Publications by authors named "Dean R Appling"

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Metabotype analysis of Mthfd1l-null mouse embryos using desorption electrospray ionization mass spectrometry imaging.
Amanda Vaughn, Rachel J DeHoog, Livia S Eberlin, Dean R Appling

Anal Bioanal Chem· May 2021

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Deletion of neural tube defect-associated gene Mthfd1l causes reduced cranial mesenchyme density.
Minhye Shin, Amanda Vaughn, Jessica Momb, Dean R Appling

Birth Defects Res· November 2019

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Deletion of the neural tube defect-associated gene disrupts one-carbon and central energy metabolism in mouse embryos.
Joshua D Bryant, Shannon R Sweeney, Enrique Sentandreu, Minhye Shin, Hélène Ipas, Dean R Appling

J Biol Chem· April 2018

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Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase.
Minhye Shin, Jessica Momb, Dean R Appling

Cancer Metab· December 2017

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Lester Reed: A "complex" man who loved science.
Marvin L Hackert, Dean R Appling, Alan M Lambowitz

Proc Natl Acad Sci U S A· May 2015

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Mitochondrial one-carbon metabolism and neural tube defects.
Jessica Momb, Dean R Appling

Birth Defects Res A Clin Mol Teratol· August 2014

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Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.
Minhye Shin, Joshua D Bryant, Jessica Momb, Dean R Appling

J Biol Chem· May 2014

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Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.
Jessica Momb, Jordan P Lewandowski, Joshua D Bryant, Rebecca Fitch, Deborah R Surman, Dean R Appling

Proc Natl Acad Sci U S A· January 2013

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Mammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues.
Swetha Bolusani, Blake A Young, Nicola A Cole, Anne S Tibbetts, Jessica Momb, Dean R Appling

J Biol Chem· February 2011

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Frank Chytil (1924-2010).
Dean R Appling, David E Ong

J Nutr· October 2010

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Compartmentalization of Mammalian folate-mediated one-carbon metabolism.
Anne S Tibbetts, Dean R Appling

Annu Rev Nutr· August 2010

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Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.
Schuyler T Pike, Rashmi Rajendra, Karen Artzt, Dean R Appling

J Biol Chem· February 2010

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Yeast AEP3p is an accessory factor in initiation of mitochondrial translation.
Changkeun Lee, Anne S Tibbetts, Gisela Kramer, Dean R Appling

J Biol Chem· December 2009

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Human mitochondrial C1-tetrahydrofolate synthase: submitochondrial localization of the full-length enzyme and characterization of a short isoform.
Priya Prasannan, Dean R Appling

Arch Biochem Biophys· January 2009

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The gene for cobalamin-independent methionine synthase is essential in Candida albicans: a potential antifungal target.
Huda S Suliman, Dean R Appling, Jon D Robertus

Arch Biochem Biophys· November 2007

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Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.
Changkeun Lee, Gisela Kramer, David E Graham, Dean R Appling

J Biol Chem· September 2007

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Global metabolic changes following loss of a feedback loop reveal dynamic steady states of the yeast metabolome.
Peng Lu, Anupama Rangan, Sherwin Y Chan, Dean R Appling, David W Hoffman

Metab Eng· January 2007

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Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase.
Addie S Walkup, Dean R Appling

Arch Biochem Biophys· October 2005

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Kinetic and structural analysis of active site mutants of monofunctional NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Wendi Wagner, Andrew P Breksa, Arthur F Monzingo, Dean R Appling, Jon D Robertus

Biochemistry· October 2005

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Purification and properties of cobalamin-independent methionine synthase from Candida albicans and Saccharomyces cerevisiae.
Huda S Suliman, Gregory M Sawyer, Dean R Appling, Jon D Robertus

Arch Biochem Biophys· September 2005

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Characterization of the C2 subdomain of yeast mitochondrial initiation factor 2.
Cristiana Garofalo, Gisela Kramer, Dean R Appling

Arch Biochem Biophys· July 2005

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Characterization of the rat cytoplasmic C1-tetrahydrofolate synthase gene and analysis of its expression in liver regeneration and fetal development.
Katherine M Howard, Stephanie J Muga, Liwen Zhang, Anice E Thigpen, Dean R Appling

Gene· November 2003

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Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls.
Priya Prasannan, Schuyler Pike, Kun Peng, Barry Shane, Dean R Appling

J Biol Chem· October 2003

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Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.
Sherwin Y Chan, Dean R Appling

J Biol Chem· October 2003

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Mammalian mitochondrial initiation factor 2 supports yeast mitochondrial translation without formylated initiator tRNA.
Anne S Tibbetts, Lena Oesterlin, Sherwin Y Chan, Gisela Kramer, Boyd Hardesty, Dean R Appling

J Biol Chem· August 2003

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