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A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation.
Sharon S Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Dean W Felsher

Sci Rep· January 2021

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