Publications by authors named "Dean G Tang"

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Elimination of docetaxel-induced senescence attenuates malignant progression in RB1-deficient CRPC.
Huilan Su, Liqun Huang, Wenwen Xia, Dean G Tang, Jianjun Zhou

Cell Oncol (Dordr)· December 2025

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Phase Ib study of enzalutamide with venetoclax in patients with metastatic castration-resistant prostate cancer.
Stuthi Perimbeti, Anmbreen Jamroze, Dharmesh Gopalakrishnan, Rohit Jain, Changchuan Jiang, Dean G Tang

Cancer Chemother Pharmacol· November 2025

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Advancing Cancer Biology: Highlights from the 2025 FASEB SRC on Cellular Plasticity in Cancer.
Hans Clevers, Ankur Sharma, Sendurai A Mani, Anna Golebiewska, Axel Behrens, Dean G Tang

Cancer Heterog Plast· October 2025

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Cell-resolved high-dimensional imaging analysis, therapeutic modeling, and a Phase Ib clinical study establish BCL-2 as a target across heterogeneous CRPC subtypes.
Anmbreen Jamroze, Xiaozhuo Liu, Surui Hou, Wen Jess Li, Han Yu, Dean G Tang

bioRxiv· July 2025

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Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival.
Xiaozhuo Liu, Eduardo Cortes, Yibing Ji, Kathy Zhao, Julian Ho, Dean G Tang

bioRxiv· June 2025

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Loss of expression in a subset of human prostate cancers promotes tumor growth through accumulation of p62.
Daric J Wible, Wen Jess Li, Xiaozhuo Liu, Manu M Sebastian, Dean G Tang

bioRxiv· May 2025

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Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
Dean G Tang

J Clin Invest· April 2025

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Phase Ib Study of Enzalutamide with Venetoclax in Patients with Metastatic Castration-Resistant Prostate Cancer.
Stuthi Perimbeti, Anmbreen Jamroze, Dharmesh Gopalakrishnan, Rohit Jain, Changchuan Jiang, Dean G Tang

medRxiv· April 2025

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Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition.
Antonino Glaviano, Hannah Si-Hui Lau, Lukas M Carter, E Hui Clarissa Lee, Hiu Yan Lam, Dean G Tang

J Hematol Oncol· January 2025

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Tissue factor pathway inhibitor-2 (TFPI-2)-an underappreciated partaker in cancer and metastasis.
Marek Z Wojtukiewicz, Marta Mysliwiec, Anna Tokajuk, Joanna Kruszewska, Barbara Politynska, Dean G Tang

Cancer Metastasis Rev· December 2024

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Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer.
Xiang Ling, Wenjie Wu, Li Yan, Leslie Curtin, Melanie M Farrauto, Dean G Tang

J Pharm Anal· November 2024

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Inhibition of PRMT5 moderately suppresses prostate cancer growth in vivo but enhances its response to immunotherapy.
Qinju He, Yuanzhen Zhang, Wenchao Li, Saisai Chen, Jiangling Xiong, Dean G Tang

Cancer Lett· October 2024

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Lipopolyplex-formulated mRNA cancer vaccine elicits strong neoantigen-specific T cell responses and antitumor activity.
Ting Fan, Congcong Xu, Jichuan Wu, Yihua Cai, Wanlu Cao, Yuying Tang, Dean G Tang

Sci Adv· October 2024

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Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.
Jason S Kirk, Jie Wang, Mark Long, Spencer Rosario, Amanda Tracz, Dean G Tang

Cell Stem Cell· August 2024

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Treatment-induced stemness and lineage plasticity in driving prostate cancer therapy resistance.
Anmbreen Jamroze, Xiaozhuo Liu, Dean G Tang

Cancer Heterog Plast· August 2024

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- A new journal dedicated to understanding cancer cell states and interactions with the tumor microenvironment.
Dean G Tang

Cancer Heterog Plast· July 2024

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The Complex Role of Thrombin in Cancer and Metastasis: Focus on Interactions with the Immune System.
Karolina Aleksandrowicz, Dominika Hempel, Barbara Polityńska, Anna M Wojtukiewicz, Kenneth V Honn, Dean G Tang

Semin Thromb Hemost· April 2024

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Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises.
Wen Jess Li, Yunfei Wang, Xiaozhuo Liu, Shan Wu, Moyi Wang, Dean G Tang

Int J Mol Sci· February 2024

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Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises.
Wen Jess Li, Yunfei Wang, Xiaozhuo Liu, Shan Wu, Moyi Wang, Dean G Tang

bioRxiv· January 2024

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STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Jan Pencik, Cecile Philippe, Michaela Schlederer, Emine Atas, Matteo Pecoraro, Simone Tangermann, Dean G Tang

Mol Cancer· August 2023

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Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence.
Fengzhi Li, Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Dean G Tang

J Exp Clin Cancer Res· August 2023

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Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.
Jason S Kirk, Jie Wang, Amanda Tracz, Mark Long, Spencer R Rosario, Dean G Tang

bioRxiv· March 2023

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Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness.
Xiaozhuo Liu, Wen Jess Li, Igor Puzanov, David W Goodrich, Gurkamal Chatta, Dean G Tang

Essays Biochem· September 2022

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MicroRNA-34a, Prostate Cancer Stem Cells, and Therapeutic Development.
Wen Jess Li, Xiaozhuo Liu, Emily M Dougherty, Dean G Tang

Cancers (Basel)· September 2022

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A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60.
Rahul Kumar, Ajay K Chaudhary, Jordan Woytash, Joseph R Inigo, Abhiram A Gokhale, Dean G Tang

J Clin Invest· July 2022

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