Publications by authors named "Dean Kavanagh"

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Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression.
Rachel J Stapley, Xenia Sawkulycz, Gabriel H M Araujo, Maximilian Englert, Lourdes Garcia-Quintanilla, Dean Kavanagh

J Clin Invest· October 2025

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Spleen Tyrosine Kinase Inhibition Mitigates Hemin-Induced Thromboinflammation in an Organ-Specific Manner in Sickle Cell Mice.
Juma El-Awaisi, Gina Perrella, Nicolas Mayor, Veronika Tinkova, Simon J Cleary, Dean Kavanagh

Arterioscler Thromb Vasc Biol· October 2025

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Impact of chronic hyperglycaemia on the coronary microcirculation - benefits of targeting IL-36 and diet reversal.
Juma El-Awaisi, Dean Kavanagh, Silke Heising, Ina Maria Schiessl, Simon J Cleary

Basic Res Cardiol· June 2025

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Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection.
Marisol Perez-Toledo, Nonantzin Beristain-Covarrubias, Jamie Pillaye, Ruby R Persaud, Edith Marcial-Juarez, Dean P Kavanagh

Nat Commun· March 2025

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A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit.
Jun Sun, Francisca Rojo-Cortes, Suzana Ulian-Benitez, Manuel G Forero, Guiyi Li, Dean Kavanagh

Elife· December 2024

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Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice.
Joshua H Bourne, Gina Perrella, Juma El-Awaisi, Lauren V Terry, Veronika Tinkova, Dean Kavanagh

J Thromb Haemost· July 2024

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Monitoring coronary blood flow by laser speckle contrast imaging after myocardial ischaemia reperfusion injury in adult and aged mice.
Juma El-Awaisi, Dean P J Kavanagh, Neena Kalia

Front Cardiovasc Med· February 2024

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Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy.
Fawaz O Alenazy, Maan H Harbi, Dean P Kavanagh, Joshua Price, Paul Brady

J Thromb Haemost· November 2023

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Improving vasculoprotective effects of MSCs in coronary microvessels - benefits of 3D culture, sub-populations and heparin.
Kobkaew Bumroongthai, Dean P J Kavanagh, Paul Genever, Neena Kalia

Front Immunol· November 2023

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Aging modulates homeostatic leukocyte trafficking to the peritoneal cavity in a sex-specific manner.
Sophie J Hopkin, Laleh Pezhman, Jenefa Begum, Dean Kavanagh, Helen M McGettrick

J Leukoc Biol· September 2023

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Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/reperfusion injury in mice.
Juma El-Awaisi, Dean Pj Kavanagh, Marco R Rink, Chris J Weston, Nigel E Drury

JCI Insight· March 2022

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Neutrophil extracellular traps and inflammasomes cooperatively promote venous thrombosis in mice.
Joana Campos, Tatyana Ponomaryov, Alexandra De Prendergast, Katharine Whitworth, Christopher W Smith, Dean Kavanagh

Blood Adv· May 2021

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Lymphatic blood filling in CLEC-2-deficient mouse models.
Elizabeth J Haining, Kate L Lowe, Surasak Wichaiyo, Raghu P Kataru, Zoltan Nagy, Dean Pj Kavanagh

Platelets· April 2021

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Live Intravital Imaging of Cellular Trafficking in the Cardiac Microvasculature-Beating the Odds.
Dean Philip John Kavanagh, Neena Kalia

Front Immunol· November 2020

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Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.
Myriam Chimen, Aigli Evryviadou, Clare L Box, Matthew J Harrison, Jon Hazeldine, Dean Kavanagh

Haematologica· May 2020

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Tify: A quality-based frame selection tool for improving the output of unstable biomedical imaging.
Dean Philip John Kavanagh, Meurig Thomas Gallagher, Neena Kalia

PLoS One· December 2019

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Imaging the injured beating heart intravitally and the vasculoprotection afforded by haematopoietic stem cells.
Dean P J Kavanagh, Adam B Lokman, Georgiana Neag, Abigail Colley, Neena Kalia

Cardiovasc Res· November 2019

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Characterising the mechanical properties of haematopoietic and mesenchymal stem cells using micromanipulation and atomic force microscopy.
Mingming Du, Dean Kavanagh, Neena Kalia, Zhibing Zhang

Med Eng Phys· November 2019

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Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties.
Mingming Du, Dean Kavanagh, Zhibing Zhang, Neena Kalia

Stem Cells Int· September 2019

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Modulating the Adhesion of Haematopoietic Stem Cells with Chemokines to Enhance Their Recruitment to the Ischaemically Injured Murine Kidney.
Rebecca L White, Gerard Nash, Dean P J Kavanagh, Caroline O S Savage, Neena Kalia

PLoS One· October 2017

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Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
Andrew King, Diarmaid D Houlihan, Dean Kavanagh, Debashis Haldar, Nguyet Luu

Gastroenterology· July 2017

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Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.
Dean P J Kavanagh, Shankar Suresh, Philip N Newsome, Jon Frampton, Neena Kalia

Stem Cells· September 2015

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Mesenchymal stem cell priming: fine-tuning adhesion and function.
Dean P J Kavanagh, Joseph Robinson, Neena Kalia

Stem Cell Rev Rep· August 2014

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Enhancing the adhesion of hematopoietic precursor cell integrins with hydrogen peroxide increases recruitment within murine gut.
Dean P J Kavanagh, Adrian I Yemm, J Steven Alexander, Jon Frampton, Neena Kalia

Cell Transplant· April 2014

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Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo.
Dean P J Kavanagh, Adrian I Yemm, Yan Zhao, Jon Frampton, Neena Kalia

PLoS One· September 2013

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